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The map label for this gene is mtnE [H]

Identifier: 138894510

GI number: 138894510

Start: 915210

End: 916385

Strand: Direct

Name: mtnE [H]

Synonym: GTNG_0840

Alternate gene names: 138894510

Gene position: 915210-916385 (Clockwise)

Preceding gene: 138894503

Following gene: 138894511

Centisome position: 25.78

GC content: 53.91

Gene sequence:

>1176_bases
ATGACGACCGAATTTCCTTTTTCCGAACTGCTTGAACAGTTGCCGAAGCAATTTTTTGCTTCGCTTGTCGCCAAAGTGGG
AGCGAAAATAAAGGCCGGGCACGATGTCATTAATTTAGGGCAAGGCAATCCGGATCAGCCGACGCCTGGCCATATTGTTG
AGGCGATGCAACAGGCAGTGGCCAATCCAAAATACCATAAATATTCGCCGTTTCAAGGTTACTCATTTTTGAAAAAAGCA
GTCGCTGCGTTTTATGCGCGTGAGTACGGGGTTGATGTGGATCCAACCCGCGAGGTAGCCATTTTGTTTGGCGGTAAGGC
TGGTCTTGTTGAGCTGCCGCTTTGCCTCGTCAATCCGGGCGATGTGGTGCTTGTCCCGGATCCGGGCTATCCGGACTACT
GGTCCGGGATCGCGCTCGCCCGCGCACGGATGGAAATGATGCCGCTTATCGCCGAGCAGCAATTTTTGCCTGATTACAGT
GCCATTCCGGCAGCGATCGCTGATCAGGCCAAACTGATGTTTTTGAACTATCCGAACAACCCGACCGGGGCGACGGCGAC
GAAAGAGTTTTTTGCTGAAACAGTGGCGTTCGCCGCTAAGTACGGCATTGCTGTTGTGCATGATTTCGCCTACGGGGCGA
TCGGTTTTGATGGCAAAAAGCCGGTCAGCTTTCTCGAAGTTGATGGGGCGAAAGAGGTCGGTGTTGAAATTTACACGTTT
TCCAAAACGTACAATATGGCCGGTTGGCGTGTCGCGTTTGCCGTTGGCAATGAACAGATCATCCGGGCGATTGAGTTGTT
GCAAGATCATTTGTATGTCAGTTTGTTCGGCGCTGTTCAAGAGGCGGCTGCCGCGGCGCTTCTCGGTCCGCAAGATTGCG
TCACGGAGCTCGTCGCATTGTATGAAGCGCGCCGCAATACGTTCATTTCTGCTTTGCACCGCATCGGTTGGGAGGCGCCG
GCACCGTCTGGATCGTTTTTCGCTTGGCTTCCCGTACCGAAAGGATTATCGTCCGCTGAGTTTGCCGACATACTGCTTGA
ACGCGTACACGTGGCGGTCGCTCCGGGCATCGGTTTTGGCAAGCACGGCGAAGGCTATGTGCGCGTTGGTCTGTTGACAG
ATGAGGCGCGTCTTGTCGAAGCAGCTGAACGGATCGGGCGTCTCGGGCTGTTTTGA

Upstream 100 bases:

>100_bases
TTGTTTTTCACCTCAATGAAAAAATTTACTTTACATTTTGCTTTTTACGATATATGATTTTGCACTAGAATTTCAAGAAA
TTTTTGAGAAGGTGTGGGCG

Downstream 100 bases:

>100_bases
AAAAAATGATTGACAACAGCGGCAGAGGCTGTCATAATTCAAAGTACATTTGCCATACTCGACAAAATTGTTTGACAAGT
TCATAAATACGCAATGATTC

Product: transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTTEFPFSELLEQLPKQFFASLVAKVGAKIKAGHDVINLGQGNPDQPTPGHIVEAMQQAVANPKYHKYSPFQGYSFLKKA
VAAFYAREYGVDVDPTREVAILFGGKAGLVELPLCLVNPGDVVLVPDPGYPDYWSGIALARARMEMMPLIAEQQFLPDYS
AIPAAIADQAKLMFLNYPNNPTGATATKEFFAETVAFAAKYGIAVVHDFAYGAIGFDGKKPVSFLEVDGAKEVGVEIYTF
SKTYNMAGWRVAFAVGNEQIIRAIELLQDHLYVSLFGAVQEAAAAALLGPQDCVTELVALYEARRNTFISALHRIGWEAP
APSGSFFAWLPVPKGLSSAEFADILLERVHVAVAPGIGFGKHGEGYVRVGLLTDEARLVEAAERIGRLGLF

Sequences:

>Translated_391_residues
MTTEFPFSELLEQLPKQFFASLVAKVGAKIKAGHDVINLGQGNPDQPTPGHIVEAMQQAVANPKYHKYSPFQGYSFLKKA
VAAFYAREYGVDVDPTREVAILFGGKAGLVELPLCLVNPGDVVLVPDPGYPDYWSGIALARARMEMMPLIAEQQFLPDYS
AIPAAIADQAKLMFLNYPNNPTGATATKEFFAETVAFAAKYGIAVVHDFAYGAIGFDGKKPVSFLEVDGAKEVGVEIYTF
SKTYNMAGWRVAFAVGNEQIIRAIELLQDHLYVSLFGAVQEAAAAALLGPQDCVTELVALYEARRNTFISALHRIGWEAP
APSGSFFAWLPVPKGLSSAEFADILLERVHVAVAPGIGFGKHGEGYVRVGLLTDEARLVEAAERIGRLGLF
>Mature_390_residues
TTEFPFSELLEQLPKQFFASLVAKVGAKIKAGHDVINLGQGNPDQPTPGHIVEAMQQAVANPKYHKYSPFQGYSFLKKAV
AAFYAREYGVDVDPTREVAILFGGKAGLVELPLCLVNPGDVVLVPDPGYPDYWSGIALARARMEMMPLIAEQQFLPDYSA
IPAAIADQAKLMFLNYPNNPTGATATKEFFAETVAFAAKYGIAVVHDFAYGAIGFDGKKPVSFLEVDGAKEVGVEIYTFS
KTYNMAGWRVAFAVGNEQIIRAIELLQDHLYVSLFGAVQEAAAAALLGPQDCVTELVALYEARRNTFISALHRIGWEAPA
PSGSFFAWLPVPKGLSSAEFADILLERVHVAVAPGIGFGKHGEGYVRVGLLTDEARLVEAAERIGRLGLF

Specific function: Catalyzes the formation of methionine from 2-keto-4- methylthiobutyrate (KMTB) (Probable) [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. MtnE subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=408, Percent_Identity=23.7745098039216, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI169881279, Length=408, Percent_Identity=23.7745098039216, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI56713254, Length=316, Percent_Identity=23.4177215189873, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI56713256, Length=316, Percent_Identity=23.4177215189873, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4507369, Length=390, Percent_Identity=23.5897435897436, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788722, Length=374, Percent_Identity=37.1657754010695, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=27.7486910994764, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788627, Length=292, Percent_Identity=26.7123287671233, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=407, Percent_Identity=24.3243243243243, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=407, Percent_Identity=24.3243243243243, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=395, Percent_Identity=23.0379746835443, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=25.2688172043011, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=398, Percent_Identity=21.608040201005, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573069, Length=385, Percent_Identity=21.8181818181818, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646114, Length=385, Percent_Identity=21.8181818181818, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28573067, Length=385, Percent_Identity=21.8181818181818, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28573065, Length=385, Percent_Identity=21.8181818181818, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI18859735, Length=347, Percent_Identity=22.1902017291066, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42364; Mature: 42233

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEFPFSELLEQLPKQFFASLVAKVGAKIKAGHDVINLGQGNPDQPTPGHIVEAMQQAV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEECCCCCCCCCCCCHHHHHHHHHH
ANPKYHKYSPFQGYSFLKKAVAAFYAREYGVDVDPTREVAILFGGKAGLVELPLCLVNPG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEECCEEEECCC
DVVLVPDPGYPDYWSGIALARARMEMMPLIAEQQFLPDYSAIPAAIADQAKLMFLNYPNN
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHCCCCEEEEEECCCC
PTGATATKEFFAETVAFAAKYGIAVVHDFAYGAIGFDGKKPVSFLEVDGAKEVGVEIYTF
CCCCHHHHHHHHHHHHHHHHHCHHEEEHHHHCEECCCCCCCCEEEEECCCHHCCEEEEEE
SKTYNMAGWRVAFAVGNEQIIRAIELLQDHLYVSLFGAVQEAAAAALLGPQDCVTELVAL
ECEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YEARRNTFISALHRIGWEAPAPSGSFFAWLPVPKGLSSAEFADILLERVHVAVAPGIGFG
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEECCCCCC
KHGEGYVRVGLLTDEARLVEAAERIGRLGLF
CCCCCEEEEEEEECHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTEFPFSELLEQLPKQFFASLVAKVGAKIKAGHDVINLGQGNPDQPTPGHIVEAMQQAV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEECCCCCCCCCCCCHHHHHHHHHH
ANPKYHKYSPFQGYSFLKKAVAAFYAREYGVDVDPTREVAILFGGKAGLVELPLCLVNPG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEECCEEEECCC
DVVLVPDPGYPDYWSGIALARARMEMMPLIAEQQFLPDYSAIPAAIADQAKLMFLNYPNN
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHCCCCEEEEEECCCC
PTGATATKEFFAETVAFAAKYGIAVVHDFAYGAIGFDGKKPVSFLEVDGAKEVGVEIYTF
CCCCHHHHHHHHHHHHHHHHHCHHEEEHHHHCEECCCCCCCCEEEEECCCHHCCEEEEEE
SKTYNMAGWRVAFAVGNEQIIRAIELLQDHLYVSLFGAVQEAAAAALLGPQDCVTELVAL
ECEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YEARRNTFISALHRIGWEAPAPSGSFFAWLPVPKGLSSAEFADILLERVHVAVAPGIGFG
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEECCCCCC
KHGEGYVRVGLLTDEARLVEAAERIGRLGLF
CCCCCEEEEEEEECHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]