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The map label for this gene is pabA [H]

Identifier: 138893746

GI number: 138893746

Start: 80120

End: 80698

Strand: Direct

Name: pabA [H]

Synonym: GTNG_0067

Alternate gene names: 138893746

Gene position: 80120-80698 (Clockwise)

Preceding gene: 138893745

Following gene: 138893747

Centisome position: 2.26

GC content: 48.19

Gene sequence:

>579_bases
ATGATGATCGTCATGATTGATAATTATGATTCCTTTACGTACAATTTAGTGCAATATTTAGGTGTTCTAGGTGAGGAGCT
GCTTGTCAAGCGCAATGATGAAATTACCGTTTCCGAGATTGAACGGCTTGCCCCGGATTTTATTATGATTTCCCCAGGTC
CATGCACGCCGAATGAAGCGGGTGTCAGCTTGGAAGCCATCACTTACTTTGCTGGCAAAATCCCGATTTTTGGCGTCTGC
CTCGGCCATCAGTCGATCGCCCAAGCGTTTGGCGGCCGTGTCATCCGTGCTTCAAGGTTGATGCACGGGAAAACATCGTC
CGTTTACCATGACGGAGAAACGATTTTCCAAGGGGTGCCGAGCCCGTTTACGGCGACTCGTTACCACTCTCTCATTGTTG
ACAAAGAAACACTTCCCGATTGTTTTACTGTTTCCGCTTGGACGGACGAAGACGAAGTGATGGCCATCCGCCATAAGACA
TTGCCGATCGAAGGGGTGCAGTTCCACCCCGAGTCGATTATGACAAGTCACGGAATGCAACTGCTGAAAAACTTTATTGA
CACATACAAAAAGGCGTGA

Upstream 100 bases:

>100_bases
CGGAGCATGAATACAAAGAATGTTTGAAAAAAGCGGCGGCCCTTTGGAGAGCAAAAGAGCTGAGTGAAGCAGAGACATTA
TTTTCGAGCATGAGGTGAGA

Downstream 100 bases:

>100_bases
TGGACCATATGTACGTATATGTCAACGGCAAAATCGTTCCGCGTGAAGAAGCGCAACTCTCGGCATTTGATCACGGTTTT
TTGTATGGGCTTGGATTGTT

Product: para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MMIVMIDNYDSFTYNLVQYLGVLGEELLVKRNDEITVSEIERLAPDFIMISPGPCTPNEAGVSLEAITYFAGKIPIFGVC
LGHQSIAQAFGGRVIRASRLMHGKTSSVYHDGETIFQGVPSPFTATRYHSLIVDKETLPDCFTVSAWTDEDEVMAIRHKT
LPIEGVQFHPESIMTSHGMQLLKNFIDTYKKA

Sequences:

>Translated_192_residues
MMIVMIDNYDSFTYNLVQYLGVLGEELLVKRNDEITVSEIERLAPDFIMISPGPCTPNEAGVSLEAITYFAGKIPIFGVC
LGHQSIAQAFGGRVIRASRLMHGKTSSVYHDGETIFQGVPSPFTATRYHSLIVDKETLPDCFTVSAWTDEDEVMAIRHKT
LPIEGVQFHPESIMTSHGMQLLKNFIDTYKKA
>Mature_192_residues
MMIVMIDNYDSFTYNLVQYLGVLGEELLVKRNDEITVSEIERLAPDFIMISPGPCTPNEAGVSLEAITYFAGKIPIFGVC
LGHQSIAQAFGGRVIRASRLMHGKTSSVYHDGETIFQGVPSPFTATRYHSLIVDKETLPDCFTVSAWTDEDEVMAIRHKT
LPIEGVQFHPESIMTSHGMQLLKNFIDTYKKA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=58.9189189189189, Blast_Score=258, Evalue=2e-70,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=43.8502673796791, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI1788854, Length=159, Percent_Identity=28.3018867924528, Blast_Score=64, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=186, Percent_Identity=48.3870967741936, Blast_Score=194, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=30.6603773584906, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323873, Length=142, Percent_Identity=30.9859154929577, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 21420; Mature: 21420

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIVMIDNYDSFTYNLVQYLGVLGEELLVKRNDEITVSEIERLAPDFIMISPGPCTPNEA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCCCCCCCC
GVSLEAITYFAGKIPIFGVCLGHQSIAQAFGGRVIRASRLMHGKTSSVYHDGETIFQGVP
CCCHHHHHHHHCCCCEEEEEECHHHHHHHHCCEEEEHHHHHCCCCCCEEECCHHHHCCCC
SPFTATRYHSLIVDKETLPDCFTVSAWTDEDEVMAIRHKTLPIEGVQFHPESIMTSHGMQ
CCCCHHHHHHEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHH
LLKNFIDTYKKA
HHHHHHHHHHCC
>Mature Secondary Structure
MMIVMIDNYDSFTYNLVQYLGVLGEELLVKRNDEITVSEIERLAPDFIMISPGPCTPNEA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCCCCCCCC
GVSLEAITYFAGKIPIFGVCLGHQSIAQAFGGRVIRASRLMHGKTSSVYHDGETIFQGVP
CCCHHHHHHHHCCCCEEEEEECHHHHHHHHCCEEEEHHHHHCCCCCCEEECCHHHHCCCC
SPFTATRYHSLIVDKETLPDCFTVSAWTDEDEVMAIRHKTLPIEGVQFHPESIMTSHGMQ
CCCCHHHHHHEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHH
LLKNFIDTYKKA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]