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The map label for this gene is gufA [H]

Identifier: 138894515

GI number: 138894515

Start: 919906

End: 920637

Strand: Reverse

Name: gufA [H]

Synonym: GTNG_0845

Alternate gene names: 138894515

Gene position: 920637-919906 (Counterclockwise)

Preceding gene: 138894518

Following gene: 138894509

Centisome position: 25.93

GC content: 48.63

Gene sequence:

>732_bases
ATGAACCAGGTGTTGGTCGGCAGCGTGCTTTCTGCCTTATCGACAGGACTTGGCGCCGTGCCGATTTTGTTTTTGGCTAA
ATCACTCACCCACCGCTGGCGTGATATACTGCTAGCGTTTTCCGCTGGCATTATGATGGCAGCCTCGATGGAAAGTCTCA
TTCCCGAAGCGTTAAAAACCGGCGGCTTGGGAGCACTCGTAATCGGCCTGGCGGCAGGTGTGCTCATCTTAACGTTGCTC
GAGATGACTGTTCCCCATATCGACTTGGAACATACAAAACATGGCTTACAGTTTGACGAAAAAGCGATGCTCATCATCGC
TGCCATTACGATGCACAATCTTCCTGAAGGGTTGTCCGTTGGGGTCAGCTACGCATCCGATGCCGCGACGACCGGCAATT
TGATCGCATTGGCCATCGGTTTGCAAAACGCGCCGGAAGGATTTTTAGTCGCCTTATTTTTAGTTCATCAACAAATTAGT
CGCTTGAAAGCATTTCTTATTGCCACGTTGACAGGAGCGGTCGAAATCGTCACATCGCTGCTCGGTTTTTATTTAACCTC
CCTCTTCCGCGGTTTAGTCCCGTACGGATTGGCGTTTGCCGCTGGGGCTATGCTGTTTATTATTTATAAAGAGCTCATTC
CCGAAAGCCATGGCGATGGAAACGAACGGACATCGACATATGCATTTATTATCGGCATTGTGTTCATGATTTTTTTAACG
CAATCGTTTTGA

Upstream 100 bases:

>100_bases
TTCGTTATGATAATTTATTATATGAAGGCGCTTGGGCGATTGTCACATTTATATGATCATTGCATATGAAAAAGTAAAGG
ATGATGAGGGGGGGAATTGA

Downstream 100 bases:

>100_bases
TCAAAAAAAGAGAGGGTGCCCTAAAGACAAACGGGACACCCCTTTTTATATGCGCTTTTATGAAGACGATGGAAAGCAGG
CGTTTTCCATGTCTACCTAG

Product: GufA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNQVLVGSVLSALSTGLGAVPILFLAKSLTHRWRDILLAFSAGIMMAASMESLIPEALKTGGLGALVIGLAAGVLILTLL
EMTVPHIDLEHTKHGLQFDEKAMLIIAAITMHNLPEGLSVGVSYASDAATTGNLIALAIGLQNAPEGFLVALFLVHQQIS
RLKAFLIATLTGAVEIVTSLLGFYLTSLFRGLVPYGLAFAAGAMLFIIYKELIPESHGDGNERTSTYAFIIGIVFMIFLT
QSF

Sequences:

>Translated_243_residues
MNQVLVGSVLSALSTGLGAVPILFLAKSLTHRWRDILLAFSAGIMMAASMESLIPEALKTGGLGALVIGLAAGVLILTLL
EMTVPHIDLEHTKHGLQFDEKAMLIIAAITMHNLPEGLSVGVSYASDAATTGNLIALAIGLQNAPEGFLVALFLVHQQIS
RLKAFLIATLTGAVEIVTSLLGFYLTSLFRGLVPYGLAFAAGAMLFIIYKELIPESHGDGNERTSTYAFIIGIVFMIFLT
QSF
>Mature_243_residues
MNQVLVGSVLSALSTGLGAVPILFLAKSLTHRWRDILLAFSAGIMMAASMESLIPEALKTGGLGALVIGLAAGVLILTLL
EMTVPHIDLEHTKHGLQFDEKAMLIIAAITMHNLPEGLSVGVSYASDAATTGNLIALAIGLQNAPEGFLVALFLVHQQIS
RLKAFLIATLTGAVEIVTSLLGFYLTSLFRGLVPYGLAFAAGAMLFIIYKELIPESHGDGNERTSTYAFIIGIVFMIFLT
QSF

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=146, Percent_Identity=39.041095890411, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI229577422, Length=146, Percent_Identity=39.041095890411, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17507805, Length=309, Percent_Identity=27.831715210356, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24652846, Length=163, Percent_Identity=34.9693251533742, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 25787; Mature: 25787

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQVLVGSVLSALSTGLGAVPILFLAKSLTHRWRDILLAFSAGIMMAASMESLIPEALKT
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLGALVIGLAAGVLILTLLEMTVPHIDLEHTKHGLQFDEKAMLIIAAITMHNLPEGLSV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHH
GVSYASDAATTGNLIALAIGLQNAPEGFLVALFLVHQQISRLKAFLIATLTGAVEIVTSL
HHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFYLTSLFRGLVPYGLAFAAGAMLFIIYKELIPESHGDGNERTSTYAFIIGIVFMIFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QSF
CCC
>Mature Secondary Structure
MNQVLVGSVLSALSTGLGAVPILFLAKSLTHRWRDILLAFSAGIMMAASMESLIPEALKT
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLGALVIGLAAGVLILTLLEMTVPHIDLEHTKHGLQFDEKAMLIIAAITMHNLPEGLSV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHH
GVSYASDAATTGNLIALAIGLQNAPEGFLVALFLVHQQISRLKAFLIATLTGAVEIVTSL
HHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFYLTSLFRGLVPYGLAFAAGAMLFIIYKELIPESHGDGNERTSTYAFIIGIVFMIFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QSF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]