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The map label for this gene is mtnB

Identifier: 138894513

GI number: 138894513

Start: 918556

End: 919191

Strand: Direct

Name: mtnB

Synonym: GTNG_0843

Alternate gene names: 138894513

Gene position: 918556-919191 (Clockwise)

Preceding gene: 138894512

Following gene: 138894514

Centisome position: 25.87

GC content: 49.69

Gene sequence:

>636_bases
ATGAGCATTATGTTGAAAAAATGGAATGAACTTGCGGAAGTGAAAGCTGAGCTCGCCGCCCGTGATTGGTTTTTTGCGAC
AAGCGGCAATTTGTCGCTCAAAGTGACCGATGCCCCGTTGACGTTCCTTGTCACCGCAAGCGGCAAAGATAAACGGAAGC
AGACAAGCGAAGATTTTCTGCTCATCGACGCCGATGGAAAACCGGTGGAAGACACGCATTTGAAGCCGTCGGCGGAGACG
CTTTTGCACGTCGAGGTTTATCGGCGGACGAATGCCGGCTGCGTCTTGCACGTTCATACGGTCGACAATAACATCATTTC
CGACGTGTACGCTCAAAACAGGGAAGCAGTCTTTTCCGGTCAAGAAATTATTAAGGCGTTTGGCATCTGGGAAGAAAATG
CGGAAGTGCGCATTCCGATCATTGACAATTACGCCGACATCCCGACTTTGGCTAATGAATTTGCCAAGCATATCGACGGT
GATACGGGGGCTGTTTTGATCCAAAACCACGGTATTACCGTTTGGGGTCGTGATGCGTTTGAAGCGAAAAAACATTTGGA
AGCGTGGGAGTTTTTGTTCAGCTGGCAGGTGAAGCGGCTATTATTACAACGGGCCGCTGTGCCGCTAGTTGACTAA

Upstream 100 bases:

>100_bases
ATTTCTTGCTTAAGAAATGTCAAGAGCTCGATTTGCCGCATGCACCGTTTACGACATTTTTTGATGTGGTGGATCATTTG
CAGCGGCTGGAGGTGATCGC

Downstream 100 bases:

>100_bases
CCGATATATTTTTAAAGGGGGATTTGACGATGGCAGTGATTAAAGTGAAAAAAACGGGCCAAGTGATTGAAGGGGAAGAC
AATGTCCGCGCTTTTTTAAA

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSIMLKKWNELAEVKAELAARDWFFATSGNLSLKVTDAPLTFLVTASGKDKRKQTSEDFLLIDADGKPVEDTHLKPSAET
LLHVEVYRRTNAGCVLHVHTVDNNIISDVYAQNREAVFSGQEIIKAFGIWEENAEVRIPIIDNYADIPTLANEFAKHIDG
DTGAVLIQNHGITVWGRDAFEAKKHLEAWEFLFSWQVKRLLLQRAAVPLVD

Sequences:

>Translated_211_residues
MSIMLKKWNELAEVKAELAARDWFFATSGNLSLKVTDAPLTFLVTASGKDKRKQTSEDFLLIDADGKPVEDTHLKPSAET
LLHVEVYRRTNAGCVLHVHTVDNNIISDVYAQNREAVFSGQEIIKAFGIWEENAEVRIPIIDNYADIPTLANEFAKHIDG
DTGAVLIQNHGITVWGRDAFEAKKHLEAWEFLFSWQVKRLLLQRAAVPLVD
>Mature_210_residues
SIMLKKWNELAEVKAELAARDWFFATSGNLSLKVTDAPLTFLVTASGKDKRKQTSEDFLLIDADGKPVEDTHLKPSAETL
LHVEVYRRTNAGCVLHVHTVDNNIISDVYAQNREAVFSGQEIIKAFGIWEENAEVRIPIIDNYADIPTLANEFAKHIDGD
TGAVLIQNHGITVWGRDAFEAKKHLEAWEFLFSWQVKRLLLQRAAVPLVD

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily

Homologues:

Organism=Homo sapiens, GI166235186, Length=213, Percent_Identity=27.2300469483568, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322484, Length=204, Percent_Identity=28.4313725490196, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNB_GEOTN (A4ILL7)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001124966.1
- ProteinModelPortal:   A4ILL7
- STRING:   A4ILL7
- GeneID:   4965786
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_0843
- NMPDR:   fig|420246.5.peg.810
- eggNOG:   COG0235
- HOGENOM:   HBG337716
- OMA:   EFLFECE
- PhylomeDB:   A4ILL7
- ProtClustDB:   PRK06754
- BioCyc:   GTHE420246:GTNG_0843-MONOMER
- HAMAP:   MF_01677
- InterPro:   IPR001303
- InterPro:   IPR017714
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR03328

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.2.1.109

Molecular weight: Translated: 23755; Mature: 23624

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIMLKKWNELAEVKAELAARDWFFATSGNLSLKVTDAPLTFLVTASGKDKRKQTSEDFL
CCCHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCEEEEEECCCCCCCCCCCCCEE
LIDADGKPVEDTHLKPSAETLLHVEVYRRTNAGCVLHVHTVDNNIISDVYAQNREAVFSG
EEECCCCCCCCCCCCCCHHHEEEEEEEEECCCCEEEEEEECCCHHHHHHHHCCCHHHCCH
QEIIKAFGIWEENAEVRIPIIDNYADIPTLANEFAKHIDGDTGAVLIQNHGITVWGRDAF
HHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCEEEEECHHH
EAKKHLEAWEFLFSWQVKRLLLQRAAVPLVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SIMLKKWNELAEVKAELAARDWFFATSGNLSLKVTDAPLTFLVTASGKDKRKQTSEDFL
CCHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCEEEEEECCCCCCCCCCCCCEE
LIDADGKPVEDTHLKPSAETLLHVEVYRRTNAGCVLHVHTVDNNIISDVYAQNREAVFSG
EEECCCCCCCCCCCCCCHHHEEEEEEEEECCCCEEEEEEECCCHHHHHHHHCCCHHHCCH
QEIIKAFGIWEENAEVRIPIIDNYADIPTLANEFAKHIDGDTGAVLIQNHGITVWGRDAF
HHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCEEEEECHHH
EAKKHLEAWEFLFSWQVKRLLLQRAAVPLVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA