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The map label for this gene is menC [H]

Identifier: 138894485

GI number: 138894485

Start: 887796

End: 888923

Strand: Direct

Name: menC [H]

Synonym: GTNG_0815

Alternate gene names: 138894485

Gene position: 887796-888923 (Clockwise)

Preceding gene: 138894484

Following gene: 138894488

Centisome position: 25.01

GC content: 51.77

Gene sequence:

>1128_bases
ATGAGGCTTGAAATTGATTACATCATTTTACGTTACTTGCAAATGGAGCTGAAAGCACCGTTTACGACCAGTTTTGGTAC
GTTTCAAACAAAAGAATTTATTTTAGTGGAAGCAGTCGACAGCAACGGTGTCTCAGGATGGGGCGAATCGGTGGCATTTT
CCGCTCCGTGGTATAGTGAGGAAACGGTAAAAACGAACTGGCATATGCTTGAGGATTTTCTTATCCCACTGGCATTTGCT
GAGCCGATCGATCATCCGAGTGAACTATCAAAACGGTTTGGGGCGATCCGCCAAAACCATATGGCGAAAGCCGCGCTCGA
AGGTGCGGTATGGGATTTGTACGCCAAGCGGCTTGGCGTTCCGCTTTATCAGGCATTGGGTGGAACGAAAAGGGAAATTG
AAGTTGGTGTCAGCATCGGCATTCAGCCGACGGTAGATGAGTTGCTTCGGGTTATTGAACGGTATGTAACCCAAGGATAT
CGGCGAATGAAGGTGAAAATCAAGCCGGGCTGGGACGTTGAGGTCATTCGTGAAGTGCGGCGTGTGTTTCCAGACGTGCC
GCTCATGGCAGATGCCAATTCAGCGTACACACTTGCTGATGTGGAGCGGCTGAAAGCACTCGATGAATTCGGACTGATGA
TGATCGAACAACCGCTTGCGGCTGACGATCTCGTTGATCATGCCCAGCTGCAGCCGCTTCTGAAGACGCCGATTTGCCTT
GATGAAAGTATCCGCTCATTCGACGATGCGCGCAAGGCGCTTCATCTTGGCAGTTGTCGCATCATCAATATGAAAATTGG
ACGCATCGGCGGACTGCAGGAGGCAAAACACATTCATGATCTTTGCCGTGAGCACGGCGTTCCGGTTTGGTGCGGTGGCA
TGTTGGAAGCGGGCGTTGGGCGCGCTCACAATATCGCCATTACGACTTTGGAAAACTTCACCCTTCCCGGCGACACAGCG
GCATCTTCCCATTACTGGGAGCGGGATATTATTGTTCCGGAGGTCGAAGTGCATAACGGCTTGATTCGCGTACCGGACGC
CCCGGGTGTCGGTTATGAAGTCGACCGCCGCCAAGTCGAGCGGTACACGCAATTTGCCAAAGTATATCGCCGTTCGCTGC
CGGCATAA

Upstream 100 bases:

>100_bases
GGCTGGGTTGCTATTCATGCCATGCGCGGCGAAGGGGAACCGGTTATGCACTACATATGGGGACGCCGGAATAAGTGGTT
AGGGGAAAAGGGGGAAAGTA

Downstream 100 bases:

>100_bases
AGAAGGAGGCTGACCCTAAAAACCGCTTCTCCTTAAACGGAAAGTATTGATACAAGAAGGATGTCTTGCCGCTTGCAGGA
CATCCTTGCTCGTTGTTCAT

Product: N-acylamino acid racemase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRLEIDYIILRYLQMELKAPFTTSFGTFQTKEFILVEAVDSNGVSGWGESVAFSAPWYSEETVKTNWHMLEDFLIPLAFA
EPIDHPSELSKRFGAIRQNHMAKAALEGAVWDLYAKRLGVPLYQALGGTKREIEVGVSIGIQPTVDELLRVIERYVTQGY
RRMKVKIKPGWDVEVIREVRRVFPDVPLMADANSAYTLADVERLKALDEFGLMMIEQPLAADDLVDHAQLQPLLKTPICL
DESIRSFDDARKALHLGSCRIINMKIGRIGGLQEAKHIHDLCREHGVPVWCGGMLEAGVGRAHNIAITTLENFTLPGDTA
ASSHYWERDIIVPEVEVHNGLIRVPDAPGVGYEVDRRQVERYTQFAKVYRRSLPA

Sequences:

>Translated_375_residues
MRLEIDYIILRYLQMELKAPFTTSFGTFQTKEFILVEAVDSNGVSGWGESVAFSAPWYSEETVKTNWHMLEDFLIPLAFA
EPIDHPSELSKRFGAIRQNHMAKAALEGAVWDLYAKRLGVPLYQALGGTKREIEVGVSIGIQPTVDELLRVIERYVTQGY
RRMKVKIKPGWDVEVIREVRRVFPDVPLMADANSAYTLADVERLKALDEFGLMMIEQPLAADDLVDHAQLQPLLKTPICL
DESIRSFDDARKALHLGSCRIINMKIGRIGGLQEAKHIHDLCREHGVPVWCGGMLEAGVGRAHNIAITTLENFTLPGDTA
ASSHYWERDIIVPEVEVHNGLIRVPDAPGVGYEVDRRQVERYTQFAKVYRRSLPA
>Mature_375_residues
MRLEIDYIILRYLQMELKAPFTTSFGTFQTKEFILVEAVDSNGVSGWGESVAFSAPWYSEETVKTNWHMLEDFLIPLAFA
EPIDHPSELSKRFGAIRQNHMAKAALEGAVWDLYAKRLGVPLYQALGGTKREIEVGVSIGIQPTVDELLRVIERYVTQGY
RRMKVKIKPGWDVEVIREVRRVFPDVPLMADANSAYTLADVERLKALDEFGLMMIEQPLAADDLVDHAQLQPLLKTPICL
DESIRSFDDARKALHLGSCRIINMKIGRIGGLQEAKHIHDLCREHGVPVWCGGMLEAGVGRAHNIAITTLENFTLPGDTA
ASSHYWERDIIVPEVEVHNGLIRVPDAPGVGYEVDRRQVERYTQFAKVYRRSLPA

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081876, Length=196, Percent_Identity=31.6326530612245, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 42310; Mature: 42310

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLEIDYIILRYLQMELKAPFTTSFGTFQTKEFILVEAVDSNGVSGWGESVAFSAPWYSE
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEECCCCCCC
ETVKTNWHMLEDFLIPLAFAEPIDHPSELSKRFGAIRQNHMAKAALEGAVWDLYAKRLGV
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PLYQALGGTKREIEVGVSIGIQPTVDELLRVIERYVTQGYRRMKVKIKPGWDVEVIREVR
HHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHH
RVFPDVPLMADANSAYTLADVERLKALDEFGLMMIEQPLAADDLVDHAQLQPLLKTPICL
HHCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHH
DESIRSFDDARKALHLGSCRIINMKIGRIGGLQEAKHIHDLCREHGVPVWCGGMLEAGVG
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECHHHHHCCC
RAHNIAITTLENFTLPGDTAASSHYWERDIIVPEVEVHNGLIRVPDAPGVGYEVDRRQVE
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCEEECCCCCCCCCHHHHHHHH
RYTQFAKVYRRSLPA
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLEIDYIILRYLQMELKAPFTTSFGTFQTKEFILVEAVDSNGVSGWGESVAFSAPWYSE
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEECCCCCCC
ETVKTNWHMLEDFLIPLAFAEPIDHPSELSKRFGAIRQNHMAKAALEGAVWDLYAKRLGV
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PLYQALGGTKREIEVGVSIGIQPTVDELLRVIERYVTQGYRRMKVKIKPGWDVEVIREVR
HHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHH
RVFPDVPLMADANSAYTLADVERLKALDEFGLMMIEQPLAADDLVDHAQLQPLLKTPICL
HHCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHH
DESIRSFDDARKALHLGSCRIINMKIGRIGGLQEAKHIHDLCREHGVPVWCGGMLEAGVG
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECHHHHHCCC
RAHNIAITTLENFTLPGDTAASSHYWERDIIVPEVEVHNGLIRVPDAPGVGYEVDRRQVE
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCEEECCCCCCCCCHHHHHHHH
RYTQFAKVYRRSLPA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]