Click here to switch to the map view.

The map label for this gene is glsA

Identifier: 138895668

GI number: 138895668

Start: 2143258

End: 2144187

Strand: Reverse

Name: glsA

Synonym: GTNG_2024

Alternate gene names: 138895668

Gene position: 2144187-2143258 (Counterclockwise)

Preceding gene: 138895669

Following gene: 138895667

Centisome position: 60.39

GC content: 52.04

Gene sequence:

>930_bases
ATGCCTGTGTACAACAAAGAAGAGCTTGTCCGCTTTGTCGAAGAAGCAAAACAGTACGCCCGTTACGGAAAAGTGGCTGA
TTACATTCCCGCCTTAGGTAAGGCGAATCCGAACGAGCTGTCGATTGCCGTGTACACCGCAGACGGAAAAGTCGTTGATG
CCGGCGATGTGACAGTCAAGGTGACGCTACAGAGCATTTCCAAAATTCTCGCACTGGCCCTTGTGCTGATCGACCGCGGC
GAAGACGAGGTGTTTCGCAAAGTTGGTATGGAGCCGACGGGCGATCCGTTTAACTCCATTGCTAAGCTCGAGGAAGTGCA
GCCGTCCAAACCACTCAACCCAATGATTAACGCCGGGGCGTTGGCGGTGACGCACATGATTCGCGGCCGTTCTGTCGAAG
AGCGGCTCGAGCGGCTTTTGGCATTCATCCGCCGATTGGCAGGCAACGAACAGATCACGTATTCGGAAGAAGTGGCTCAA
TCCGAGTTTGAAACCGCGTTTTTAAACCGGTCACTTTGCTATTTTTTGAAACAGCACGGCATTATCGATGAAGATGTTGA
AGAGTTGATGGACTTGTATACGAAGCAATGTGCCGTTGAGATGACGTGCATTGATTTGGCGCGCATCGGCTTAGTATTCG
CACTTGACGGGCGCGACCCGCATTCGGGTGAGCTGCTCATGCCTCTTGATGTGGCTCGTATTTGCAAAACGTTCATGGTC
ACGTGCGGCATGTACAACGCTTCAGGCGAGTTTGCCATTAAAATTGGCATTCCAGCCAAAAGCGGTGTTTCCGGCGGCAT
TCTTGCTGCCGTCCCAGGGCGATGCGGCATCGGTATTTTCGGTCCGGCGCTCGATGATAAAGGGAACAGCTTGACCGGGG
TGAAGCTGCTCGAGCGGCTATCCAAAACATATTCATTAAGCATTTTTTAA

Upstream 100 bases:

>100_bases
AACATTCCGTTTGGACAAGGCCGAGTGCGCCTGTCGATTCCTAGCTGTTTGCATTGTTCATGCATAAAACAGGAAAAATC
AGCCATACTAACCATCGGTG

Downstream 100 bases:

>100_bases
GGAGGAGACGAACATGAAAGCGTTTATGGTTCAGTTTCATCGCGAAGATCATGTGGAGGCGATGAACGTCGGCAAATTGA
ACCAAGACGAATTTGACAAG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPVYNKEELVRFVEEAKQYARYGKVADYIPALGKANPNELSIAVYTADGKVVDAGDVTVKVTLQSISKILALALVLIDRG
EDEVFRKVGMEPTGDPFNSIAKLEEVQPSKPLNPMINAGALAVTHMIRGRSVEERLERLLAFIRRLAGNEQITYSEEVAQ
SEFETAFLNRSLCYFLKQHGIIDEDVEELMDLYTKQCAVEMTCIDLARIGLVFALDGRDPHSGELLMPLDVARICKTFMV
TCGMYNASGEFAIKIGIPAKSGVSGGILAAVPGRCGIGIFGPALDDKGNSLTGVKLLERLSKTYSLSIF

Sequences:

>Translated_309_residues
MPVYNKEELVRFVEEAKQYARYGKVADYIPALGKANPNELSIAVYTADGKVVDAGDVTVKVTLQSISKILALALVLIDRG
EDEVFRKVGMEPTGDPFNSIAKLEEVQPSKPLNPMINAGALAVTHMIRGRSVEERLERLLAFIRRLAGNEQITYSEEVAQ
SEFETAFLNRSLCYFLKQHGIIDEDVEELMDLYTKQCAVEMTCIDLARIGLVFALDGRDPHSGELLMPLDVARICKTFMV
TCGMYNASGEFAIKIGIPAKSGVSGGILAAVPGRCGIGIFGPALDDKGNSLTGVKLLERLSKTYSLSIF
>Mature_308_residues
PVYNKEELVRFVEEAKQYARYGKVADYIPALGKANPNELSIAVYTADGKVVDAGDVTVKVTLQSISKILALALVLIDRGE
DEVFRKVGMEPTGDPFNSIAKLEEVQPSKPLNPMINAGALAVTHMIRGRSVEERLERLLAFIRRLAGNEQITYSEEVAQS
EFETAFLNRSLCYFLKQHGIIDEDVEELMDLYTKQCAVEMTCIDLARIGLVFALDGRDPHSGELLMPLDVARICKTFMVT
CGMYNASGEFAIKIGIPAKSGVSGGILAAVPGRCGIGIFGPALDDKGNSLTGVKLLERLSKTYSLSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=290, Percent_Identity=38.6206896551724, Blast_Score=197, Evalue=8e-51,
Organism=Homo sapiens, GI20336214, Length=302, Percent_Identity=35.0993377483444, Blast_Score=181, Evalue=9e-46,
Organism=Escherichia coli, GI1787804, Length=287, Percent_Identity=42.1602787456446, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1786693, Length=287, Percent_Identity=41.4634146341463, Blast_Score=223, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17532727, Length=290, Percent_Identity=38.2758620689655, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17507019, Length=290, Percent_Identity=35.8620689655172, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI193204073, Length=310, Percent_Identity=32.5806451612903, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI193204075, Length=312, Percent_Identity=32.3717948717949, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI281363241, Length=294, Percent_Identity=35.3741496598639, Blast_Score=181, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24653162, Length=294, Percent_Identity=35.3741496598639, Blast_Score=181, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24653164, Length=294, Percent_Identity=35.3741496598639, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24653156, Length=294, Percent_Identity=35.3741496598639, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI116008307, Length=294, Percent_Identity=35.3741496598639, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI281363239, Length=294, Percent_Identity=35.3741496598639, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24653158, Length=294, Percent_Identity=35.3741496598639, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24653166, Length=294, Percent_Identity=35.3741496598639, Blast_Score=181, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_GEOTN (A4IPX2)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126121.1
- ProteinModelPortal:   A4IPX2
- SMR:   A4IPX2
- STRING:   A4IPX2
- GeneID:   4966952
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_2024
- NMPDR:   fig|420246.5.peg.1938
- eggNOG:   COG2066
- HOGENOM:   HBG512335
- OMA:   FNPLINA
- PhylomeDB:   A4IPX2
- ProtClustDB:   PRK00971
- BioCyc:   GTHE420246:GTNG_2024-MONOMER
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 33774; Mature: 33642

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVYNKEELVRFVEEAKQYARYGKVADYIPALGKANPNELSIAVYTADGKVVDAGDVTVK
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEECCCCEEECCCEEEE
VTLQSISKILALALVLIDRGEDEVFRKVGMEPTGDPFNSIAKLEEVQPSKPLNPMINAGA
EEHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHH
LAVTHMIRGRSVEERLERLLAFIRRLAGNEQITYSEEVAQSEFETAFLNRSLCYFLKQHG
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
IIDEDVEELMDLYTKQCAVEMTCIDLARIGLVFALDGRDPHSGELLMPLDVARICKTFMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCEEEHHHHHHHHHHHHH
TCGMYNASGEFAIKIGIPAKSGVSGGILAAVPGRCGIGIFGPALDDKGNSLTGVKLLERL
HHCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHH
SKTYSLSIF
HHHHEEECC
>Mature Secondary Structure 
PVYNKEELVRFVEEAKQYARYGKVADYIPALGKANPNELSIAVYTADGKVVDAGDVTVK
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEECCCCEEECCCEEEE
VTLQSISKILALALVLIDRGEDEVFRKVGMEPTGDPFNSIAKLEEVQPSKPLNPMINAGA
EEHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHH
LAVTHMIRGRSVEERLERLLAFIRRLAGNEQITYSEEVAQSEFETAFLNRSLCYFLKQHG
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
IIDEDVEELMDLYTKQCAVEMTCIDLARIGLVFALDGRDPHSGELLMPLDVARICKTFMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCEEEHHHHHHHHHHHHH
TCGMYNASGEFAIKIGIPAKSGVSGGILAAVPGRCGIGIFGPALDDKGNSLTGVKLLERL
HHCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHH
SKTYSLSIF
HHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA