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The map label for this gene is nusA [H]

Identifier: 138894780

GI number: 138894780

Start: 1177834

End: 1178985

Strand: Direct

Name: nusA [H]

Synonym: GTNG_1114

Alternate gene names: 138894780

Gene position: 1177834-1178985 (Clockwise)

Preceding gene: 138894779

Following gene: 138894781

Centisome position: 33.18

GC content: 53.99

Gene sequence:

>1152_bases
ATGAACACGCAGTTGCTTGAGGCGTTAGCCGATCTGATGCGGGAAAAGGGCATCAGCAAAGAAGTCATCATGGAAGCGAT
TGAAGCAGCGCTCGTTTCAGCGTATAAACGCAACTTCGGCCAGGCGCAAAACGTGCGCGTCGATTTAAACATGGATACAG
GAACGATCCGGGTGCTCGCTCGCAAGGATGTCGTTGAAGAGGTAACCGACCCGCGCCTTGAAATTTCTCTTGAGGAGGCG
CAGCGGCTCAATCCGAACTATCAAATCGGTGATGTCGTCGAACTGGAAGTGACGCCGCGTGATTTCGGCCGCATCGCGGC
GCAGACGGCGAAACAAGTCGTTACCCAGCGTGTGCGCGAAGCGGAGCGGAGCATTATTTACGCTGAATTCGTCGACCGTG
AAGAAGACATTATGACCGGCATCGTCCAGCGCATTGACCCTCGCTTTGTCTATGTCAGCCTCGGCAAAGCGGAAGCGCTC
TTGCCGGCGAATGAGCAAATGCCGAACGAAACGTACAAACCGCACGATCGGCTGAAAGTATACATTACGAAAGTGGAAAA
AACGACAAAAGGGCCGCAAATTTTCGTCTCCCGCACTCATCCGGGTTTGTTAAAGCGGCTGTTTGAGCTTGAAGTGCCGG
AAATTTACGATGGCACGGTTGAAATTAAATCGATTGCCCGTGAAGCCGGCGACCGTTCGAAAATTTCCGTTCATTCCGAC
AATCCGGAAGTCGATCCGGTTGGTGCCTGCGTCGGGCCGAAGGGGCAGCGTGTACAGGCGATCGTCGATGAGCTGCACGG
CGAAAAAATCGATATCGTCCGTTGGTCGGCTGATCCGGTCGAATTTGTCGCCAACGCGCTAAGTCCGGCCAAAGTGCTGC
GCGTCATCGTGAATGAAGAACAAAAGGCGACGACCGTCATTGTCCCGGACTACCAGCTGTCGCTTGCCATCGGCAAGCGA
GGCCAAAACGCCCGGCTGGCCGCGAAATTGACTGGCTGGAAAATTGACATTAAAAGCGAATCAGAAGCGCGGGAAATGGG
CATCGACCCGCATGCACCATCCACTTCGCTTGATTTCGACGGCGTGACGGCCGATAATGAAAATAGTGATGAGAGCGGTC
AACCATTTGATGCAACGGCGGAAATCGAGTGA

Upstream 100 bases:

>100_bases
CCGCGGGCGGCAAAAAACAGTCGCCATTCCGTATGAAAAAGTGGCGAGCGCAAGACTAGCCGTCATCTTCTTCTAATAAT
AAAAGGGGGATTTTCGTTTC

Downstream 100 bases:

>100_bases
GGGGGAATGAAGATGGCAGCGCAAAAGAAAATTCCGTTGCGCAAATGCGTCGTCACCGGAGAGATGAAGCCGAAACGGGA
AATGGTGCGCATCGTCCGCT

Product: transcription elongation factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MNTQLLEALADLMREKGISKEVIMEAIEAALVSAYKRNFGQAQNVRVDLNMDTGTIRVLARKDVVEEVTDPRLEISLEEA
QRLNPNYQIGDVVELEVTPRDFGRIAAQTAKQVVTQRVREAERSIIYAEFVDREEDIMTGIVQRIDPRFVYVSLGKAEAL
LPANEQMPNETYKPHDRLKVYITKVEKTTKGPQIFVSRTHPGLLKRLFELEVPEIYDGTVEIKSIAREAGDRSKISVHSD
NPEVDPVGACVGPKGQRVQAIVDELHGEKIDIVRWSADPVEFVANALSPAKVLRVIVNEEQKATTVIVPDYQLSLAIGKR
GQNARLAAKLTGWKIDIKSESEAREMGIDPHAPSTSLDFDGVTADNENSDESGQPFDATAEIE

Sequences:

>Translated_383_residues
MNTQLLEALADLMREKGISKEVIMEAIEAALVSAYKRNFGQAQNVRVDLNMDTGTIRVLARKDVVEEVTDPRLEISLEEA
QRLNPNYQIGDVVELEVTPRDFGRIAAQTAKQVVTQRVREAERSIIYAEFVDREEDIMTGIVQRIDPRFVYVSLGKAEAL
LPANEQMPNETYKPHDRLKVYITKVEKTTKGPQIFVSRTHPGLLKRLFELEVPEIYDGTVEIKSIAREAGDRSKISVHSD
NPEVDPVGACVGPKGQRVQAIVDELHGEKIDIVRWSADPVEFVANALSPAKVLRVIVNEEQKATTVIVPDYQLSLAIGKR
GQNARLAAKLTGWKIDIKSESEAREMGIDPHAPSTSLDFDGVTADNENSDESGQPFDATAEIE
>Mature_383_residues
MNTQLLEALADLMREKGISKEVIMEAIEAALVSAYKRNFGQAQNVRVDLNMDTGTIRVLARKDVVEEVTDPRLEISLEEA
QRLNPNYQIGDVVELEVTPRDFGRIAAQTAKQVVTQRVREAERSIIYAEFVDREEDIMTGIVQRIDPRFVYVSLGKAEAL
LPANEQMPNETYKPHDRLKVYITKVEKTTKGPQIFVSRTHPGLLKRLFELEVPEIYDGTVEIKSIAREAGDRSKISVHSD
NPEVDPVGACVGPKGQRVQAIVDELHGEKIDIVRWSADPVEFVANALSPAKVLRVIVNEEQKATTVIVPDYQLSLAIGKR
GQNARLAAKLTGWKIDIKSESEAREMGIDPHAPSTSLDFDGVTADNENSDESGQPFDATAEIE

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=372, Percent_Identity=39.247311827957, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 42611; Mature: 42611

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQLLEALADLMREKGISKEVIMEAIEAALVSAYKRNFGQAQNVRVDLNMDTGTIRVLA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEE
RKDVVEEVTDPRLEISLEEAQRLNPNYQIGDVVELEVTPRDFGRIAAQTAKQVVTQRVRE
HHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
AERSIIYAEFVDREEDIMTGIVQRIDPRFVYVSLGKAEALLPANEQMPNETYKPHDRLKV
HHHHEEEHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCCEEE
YITKVEKTTKGPQIFVSRTHPGLLKRLFELEVPEIYDGTVEIKSIAREAGDRSKISVHSD
EEEEEECCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECC
NPEVDPVGACVGPKGQRVQAIVDELHGEKIDIVRWSADPVEFVANALSPAKVLRVIVNEE
CCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHCCC
QKATTVIVPDYQLSLAIGKRGQNARLAAKLTGWKIDIKSESEAREMGIDPHAPSTSLDFD
CCCEEEEECCCEEEEEECCCCCCCEEEEEEECEEEEECCCCHHHHCCCCCCCCCCCCCCC
GVTADNENSDESGQPFDATAEIE
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNTQLLEALADLMREKGISKEVIMEAIEAALVSAYKRNFGQAQNVRVDLNMDTGTIRVLA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEE
RKDVVEEVTDPRLEISLEEAQRLNPNYQIGDVVELEVTPRDFGRIAAQTAKQVVTQRVRE
HHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
AERSIIYAEFVDREEDIMTGIVQRIDPRFVYVSLGKAEALLPANEQMPNETYKPHDRLKV
HHHHEEEHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCCEEE
YITKVEKTTKGPQIFVSRTHPGLLKRLFELEVPEIYDGTVEIKSIAREAGDRSKISVHSD
EEEEEECCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECC
NPEVDPVGACVGPKGQRVQAIVDELHGEKIDIVRWSADPVEFVANALSPAKVLRVIVNEE
CCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHCCC
QKATTVIVPDYQLSLAIGKRGQNARLAAKLTGWKIDIKSESEAREMGIDPHAPSTSLDFD
CCCEEEEECCCEEEEEECCCCCCCEEEEEEECEEEEECCCCHHHHCCCCCCCCCCCCCCC
GVTADNENSDESGQPFDATAEIE
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]