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The map label for this gene is bioF

Identifier: 138895669

GI number: 138895669

Start: 2144743

End: 2144979

Strand: Reverse

Name: bioF

Synonym: GTNG_2025

Alternate gene names: NA

Gene position: 2144979-2144743 (Counterclockwise)

Preceding gene: 138895671

Following gene: 138895668

Centisome position: 60.42

GC content: 50.21

Gene sequence:

>237_bases
TTGAACGACGAGCGGAACCATGCAAGCTTAATTGATGGGATTCACTTGAGCAAAGTCACCTGTTTCCGTTACCGTCGTAA
TGACGTCGATGATGAAAGCAATCTCTGCCAGGAAACCGAAAACGGATGGTCACCGCCACGGTCTTCAATATGGATGGAGC
GATTATCGGAGCTTGTCGAGTTGAAACGACGCTATCGCTTTCTGACACCGCCGTGGTGGACGACGATGTTGAGCTAG

Upstream 100 bases:

>100_bases
AGCTATGTTAAAACAGTGAAAAAAAGCAGAATCCGCACTCATTTTCAATAGCGGCTATGCTGCGAATATCGGTGTACTGG
TTCGCCGCGATGACCTCGTC

Downstream 100 bases:

>100_bases
CTGTTGGCTACATCGCTTTCGCAGGAAAGAAGATGGAGGTCATTTAGTAGGTGGAACAAAGGGGGAAAAACAAAAAACCA
ACCGGTTGTTTTTCCGGCTG

Product: Defective 8-amino-7-oxononanoate synthase

Products: NA

Alternate protein names: AONS/AKB ligase; 7-keto-8-amino-pelargonic acid synthase; 7-KAP synthase; KAPA synthase; 8-amino-7-ketopelargonate synthase; Alpha-oxoamine synthase; L-alanine--pimeloyl-CoA ligase [H]

Number of amino acids: Translated: 78; Mature: 78

Protein sequence:

>78_residues
MNDERNHASLIDGIHLSKVTCFRYRRNDVDDESNLCQETENGWSPPRSSIWMERLSELVELKRRYRFLTPPWWTTMLS

Sequences:

>Translated_78_residues
MNDERNHASLIDGIHLSKVTCFRYRRNDVDDESNLCQETENGWSPPRSSIWMERLSELVELKRRYRFLTPPWWTTMLS
>Mature_78_residues
MNDERNHASLIDGIHLSKVTCFRYRRNDVDDESNLCQETENGWSPPRSSIWMERLSELVELKRRYRFLTPPWWTTMLS

Specific function: Catalyzes the decarboxylative condensation of pimeloyl- CoA and L-alanine to produce 8-amino-7-oxononanoate (AON), coenzyme A and/or converts 2-amino-3-ketobutyrate to glycine and acetyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR004723
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.3.1.29; =2.3.1.47 [H]

Molecular weight: Translated: 9416; Mature: 9416

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDERNHASLIDGIHLSKVTCFRYRRNDVDDESNLCQETENGWSPPRSSIWMERLSELVE
CCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LKRRYRFLTPPWWTTMLS
HHHHHCCCCCCHHHHHCC
>Mature Secondary Structure
MNDERNHASLIDGIHLSKVTCFRYRRNDVDDESNLCQETENGWSPPRSSIWMERLSELVE
CCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LKRRYRFLTPPWWTTMLS
HHHHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA