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The map label for this gene is opuD [H]

Identifier: 138894829

GI number: 138894829

Start: 1231566

End: 1233050

Strand: Reverse

Name: opuD [H]

Synonym: GTNG_1163

Alternate gene names: 138894829

Gene position: 1233050-1231566 (Counterclockwise)

Preceding gene: 138894841

Following gene: 138894816

Centisome position: 34.73

GC content: 50.44

Gene sequence:

>1485_bases
GTGATTGCCATTGTGTTTATTATTTGGGGAGTCGTTCCGGAGTCTTTGCTGCCACGCTACAATTTAAAGGCGGTCAGCAG
CGCGGTGCACTCGTTTCTGATCGATAAATTCGGCTGGTTTTATTTGCTTAGCGCTTCGTTGTTTTTAGCGTTTTGTTTGT
TTCTCATTTTTTCCCGCTATGGGAATATCCGTCTCGGCCGTGACGGAGAAGAACCGGAATACAGCTATATGACATGGTTT
GCTATGCTGTTTAGCGCCGGAATGGGAATCGGGTTAGTGTTTTGGGGAGTGGCTGAACCGGTGTCCCACTATTACACGCC
GCCAACAGGGGAAGGGGCAACGGCGGAAGCGGCCCGTTTGGCGATGCGCTACTCATTTTTTCATTGGGGGCTACATCCAT
GGGCGATCTACGGCATCCTTGCCTTGGCGCTCGCTTACTTCCAGTTTCGCAAGCAGGAAGCCGGCATCATTAGCCGCACA
CTGCGCCCGCTGTTTGGCGCGCGGACAGAGGGTGGCCTCGGCATCGCTGTTGATACATTAGCCGTATATGCAACGGTTTT
TGGCGTCGCCACTTCATTAGGATTGGGAGCCATTCAAATCGGCGGGGGGTTGCATCAGCTGTTTCCTGGCGTTCCGAACA
GCTTTTCGACGCAATTGCTCATCATTGCGGTCGTCACTGTGCTGTTTATGCTCTCAGCGCAGAGCGGTCTCAACAAAGGA
ATAAAATTGTTGAGCAACCTTAATATTGCACTCGCATTGCTGCTCATGTTTTTCATGCTGTTTGCCGGCCCAACGAATTT
TATTATGGATGTGTTCACAGCGACGATCGGAACGTACTTACAAAACCTCCCGTCGATGAGTTTCCGGCTCAATCCGTTTG
AACAAAATGATTGGCCGAAAGTATGGACCGTTTTTTATTGGGCGTGGTGGATCGCGTGGGCGCCGTTTGTGGGAACGTTT
ATCGCTCGCATTTCCCGTGGACGCACGATCCGTGAATTTATGATCGGTGTCTTGGCGGTTCCAACGATTTTCAGCGCCCT
CTGGTTTTCCGTTTTTGGCGGTTCGGCCCTTTATCTGGAACAGTTCCAACATGCCGGCATTGGTGAAGTGATGAATGAAA
AAGGAATGGAGACAGCCTTGTTCTTTACATTCGAACATTTCCCGCTCTCAACGCTGCTTTCAGGAATCGCTATTTTGCTC
ATTTGTACGTTTTTTGTCACATCGGCGGACTCGGCAACGTTTGTGCTCGGCATGCAGACGACCAACGGCAGCCTAAACCC
GCCAAACTCGGTCAAATTCATCTGGGGCGTTATCCAATCAGCGACCGCGGCCATCCTCCTTTTTGTAGGTGGCCTTGAAT
CGCTGCAGACAGCGTCCATCATCGCTGCGTTTCCGTTTGCGATCATCATGATCTTGATCGTTCTATCTCTTATCCGTTCA
TTCCAGCAAGAAGTGACGCGAAAAGCGAAAAAACCTATCCAATAA

Upstream 100 bases:

>100_bases
CCCCCCAAAACCGCTAACATGGTTCCCATCATATCAGCACATAATAAGAATAAGGAGGAGAGAAATGAAGAAAACAACAG
CCATCTTTTGGATCTCGATT

Downstream 100 bases:

>100_bases
AATGACCAAAGGTGTCCCTCAAGCAACGGGACACCTTTTCTTATGATGGGATGGATGAAATGATTGACAGTCCTTATGAT
TCCCTCAGTTCTGTCGATCA

Product: glycine betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MIAIVFIIWGVVPESLLPRYNLKAVSSAVHSFLIDKFGWFYLLSASLFLAFCLFLIFSRYGNIRLGRDGEEPEYSYMTWF
AMLFSAGMGIGLVFWGVAEPVSHYYTPPTGEGATAEAARLAMRYSFFHWGLHPWAIYGILALALAYFQFRKQEAGIISRT
LRPLFGARTEGGLGIAVDTLAVYATVFGVATSLGLGAIQIGGGLHQLFPGVPNSFSTQLLIIAVVTVLFMLSAQSGLNKG
IKLLSNLNIALALLLMFFMLFAGPTNFIMDVFTATIGTYLQNLPSMSFRLNPFEQNDWPKVWTVFYWAWWIAWAPFVGTF
IARISRGRTIREFMIGVLAVPTIFSALWFSVFGGSALYLEQFQHAGIGEVMNEKGMETALFFTFEHFPLSTLLSGIAILL
ICTFFVTSADSATFVLGMQTTNGSLNPPNSVKFIWGVIQSATAAILLFVGGLESLQTASIIAAFPFAIIMILIVLSLIRS
FQQEVTRKAKKPIQ

Sequences:

>Translated_494_residues
MIAIVFIIWGVVPESLLPRYNLKAVSSAVHSFLIDKFGWFYLLSASLFLAFCLFLIFSRYGNIRLGRDGEEPEYSYMTWF
AMLFSAGMGIGLVFWGVAEPVSHYYTPPTGEGATAEAARLAMRYSFFHWGLHPWAIYGILALALAYFQFRKQEAGIISRT
LRPLFGARTEGGLGIAVDTLAVYATVFGVATSLGLGAIQIGGGLHQLFPGVPNSFSTQLLIIAVVTVLFMLSAQSGLNKG
IKLLSNLNIALALLLMFFMLFAGPTNFIMDVFTATIGTYLQNLPSMSFRLNPFEQNDWPKVWTVFYWAWWIAWAPFVGTF
IARISRGRTIREFMIGVLAVPTIFSALWFSVFGGSALYLEQFQHAGIGEVMNEKGMETALFFTFEHFPLSTLLSGIAILL
ICTFFVTSADSATFVLGMQTTNGSLNPPNSVKFIWGVIQSATAAILLFVGGLESLQTASIIAAFPFAIIMILIVLSLIRS
FQQEVTRKAKKPIQ
>Mature_494_residues
MIAIVFIIWGVVPESLLPRYNLKAVSSAVHSFLIDKFGWFYLLSASLFLAFCLFLIFSRYGNIRLGRDGEEPEYSYMTWF
AMLFSAGMGIGLVFWGVAEPVSHYYTPPTGEGATAEAARLAMRYSFFHWGLHPWAIYGILALALAYFQFRKQEAGIISRT
LRPLFGARTEGGLGIAVDTLAVYATVFGVATSLGLGAIQIGGGLHQLFPGVPNSFSTQLLIIAVVTVLFMLSAQSGLNKG
IKLLSNLNIALALLLMFFMLFAGPTNFIMDVFTATIGTYLQNLPSMSFRLNPFEQNDWPKVWTVFYWAWWIAWAPFVGTF
IARISRGRTIREFMIGVLAVPTIFSALWFSVFGGSALYLEQFQHAGIGEVMNEKGMETALFFTFEHFPLSTLLSGIAILL
ICTFFVTSADSATFVLGMQTTNGSLNPPNSVKFIWGVIQSATAAILLFVGGLESLQTASIIAAFPFAIIMILIVLSLIRS
FQQEVTRKAKKPIQ

Specific function: High-affinity uptake of glycine betaine [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=459, Percent_Identity=39.8692810457516, Blast_Score=352, Evalue=4e-98,
Organism=Escherichia coli, GI1786224, Length=468, Percent_Identity=33.1196581196581, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1788102, Length=446, Percent_Identity=32.0627802690583, Blast_Score=220, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 54545; Mature: 54545

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8752321; 9387221; 9384377 [H]