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The map label for this gene is pabB [H]

Identifier: 138893745

GI number: 138893745

Start: 78696

End: 80117

Strand: Direct

Name: pabB [H]

Synonym: GTNG_0066

Alternate gene names: 138893745

Gene position: 78696-80117 (Clockwise)

Preceding gene: 138893744

Following gene: 138893746

Centisome position: 2.22

GC content: 53.09

Gene sequence:

>1422_bases
ATGGAACAACGGCGCAGGCGGCTGAAACGGACAATCGATTATAGCGGCCGGGATTGGTTCCGCCAGTACGAACAGCTGGC
ATACGGTCGACCGCACCACGTGCTGCTTGAGAGCGGTCAAGGGGGAAGATATAGCATCATCGGCCTCAACCCAAGCGGGA
TCATCCGGGCGACTGAGCAGCGGTTATCTATCATCTATCGTGGGAAAGAAACGACGCTGGACGGGCCACCGCTCGAGTTG
CTGCAACAATGGTTTTCGCACTTTTTAATGCCGGATGAGGACGAGCCACTGCCGTGTCAAGGTGGACTGATCGGCTACAT
CAGCTATGACAGCGTCCGTTACATCGAACGGCTTCCGGAGCTTGCTCATGACGATTTGCAGCTGCCGTTTATGTATTTTT
GGCTGTTTGATGATGTGGCGATTTACGACCATCAAGAACAGCAGCTCCACTTGATCGTCCATGCCAGCGATGGGGAGGAA
CAGGCTGCTTTTCGAAGATTGGATATGTATGAGCAAATGTGGCTTGAGGAGCAGAGTGAATCACCCCGATGGTCAACTGC
TGGCTCGGCCGCCGCTCCGTCTGTGTCCATGACGAAACAGCAGTTTATCGAGGCGGTTCAGCGCGTGAAGCAGTACATTG
CCCAAGGTGACGTGTTCCAAGTCAACTTGTCGGTGCGCCAATCACAGCCGCTCTTAGCTCATCCATTTGCCGTCTACAAG
CAGTTGCGTACCATTAATCCGTCGCCGTATATGGGGTATTTGCATACCCCACAATTTCAAGTTGTGAGCGGTTCGCCAGA
GTTGCTTGTCCGTAAACGTGGACAGCGTCTCGAAACACGGCCGATTGCCGGTACCCGGTCACGTGGCCGGACGAAAACGG
AAGATGAACAAATTGCACAAAAATTGCTCGCGAGCGAAAAGGAGCGAGCCGAGCATGCCATGCTCGTCGATCTTGAACGA
AACGATCTCGGCCGCGTCTGTGCATATGGGACGGTTCATGTCGACGAATGGATGACAGTCGAACGATATTCGCACGTCAT
GCATATTGTGTCGCATGTTTCCGGAACAATCGCGCCAGAATACGATGCGTTTGCCGTCATTCGCGCCATGTTTCCAGGAG
GGACGATTACGGGGGCCCCGAAAGTGCGGACGATGGAAATTATCGAAGAACTCGAACCGGTCCGCCGCGGCTTGTATACC
GGGTCGATCGGCTGGATCGATTTTCAAGGCAACATGGAGCTGAACATCGCCATTCGGACGATGGTTGTCAAAGATGGAAT
AGCGCATGTACAAGCAGGGGCAGGTATTGTCATTGATTCCAACCCGGAGCATGAATACAAAGAATGTTTGAAAAAAGCGG
CGGCCCTTTGGAGAGCAAAAGAGCTGAGTGAAGCAGAGACATTATTTTCGAGCATGAGGTGA

Upstream 100 bases:

>100_bases
CAGGGGCAACCCTGTCGAATTTTTTATGGTAGTGGGTGATATGAATGACTAATCATTGTACAATAAGAATAACTATGAAC
ATCATGAGGAGTTGACCGAG

Downstream 100 bases:

>100_bases
GAATGATGATCGTCATGATTGATAATTATGATTCCTTTACGTACAATTTAGTGCAATATTTAGGTGTTCTAGGTGAGGAG
CTGCTTGTCAAGCGCAATGA

Product: P-aminobenzoate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MEQRRRRLKRTIDYSGRDWFRQYEQLAYGRPHHVLLESGQGGRYSIIGLNPSGIIRATEQRLSIIYRGKETTLDGPPLEL
LQQWFSHFLMPDEDEPLPCQGGLIGYISYDSVRYIERLPELAHDDLQLPFMYFWLFDDVAIYDHQEQQLHLIVHASDGEE
QAAFRRLDMYEQMWLEEQSESPRWSTAGSAAAPSVSMTKQQFIEAVQRVKQYIAQGDVFQVNLSVRQSQPLLAHPFAVYK
QLRTINPSPYMGYLHTPQFQVVSGSPELLVRKRGQRLETRPIAGTRSRGRTKTEDEQIAQKLLASEKERAEHAMLVDLER
NDLGRVCAYGTVHVDEWMTVERYSHVMHIVSHVSGTIAPEYDAFAVIRAMFPGGTITGAPKVRTMEIIEELEPVRRGLYT
GSIGWIDFQGNMELNIAIRTMVVKDGIAHVQAGAGIVIDSNPEHEYKECLKKAAALWRAKELSEAETLFSSMR

Sequences:

>Translated_473_residues
MEQRRRRLKRTIDYSGRDWFRQYEQLAYGRPHHVLLESGQGGRYSIIGLNPSGIIRATEQRLSIIYRGKETTLDGPPLEL
LQQWFSHFLMPDEDEPLPCQGGLIGYISYDSVRYIERLPELAHDDLQLPFMYFWLFDDVAIYDHQEQQLHLIVHASDGEE
QAAFRRLDMYEQMWLEEQSESPRWSTAGSAAAPSVSMTKQQFIEAVQRVKQYIAQGDVFQVNLSVRQSQPLLAHPFAVYK
QLRTINPSPYMGYLHTPQFQVVSGSPELLVRKRGQRLETRPIAGTRSRGRTKTEDEQIAQKLLASEKERAEHAMLVDLER
NDLGRVCAYGTVHVDEWMTVERYSHVMHIVSHVSGTIAPEYDAFAVIRAMFPGGTITGAPKVRTMEIIEELEPVRRGLYT
GSIGWIDFQGNMELNIAIRTMVVKDGIAHVQAGAGIVIDSNPEHEYKECLKKAAALWRAKELSEAETLFSSMR
>Mature_473_residues
MEQRRRRLKRTIDYSGRDWFRQYEQLAYGRPHHVLLESGQGGRYSIIGLNPSGIIRATEQRLSIIYRGKETTLDGPPLEL
LQQWFSHFLMPDEDEPLPCQGGLIGYISYDSVRYIERLPELAHDDLQLPFMYFWLFDDVAIYDHQEQQLHLIVHASDGEE
QAAFRRLDMYEQMWLEEQSESPRWSTAGSAAAPSVSMTKQQFIEAVQRVKQYIAQGDVFQVNLSVRQSQPLLAHPFAVYK
QLRTINPSPYMGYLHTPQFQVVSGSPELLVRKRGQRLETRPIAGTRSRGRTKTEDEQIAQKLLASEKERAEHAMLVDLER
NDLGRVCAYGTVHVDEWMTVERYSHVMHIVSHVSGTIAPEYDAFAVIRAMFPGGTITGAPKVRTMEIIEELEPVRRGLYT
GSIGWIDFQGNMELNIAIRTMVVKDGIAHVQAGAGIVIDSNPEHEYKECLKKAAALWRAKELSEAETLFSSMR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=452, Percent_Identity=36.283185840708, Blast_Score=269, Evalue=4e-73,
Organism=Escherichia coli, GI1787518, Length=366, Percent_Identity=37.1584699453552, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786809, Length=209, Percent_Identity=30.1435406698565, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082077, Length=263, Percent_Identity=25.4752851711027, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320935, Length=455, Percent_Identity=39.5604395604396, Blast_Score=297, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6324361, Length=394, Percent_Identity=23.3502538071066, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 54138; Mature: 54138

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRRRRLKRTIDYSGRDWFRQYEQLAYGRPHHVLLESGQGGRYSIIGLNPSGIIRATEQ
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCEEEHHH
RLSIIYRGKETTLDGPPLELLQQWFSHFLMPDEDEPLPCQGGLIGYISYDSVRYIERLPE
HEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHH
LAHDDLQLPFMYFWLFDDVAIYDHQEQQLHLIVHASDGEEQAAFRRLDMYEQMWLEEQSE
HHCCCCCCHHHEEHHHHCHHEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
SPRWSTAGSAAAPSVSMTKQQFIEAVQRVKQYIAQGDVFQVNLSVRQSQPLLAHPFAVYK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHH
QLRTINPSPYMGYLHTPQFQVVSGSPELLVRKRGQRLETRPIAGTRSRGRTKTEDEQIAQ
HHHCCCCCCCCCEEECCCEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
KLLASEKERAEHAMLVDLERNDLGRVCAYGTVHVDEWMTVERYSHVMHIVSHVSGTIAPE
HHHHHHHHHCCCEEEEEECCCCCCCCCEECEEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
YDAFAVIRAMFPGGTITGAPKVRTMEIIEELEPVRRGLYTGSIGWIDFQGNMELNIAIRT
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEEEE
MVVKDGIAHVQAGAGIVIDSNPEHEYKECLKKAAALWRAKELSEAETLFSSMR
EEECCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQRRRRLKRTIDYSGRDWFRQYEQLAYGRPHHVLLESGQGGRYSIIGLNPSGIIRATEQ
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCEEEHHH
RLSIIYRGKETTLDGPPLELLQQWFSHFLMPDEDEPLPCQGGLIGYISYDSVRYIERLPE
HEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHH
LAHDDLQLPFMYFWLFDDVAIYDHQEQQLHLIVHASDGEEQAAFRRLDMYEQMWLEEQSE
HHCCCCCCHHHEEHHHHCHHEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
SPRWSTAGSAAAPSVSMTKQQFIEAVQRVKQYIAQGDVFQVNLSVRQSQPLLAHPFAVYK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHH
QLRTINPSPYMGYLHTPQFQVVSGSPELLVRKRGQRLETRPIAGTRSRGRTKTEDEQIAQ
HHHCCCCCCCCCEEECCCEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
KLLASEKERAEHAMLVDLERNDLGRVCAYGTVHVDEWMTVERYSHVMHIVSHVSGTIAPE
HHHHHHHHHCCCEEEEEECCCCCCCCCEECEEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
YDAFAVIRAMFPGGTITGAPKVRTMEIIEELEPVRRGLYTGSIGWIDFQGNMELNIAIRT
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEEEE
MVVKDGIAHVQAGAGIVIDSNPEHEYKECLKKAAALWRAKELSEAETLFSSMR
EEECCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]