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The map label for this gene is yabD [H]

Identifier: 138893710

GI number: 138893710

Start: 44179

End: 44949

Strand: Direct

Name: yabD [H]

Synonym: GTNG_0031

Alternate gene names: 138893710

Gene position: 44179-44949 (Clockwise)

Preceding gene: 138893709

Following gene: 138893711

Centisome position: 1.24

GC content: 46.17

Gene sequence:

>771_bases
ATGCTTTTTGATACGCACGCGCATTTGAATGCGGTCCAATATGAAGAAGATTTAGAACAAGTCATTGAGCGCGCCCGTGC
TGAAGGGGTTTCGTATATTGTTGTTGTCGGATTTGACCGCCTGACGATTGACCGGGCGATTGAGCTGGCTGAGCGGTATC
CATTTATTTACGCAGCGGTTGGCTGGCATCCGGTCGATGCGATTGACATGACCGATGACGACCTACAGATGATTGAGCAG
CTCGCCTCCCATCCGAAAGTGGTGGCACTTGGCGAGATGGGGCTTGATTACCATTGGGATAAATCACCAAAAGATGTCCA
ACAAGATGTATTTCGCCGGCAAATTGCCCTAGCAAAAAAAGTAAAGCTTCCAATCATCATTCATAATCGTGAGGCAACGG
CGGATATTTTAAAAATTTTACAAGAAGAAAACGCCGCCGAAGTAGGCGGCATTATGCATTGTTTTAGTGGTAGTGTCGAA
GTAGCGAGACAATGTATCGAAATGAATTTTCTCATTTCCCTTGGTGGTCCGGTCACGTTTAAAAATGCGAAAAAGCCGAA
GGAAGTGGCAAAGGAAATTCCGCTCAGCCATTTATTGATTGAGACTGATTGTCCGTATCTAACGCCTCACCCTTTCCGCG
GAAAACGAAACGAGCCGAGCTATGTCAAATATGTTGCCGAGGCGATCGCGGAGATTAAAAACGTTTCTTTTGACGAAGTG
GCGAAAACAACGATGGAAAATGCCAAAAGATTGTTCGCCATCGACCGCTAA

Upstream 100 bases:

>100_bases
TCCTTGTCGTTATTTTGTAATGTAAATGTTAATGAACTGTGATATACGTAATCAATTTCTATGCTACACTTATCAACAAG
GTGGAAAAGAGGGTAGTTGT

Downstream 100 bases:

>100_bases
AATTAGGCATCAAATGATGGGGAGGCTTGTCGAAAGAACAGAGGAGACGAAAAAGTTCTACAAATTTAGCCAATATGGGC
CAATCAGATATCGACAAGTC

Product: TatD family deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLFDTHAHLNAVQYEEDLEQVIERARAEGVSYIVVVGFDRLTIDRAIELAERYPFIYAAVGWHPVDAIDMTDDDLQMIEQ
LASHPKVVALGEMGLDYHWDKSPKDVQQDVFRRQIALAKKVKLPIIIHNREATADILKILQEENAAEVGGIMHCFSGSVE
VARQCIEMNFLISLGGPVTFKNAKKPKEVAKEIPLSHLLIETDCPYLTPHPFRGKRNEPSYVKYVAEAIAEIKNVSFDEV
AKTTMENAKRLFAIDR

Sequences:

>Translated_256_residues
MLFDTHAHLNAVQYEEDLEQVIERARAEGVSYIVVVGFDRLTIDRAIELAERYPFIYAAVGWHPVDAIDMTDDDLQMIEQ
LASHPKVVALGEMGLDYHWDKSPKDVQQDVFRRQIALAKKVKLPIIIHNREATADILKILQEENAAEVGGIMHCFSGSVE
VARQCIEMNFLISLGGPVTFKNAKKPKEVAKEIPLSHLLIETDCPYLTPHPFRGKRNEPSYVKYVAEAIAEIKNVSFDEV
AKTTMENAKRLFAIDR
>Mature_256_residues
MLFDTHAHLNAVQYEEDLEQVIERARAEGVSYIVVVGFDRLTIDRAIELAERYPFIYAAVGWHPVDAIDMTDDDLQMIEQ
LASHPKVVALGEMGLDYHWDKSPKDVQQDVFRRQIALAKKVKLPIIIHNREATADILKILQEENAAEVGGIMHCFSGSVE
VARQCIEMNFLISLGGPVTFKNAKKPKEVAKEIPLSHLLIETDCPYLTPHPFRGKRNEPSYVKYVAEAIAEIKNVSFDEV
AKTTMENAKRLFAIDR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=32.3308270676692, Blast_Score=130, Evalue=9e-31,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=32.3308270676692, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=31.9852941176471, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI226061614, Length=253, Percent_Identity=31.6205533596838, Blast_Score=124, Evalue=6e-29,
Organism=Homo sapiens, GI14042943, Length=269, Percent_Identity=29.7397769516729, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI225903424, Length=206, Percent_Identity=30.5825242718447, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI225903439, Length=236, Percent_Identity=30.0847457627119, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=30.5676855895196, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=37.984496124031, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=33.7254901960784, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=30.5019305019305, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=35.2313167259786, Blast_Score=170, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=29.5019157088123, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17543026, Length=185, Percent_Identity=34.5945945945946, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=234, Percent_Identity=34.6153846153846, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=31.9298245614035, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI221330018, Length=277, Percent_Identity=29.2418772563177, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24586117, Length=277, Percent_Identity=29.2418772563177, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 28987; Mature: 28987

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDTHAHLNAVQYEEDLEQVIERARAEGVSYIVVVGFDRLTIDRAIELAERYPFIYAAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCEEEEEC
GWHPVDAIDMTDDDLQMIEQLASHPKVVALGEMGLDYHWDKSPKDVQQDVFRRQIALAKK
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VKLPIIIHNREATADILKILQEENAAEVGGIMHCFSGSVEVARQCIEMNFLISLGGPVTF
CCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCEEE
KNAKKPKEVAKEIPLSHLLIETDCPYLTPHPFRGKRNEPSYVKYVAEAIAEIKNVSFDEV
CCCCCHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
AKTTMENAKRLFAIDR
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLFDTHAHLNAVQYEEDLEQVIERARAEGVSYIVVVGFDRLTIDRAIELAERYPFIYAAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCEEEEEC
GWHPVDAIDMTDDDLQMIEQLASHPKVVALGEMGLDYHWDKSPKDVQQDVFRRQIALAKK
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VKLPIIIHNREATADILKILQEENAAEVGGIMHCFSGSVEVARQCIEMNFLISLGGPVTF
CCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCEEE
KNAKKPKEVAKEIPLSHLLIETDCPYLTPHPFRGKRNEPSYVKYVAEAIAEIKNVSFDEV
CCCCCHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
AKTTMENAKRLFAIDR
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]