Definition Geobacillus thermodenitrificans NG80-2 chromosome, complete genome.
Accession NC_009328
Length 3,550,319

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The map label for this gene is yfnA [H]

Identifier: 138894488

GI number: 138894488

Start: 891329

End: 892744

Strand: Direct

Name: yfnA [H]

Synonym: GTNG_0818

Alternate gene names: 138894488

Gene position: 891329-892744 (Clockwise)

Preceding gene: 138894485

Following gene: 138894489

Centisome position: 25.11

GC content: 50.56

Gene sequence:

>1416_bases
ATGAATTTGTTTCGTAAAAAACCGATTCAGGCGCTTTTAAACGAATCGGGGGCGAAAGGAGCCTCGCTGCGGAAAGAATT
AAGTGCATTCGACTTAACGATGCTTGGCATCGGTGCCATTATCGGAACAGGCATTTTCGTCCTGACCGGGGTGGCAGCGG
CGGAGCATGCCGGTCCAGCGCTCGTTCTTTCGTTTGCTTTATCTGCGTTGGCGTGCGTCTTCGCAGCGCTTTGTTACGCA
GAATTTGCTTCGACCGTACCGGTTTCGGGAAGTGCGTACACATATAGTTATGCTGCGTTCGGTGAACTGATCGCCTGGAT
TTTAGGCTGGGATTTGATTTTAGAGTACGGAGTTGCTTCATCGGCAGTCGCCGCCGGGTGGTCCGGCTATTTCCAAGGGT
TGCTTGCCGGGTTTGGCATTGAGTTGCCGAAGGCACTCACGAGCGCATATGACCCGGAGAAAGGGACAATCATCGATTTG
CCGGCCATTTTCATTGTTTTGTTCATTACGATTTTATTGAACATGGGCGCGAAAAAATCGGCCCGCTTCAATGCGATTAT
CGTTTTCGTAAAAGTGGCTGTCATCTTGCTTTTCTTGGCGGTCGGTGTTTGGTATGTTAAGCCAGAAAACTGGACGCCGT
TTATGCCGTATGGGTTTGCAGGCGTTGCGACCGGAGCCGCGACGGTGTTTTTCGCTTATATCGGGTTTGATGCGGTGTCA
ACAGCGGCGGAAGAAGTGCGCAATCCACAGCGCAATATGCCAATTGGCATCATCGTCTCATTGCTTGTTTGCACGTTATT
GTATATCGCCGTTTCGCTCGTGTTGACAGGCATCGTTCCATACGACCAATTGAACGTGAAAAACCCGGTGGCGTTCGCAT
TAAGCTACATCCAGCAAGACTGGGTCGCTGGCTTTATTTCGCTCGGAGCGATTGCTGGCATTACGACGGTGTTGCTCGTC
ATGCTTTACGGGCAGACGCGCCTCTTTTATGCGATCAGTCGCGACGGCTTATTGCCAAAAGTATTTGCCCGCATTAGCCC
GACCCGCCAAATACCGTATGTTAACACATGGCTGACAGGTGCAGCTGTTTCGGTATTTGCCGGTGTCATCCCGTTGAACA
AACTGGCGGAACTGACGAACATTGGAACGCTCTTTGCCTTTATTACTGTTTCAATTGGTGTTCTCGTTTTGCGCAAAACA
CAGCCAGACTTAAAGCGGGCGTTCCGTGTTCCGTTCGTGCCGTTCGTCCCGATTTTAGCGGTCTTGTTCTGCGGCTACTT
AGTTCTTCAGCTCCCAGCAACGACATGGATCGGTTTTGTTTCCTGGTTGTTAATCGGCTTGGTGATTTACTTTGCTTACG
GGCGTAAGCATAGCGTGCTCAATGAAACGGCTGAGAGCGAAGAAAAAGTTGGCTGA

Upstream 100 bases:

>100_bases
TTCGCACTTTACAAAAAAACAAGGATCATGTAGAATGCTAACTGTGTTCATTGATTAAATTCGACATTTTTCTACAAAAA
GCGACAAGGAGAGACATTTG

Downstream 100 bases:

>100_bases
TTGGTCAAATAAAAAAGCAAGGGCTTTTCTGAACAGATGTTCGGAAAAGCCCCTTTTTTGTTCGCTTAGAGGATGAATGG
CAGCGAAATTGTGTGTTCCA

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MNLFRKKPIQALLNESGAKGASLRKELSAFDLTMLGIGAIIGTGIFVLTGVAAAEHAGPALVLSFALSALACVFAALCYA
EFASTVPVSGSAYTYSYAAFGELIAWILGWDLILEYGVASSAVAAGWSGYFQGLLAGFGIELPKALTSAYDPEKGTIIDL
PAIFIVLFITILLNMGAKKSARFNAIIVFVKVAVILLFLAVGVWYVKPENWTPFMPYGFAGVATGAATVFFAYIGFDAVS
TAAEEVRNPQRNMPIGIIVSLLVCTLLYIAVSLVLTGIVPYDQLNVKNPVAFALSYIQQDWVAGFISLGAIAGITTVLLV
MLYGQTRLFYAISRDGLLPKVFARISPTRQIPYVNTWLTGAAVSVFAGVIPLNKLAELTNIGTLFAFITVSIGVLVLRKT
QPDLKRAFRVPFVPFVPILAVLFCGYLVLQLPATTWIGFVSWLLIGLVIYFAYGRKHSVLNETAESEEKVG

Sequences:

>Translated_471_residues
MNLFRKKPIQALLNESGAKGASLRKELSAFDLTMLGIGAIIGTGIFVLTGVAAAEHAGPALVLSFALSALACVFAALCYA
EFASTVPVSGSAYTYSYAAFGELIAWILGWDLILEYGVASSAVAAGWSGYFQGLLAGFGIELPKALTSAYDPEKGTIIDL
PAIFIVLFITILLNMGAKKSARFNAIIVFVKVAVILLFLAVGVWYVKPENWTPFMPYGFAGVATGAATVFFAYIGFDAVS
TAAEEVRNPQRNMPIGIIVSLLVCTLLYIAVSLVLTGIVPYDQLNVKNPVAFALSYIQQDWVAGFISLGAIAGITTVLLV
MLYGQTRLFYAISRDGLLPKVFARISPTRQIPYVNTWLTGAAVSVFAGVIPLNKLAELTNIGTLFAFITVSIGVLVLRKT
QPDLKRAFRVPFVPFVPILAVLFCGYLVLQLPATTWIGFVSWLLIGLVIYFAYGRKHSVLNETAESEEKVG
>Mature_471_residues
MNLFRKKPIQALLNESGAKGASLRKELSAFDLTMLGIGAIIGTGIFVLTGVAAAEHAGPALVLSFALSALACVFAALCYA
EFASTVPVSGSAYTYSYAAFGELIAWILGWDLILEYGVASSAVAAGWSGYFQGLLAGFGIELPKALTSAYDPEKGTIIDL
PAIFIVLFITILLNMGAKKSARFNAIIVFVKVAVILLFLAVGVWYVKPENWTPFMPYGFAGVATGAATVFFAYIGFDAVS
TAAEEVRNPQRNMPIGIIVSLLVCTLLYIAVSLVLTGIVPYDQLNVKNPVAFALSYIQQDWVAGFISLGAIAGITTVLLV
MLYGQTRLFYAISRDGLLPKVFARISPTRQIPYVNTWLTGAAVSVFAGVIPLNKLAELTNIGTLFAFITVSIGVLVLRKT
QPDLKRAFRVPFVPFVPILAVLFCGYLVLQLPATTWIGFVSWLLIGLVIYFAYGRKHSVLNETAESEEKVG

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=435, Percent_Identity=36.0919540229885, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI258614003, Length=434, Percent_Identity=36.6359447004608, Blast_Score=252, Evalue=6e-67,
Organism=Homo sapiens, GI258614005, Length=434, Percent_Identity=36.6359447004608, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI258645169, Length=418, Percent_Identity=37.5598086124402, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI181337167, Length=413, Percent_Identity=35.8353510895884, Blast_Score=245, Evalue=7e-65,
Organism=Homo sapiens, GI114326544, Length=429, Percent_Identity=35.8974358974359, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI114326550, Length=429, Percent_Identity=35.8974358974359, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI110347453, Length=402, Percent_Identity=36.81592039801, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI187423910, Length=476, Percent_Identity=25.4201680672269, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI7657591, Length=476, Percent_Identity=25.4201680672269, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI186910308, Length=427, Percent_Identity=26.6978922716628, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI186910306, Length=427, Percent_Identity=26.6978922716628, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI186910304, Length=427, Percent_Identity=26.6978922716628, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI115648063, Length=433, Percent_Identity=24.7113163972286, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI115648022, Length=433, Percent_Identity=24.7113163972286, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI33286428, Length=465, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7657683, Length=387, Percent_Identity=26.6149870801034, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI71979932, Length=235, Percent_Identity=27.2340425531915, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87081869, Length=455, Percent_Identity=26.5934065934066, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788480, Length=439, Percent_Identity=26.879271070615, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87082250, Length=418, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081708, Length=452, Percent_Identity=22.3451327433628, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082023, Length=467, Percent_Identity=27.4089935760171, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786302, Length=420, Percent_Identity=22.1428571428571, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786694, Length=264, Percent_Identity=27.6515151515151, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789017, Length=394, Percent_Identity=24.3654822335025, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1786789, Length=432, Percent_Identity=21.7592592592593, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367353, Length=328, Percent_Identity=26.219512195122, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786908, Length=328, Percent_Identity=23.1707317073171, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790653, Length=437, Percent_Identity=20.3661327231121, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081915, Length=422, Percent_Identity=22.5118483412322, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786602, Length=476, Percent_Identity=21.218487394958, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17532491, Length=440, Percent_Identity=34.0909090909091, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17531343, Length=417, Percent_Identity=36.6906474820144, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17533459, Length=419, Percent_Identity=33.6515513126492, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17540018, Length=427, Percent_Identity=26.9320843091335, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17568033, Length=438, Percent_Identity=27.6255707762557, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71982612, Length=418, Percent_Identity=22.7272727272727, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71982608, Length=418, Percent_Identity=22.7272727272727, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=369, Percent_Identity=24.1192411924119, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=348, Percent_Identity=24.4252873563218, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=367, Percent_Identity=23.9782016348774, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537453, Length=330, Percent_Identity=24.8484848484848, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995382, Length=356, Percent_Identity=25.2808988764045, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71995388, Length=356, Percent_Identity=25.2808988764045, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71993915, Length=351, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24667468, Length=401, Percent_Identity=39.1521197007481, Blast_Score=294, Evalue=8e-80,
Organism=Drosophila melanogaster, GI24666159, Length=426, Percent_Identity=37.0892018779343, Blast_Score=272, Evalue=5e-73,
Organism=Drosophila melanogaster, GI221512776, Length=426, Percent_Identity=37.0892018779343, Blast_Score=272, Evalue=5e-73,
Organism=Drosophila melanogaster, GI24668806, Length=402, Percent_Identity=36.318407960199, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI21356285, Length=402, Percent_Identity=36.318407960199, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24668802, Length=402, Percent_Identity=36.318407960199, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI161077963, Length=406, Percent_Identity=37.9310344827586, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI281366235, Length=416, Percent_Identity=33.6538461538462, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI116007820, Length=416, Percent_Identity=33.6538461538462, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI116007818, Length=418, Percent_Identity=33.4928229665072, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI85725152, Length=418, Percent_Identity=33.4928229665072, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21357367, Length=437, Percent_Identity=25.858123569794, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221331183, Length=471, Percent_Identity=24.416135881104, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17647653, Length=471, Percent_Identity=24.416135881104, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24664379, Length=471, Percent_Identity=24.416135881104, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24651635, Length=418, Percent_Identity=25.5980861244019, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24651633, Length=418, Percent_Identity=25.5980861244019, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45550968, Length=465, Percent_Identity=24.3010752688172, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19921172, Length=465, Percent_Identity=24.3010752688172, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24641993, Length=429, Percent_Identity=23.5431235431235, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641995, Length=429, Percent_Identity=23.5431235431235, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50593; Mature: 50593

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]