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The map label for this gene is asnC

Identifier: 138895750

GI number: 138895750

Start: 2238821

End: 2240113

Strand: Reverse

Name: asnC

Synonym: GTNG_2106

Alternate gene names: 138895750

Gene position: 2240113-2238821 (Counterclockwise)

Preceding gene: 138895751

Following gene: 138895749

Centisome position: 63.1

GC content: 51.66

Gene sequence:

>1293_bases
GTGAAAACGACGATTGCTGAAGTGAACCAATATGTAGGTCAAGAAGTCACGATCGGCGCTTGGTTGGCGAACAAGCGCTC
GAGCGGAAAAATCGCCTTTTTACAGCTGCGTGATGGGACTGGCTTTATTCAAGGTGTAGTTGAAAAAGCGAACGTCTCAG
AAGAGGTATTTCAACGTGCGAAAACGCTGACGCAAGAAACGTCGCTCTATGTGACCGGCACGGTGCGCGTCGACGAGCGT
TCACCGTTCGGTTATGAGCTTTCGGTGACGAACATACAGGTCATCAATGAAGCGGTCGATTATCCGATTACGCCAAAAGA
ACACGGTGTCGAGTTTTTAATGGATCATCGTCACCTTTGGCTTCGTTCGCGGCGCCAACATGCGATCATGAAAATCCGCA
ACGAATTGATCCGTGCGACGTATGAGTTTTTTAACGAACGTGGCTTCGTCAAAGTCGATGCGCCGATTTTGACTGGCAGC
GCACCGGAAGGAACGACCGAGCTGTTCCATACGAAGTATTTTGACGAGGATGCCTATTTATCGCAAAGCGGCCAGCTATA
TATGGAAGCAGCAGCCATGGCGCTCGGTAAAGTGTTTTCGTTCGGTCCGACATTCCGTGCCGAAAAGTCGAAAACGCGCC
GCCATTTGATCGAATTTTGGATGATCGAGCCTGAAATGGCGTTTTACGAATTTGAAGACAATTTGCGGCTGCAAGAAGAG
TATGTCTCTTATCTCGTACAGTCGGTGCTTAGCCGTTGCCAACTTGAGCTCGGGCGCCTTGGACGCGACGTCACCAAGCT
TGAGCTTGTCAAGCCGCCGTTTCCGCGTCTAACGTATGACGAAGCGATCAAGCTGCTGCATGACAAAGGGTTTACCGATA
TCGAATGGGGCGATGACTTCGGTGCGCCGCATGAGACAGCCATCGCTGAAAGCTTCGACAAGCCGGTGTTTATCACTCAC
TACCCGACGTCGTTAAAGCCGTTTTATATGCAGCCAGATCCGAACCGTCCGGACGTCGTGCTATGTGCTGATTTAATCGC
GCCGGAGGGATACGGGGAGATTATCGGCGGTTCCGAGCGCATTCATGATTATGAGCTGCTCAAGCAGCGTCTCGAGGAGC
ATCATTTGCCGCTTGAAGCATATGAATGGTATTTAGATTTGCGCAAATACGGTTCCGTGCCGCACTCCGGATTCGGGCTC
GGCCTCGAGCGAACGGTTGCTTGGATTTGCGGCGTTGAGCATGTACGCGAGACGATCCCGTTTCCGCGGTTGCTCAACCG
TCTATACCCGTAA

Upstream 100 bases:

>100_bases
GGCCAGAGGCGAAAGGTTTCCTTGGCCGTTGCCGTCGTTTCGCCAGAACGATATAATAGCGAATGAGATGGACGTGTCGA
TTATTGGAGGGAATGTGTAC

Downstream 100 bases:

>100_bases
AAAAACCCCCTGCAAAAAGGGGGTTTTTTCGCTAGTGTCATGTTATACTATAGTTGAGGTGCATCGGCATGGAAAAGAAA
AAGGTGGCCGAATGGCTGGC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKTTIAEVNQYVGQEVTIGAWLANKRSSGKIAFLQLRDGTGFIQGVVEKANVSEEVFQRAKTLTQETSLYVTGTVRVDER
SPFGYELSVTNIQVINEAVDYPITPKEHGVEFLMDHRHLWLRSRRQHAIMKIRNELIRATYEFFNERGFVKVDAPILTGS
APEGTTELFHTKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFYEFEDNLRLQEE
YVSYLVQSVLSRCQLELGRLGRDVTKLELVKPPFPRLTYDEAIKLLHDKGFTDIEWGDDFGAPHETAIAESFDKPVFITH
YPTSLKPFYMQPDPNRPDVVLCADLIAPEGYGEIIGGSERIHDYELLKQRLEEHHLPLEAYEWYLDLRKYGSVPHSGFGL
GLERTVAWICGVEHVRETIPFPRLLNRLYP

Sequences:

>Translated_430_residues
MKTTIAEVNQYVGQEVTIGAWLANKRSSGKIAFLQLRDGTGFIQGVVEKANVSEEVFQRAKTLTQETSLYVTGTVRVDER
SPFGYELSVTNIQVINEAVDYPITPKEHGVEFLMDHRHLWLRSRRQHAIMKIRNELIRATYEFFNERGFVKVDAPILTGS
APEGTTELFHTKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFYEFEDNLRLQEE
YVSYLVQSVLSRCQLELGRLGRDVTKLELVKPPFPRLTYDEAIKLLHDKGFTDIEWGDDFGAPHETAIAESFDKPVFITH
YPTSLKPFYMQPDPNRPDVVLCADLIAPEGYGEIIGGSERIHDYELLKQRLEEHHLPLEAYEWYLDLRKYGSVPHSGFGL
GLERTVAWICGVEHVRETIPFPRLLNRLYP
>Mature_430_residues
MKTTIAEVNQYVGQEVTIGAWLANKRSSGKIAFLQLRDGTGFIQGVVEKANVSEEVFQRAKTLTQETSLYVTGTVRVDER
SPFGYELSVTNIQVINEAVDYPITPKEHGVEFLMDHRHLWLRSRRQHAIMKIRNELIRATYEFFNERGFVKVDAPILTGS
APEGTTELFHTKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFYEFEDNLRLQEE
YVSYLVQSVLSRCQLELGRLGRDVTKLELVKPPFPRLTYDEAIKLLHDKGFTDIEWGDDFGAPHETAIAESFDKPVFITH
YPTSLKPFYMQPDPNRPDVVLCADLIAPEGYGEIIGGSERIHDYELLKQRLEEHHLPLEAYEWYLDLRKYGSVPHSGFGL
GLERTVAWICGVEHVRETIPFPRLLNRLYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=438, Percent_Identity=35.8447488584475, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI4758762, Length=442, Percent_Identity=34.1628959276018, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI45439306, Length=454, Percent_Identity=30.8370044052863, Blast_Score=189, Evalue=4e-48,
Organism=Escherichia coli, GI1787161, Length=450, Percent_Identity=37.3333333333333, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1789256, Length=461, Percent_Identity=26.0303687635575, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790571, Length=459, Percent_Identity=25.7080610021786, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788173, Length=246, Percent_Identity=25.2032520325203, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71984122, Length=450, Percent_Identity=35.3333333333333, Blast_Score=251, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17551876, Length=466, Percent_Identity=28.5407725321888, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17556372, Length=412, Percent_Identity=31.3106796116505, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI32566633, Length=301, Percent_Identity=26.578073089701, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994340, Length=484, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17535927, Length=484, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17535925, Length=484, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321807, Length=444, Percent_Identity=35.5855855855856, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6319872, Length=467, Percent_Identity=30.406852248394, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6323011, Length=457, Percent_Identity=31.5098468271335, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6325153, Length=247, Percent_Identity=27.1255060728745, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921528, Length=431, Percent_Identity=34.338747099768, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI19922416, Length=452, Percent_Identity=31.6371681415929, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI17136276, Length=461, Percent_Identity=27.9826464208243, Blast_Score=178, Evalue=6e-45,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_GEOTN (A4IQ54)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126203.1
- ProteinModelPortal:   A4IQ54
- SMR:   A4IQ54
- STRING:   A4IQ54
- GeneID:   4967034
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_2106
- NMPDR:   fig|420246.5.peg.2013
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   A4IQ54
- ProtClustDB:   PRK03932
- BioCyc:   GTHE420246:GTNG_2106-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 49514; Mature: 49514

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTIAEVNQYVGQEVTIGAWLANKRSSGKIAFLQLRDGTGFIQGVVEKANVSEEVFQRA
CCCHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHH
KTLTQETSLYVTGTVRVDERSPFGYELSVTNIQVINEAVDYPITPKEHGVEFLMDHRHLW
HHHHHCCEEEEEEEEEECCCCCCCEEEEECHHHHHHHHHCCCCCCHHHCHHHHHHHHHHH
LRSRRQHAIMKIRNELIRATYEFFNERGFVKVDAPILTGSAPEGTTELFHTKYFDEDAYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCHHHHHHHHCCCCHHH
SQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFYEFEDNLRLQEE
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCEEEEECCCCCHHHH
YVSYLVQSVLSRCQLELGRLGRDVTKLELVKPPFPRLTYDEAIKLLHDKGFTDIEWGDDF
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
GAPHETAIAESFDKPVFITHYPTSLKPFYMQPDPNRPDVVLCADLIAPEGYGEIIGGSER
CCCCHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCHH
IHDYELLKQRLEEHHLPLEAYEWYLDLRKYGSVPHSGFGLGLERTVAWICGVEHVRETIP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
FPRLLNRLYP
HHHHHHHHCC
>Mature Secondary Structure
MKTTIAEVNQYVGQEVTIGAWLANKRSSGKIAFLQLRDGTGFIQGVVEKANVSEEVFQRA
CCCHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHH
KTLTQETSLYVTGTVRVDERSPFGYELSVTNIQVINEAVDYPITPKEHGVEFLMDHRHLW
HHHHHCCEEEEEEEEEECCCCCCCEEEEECHHHHHHHHHCCCCCCHHHCHHHHHHHHHHH
LRSRRQHAIMKIRNELIRATYEFFNERGFVKVDAPILTGSAPEGTTELFHTKYFDEDAYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCHHHHHHHHCCCCHHH
SQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFYEFEDNLRLQEE
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCEEEEECCCCCHHHH
YVSYLVQSVLSRCQLELGRLGRDVTKLELVKPPFPRLTYDEAIKLLHDKGFTDIEWGDDF
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
GAPHETAIAESFDKPVFITHYPTSLKPFYMQPDPNRPDVVLCADLIAPEGYGEIIGGSER
CCCCHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCHH
IHDYELLKQRLEEHHLPLEAYEWYLDLRKYGSVPHSGFGLGLERTVAWICGVEHVRETIP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
FPRLLNRLYP
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA