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The map label for this gene is rnr [C]

Identifier: 134302635

GI number: 134302635

Start: 1707052

End: 1708908

Strand: Direct

Name: rnr [C]

Synonym: FTW_1816

Alternate gene names: 134302635

Gene position: 1707052-1708908 (Clockwise)

Preceding gene: 134302632

Following gene: 134302636

Centisome position: 89.92

GC content: 33.06

Gene sequence:

>1857_bases
ATGCAAAAAAATTCTCTAGTAATATTTAAATCTAAACCAGCAAAGGTTATTAATCTCTTAGATAAAAAAATTGAGATTGA
GACTCTCGATGGTAAAAATATTAAGTTACCCGCAAAGAGTGTTCAATTACTTGTAGAGTCAGAAAAGGATTTTGAACTTG
AAAGTTTAAAAGAGCTAGAAATAGCTGAACTTGAAATGACTTGGGAATTATTACAAGAGCAACAACAAACATCTGTTGAA
GAGCTATGTGAGTTACTTTTTGAATCTATAGGGGTAAATCAGGCTTATACCGTGTGGCTTTTAGTTTCAGAAGGAGAGTA
TTTTAGCTTTAATGATGATTTTAGTATCAATATTCATTCACAAGAGCAAAAAAATGCAATAGTTAGAGACAAACAAGAGA
AACTTAAAAAAGAGCAAGAACTTAATGATTTCATAGAGCGTTTAAACAATAAGACTTTTAATGAAGATGATAGGAAATTT
CTTAAGGAAATAGAAGCTCTAGCAACACTTAAAACTAATAAGTGTCGTTTTTTTAAGTACTTAAACATGGAGGAGTCTGA
GAATAGTGCGTATAAATTGCTTTTGGATATTGGCTATTGTGATGAGTTTTTTAACCCTTATTTATACAGGTATGGTGCTG
AGTTAGAACATAATTCTGCAGAGTTTAACTACAATTCTAAATCAGATAACCAGCGAGTAGATCTGACACATTTAAAGGCT
TATGCTATAGATGATGAAGGTAGTAATGATCCTGATGATGCAATTAGTTGGGATAGCCAAAAAAATAAAATGTGGGTACA
TATCGCAGATCCTTCTTCTAGTATTAGTTTTGGTGATGAGGTTGATCTTCAAGCTAGAGCACGAGGCTCAAATTTATATG
TGCCGGAACAGATAGTCATGATGTTACCTCCTCAAGCAACAGCAAAATTAGGCTTAGGCTTACAGGAGGTATCTCCTGCA
GTATCTGTAGGATTTAGGATTGATGAGCAAGGTGATATCCATGATATTGAAATATGCTTTAGTAATATAAAAGTTACACG
ATATTCTTATGAATTTGTTGAAGAAAATATGCATACTTTAGAGCTTGGCGATATAGTAAGTTATGCAAAATATTTCACTG
ATAAGCGTTTATCTAAAGGTGCAGTTGAGCTTGATTTCCCAGAGATAAAGATATCATTAGATGCTAATAAAAATGTTAAA
TTAACTGATTTACCACGTTTAAACTCAAGGACACTTGTACGAGATACAATGCTAATGGCTGGTGTTGCAGTAGGACAGTT
TTGTATTAAAAATAATATTAGTGTATCCTTTTCTACACAGCCTGAACATGATCTTGGACAAGATGGTTTAGAGAATATCG
ATTCAATAGCTGATATGTTTGCAACACGCAAAAAACTCCAAAGAGGCAGATATTCTACACAACCTAGTATGCATGCAGGG
ATGGGATTAGAAGCCTATGTACAAGTAACTAGTCCATTGAGAAGATACCTTGATTTGATTGTACACTATCAGTTACGTAA
TTTTCTGCAGCATAAAGAGATGATAAGTGCTCAAGAGATTGATAACATAATTGCTCAAGTTGATATTCCTATAAAATCAA
ATAGACAAACTGAGCGTTTCTCAAATTCACACTGGAAGTTGGTTTACCTAATCCAAAATCCTGACCTGGAATTTCAAGCG
ACAGTTATTGAGAAATTAGAAAAAAGTAGATTAATGGTTTCTATTGCAGCTTTAGCGATGACTAAAAAACTTTCTGTCAG
CGGTAAGTATGATTTAAATGATCAAATAAAGTTACAAAACACCTCAGTAAACCTTGTTACACAAGAGGCTTTCTTTAGAG
TTATTGAAGAAAATTAA

Upstream 100 bases:

>100_bases
ACTATTTTATAGATAGCAAGTCATAGAACTTAAGACTAAACTTTTACTTCATCTAGCAATTGAGTAGAATATCTATAATT
AATAAGAATGATACAGAAAA

Downstream 100 bases:

>100_bases
CCATATTCTAACAATAAATTAACAGTTTTATCCACAGGGCGTGAAAAATATTTATAAACAATATATTTCTCGATATCTAG
ATGCTCAAAGTATTGTAAAT

Product: ribonuclease II family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MQKNSLVIFKSKPAKVINLLDKKIEIETLDGKNIKLPAKSVQLLVESEKDFELESLKELEIAELEMTWELLQEQQQTSVE
ELCELLFESIGVNQAYTVWLLVSEGEYFSFNDDFSINIHSQEQKNAIVRDKQEKLKKEQELNDFIERLNNKTFNEDDRKF
LKEIEALATLKTNKCRFFKYLNMEESENSAYKLLLDIGYCDEFFNPYLYRYGAELEHNSAEFNYNSKSDNQRVDLTHLKA
YAIDDEGSNDPDDAISWDSQKNKMWVHIADPSSSISFGDEVDLQARARGSNLYVPEQIVMMLPPQATAKLGLGLQEVSPA
VSVGFRIDEQGDIHDIEICFSNIKVTRYSYEFVEENMHTLELGDIVSYAKYFTDKRLSKGAVELDFPEIKISLDANKNVK
LTDLPRLNSRTLVRDTMLMAGVAVGQFCIKNNISVSFSTQPEHDLGQDGLENIDSIADMFATRKKLQRGRYSTQPSMHAG
MGLEAYVQVTSPLRRYLDLIVHYQLRNFLQHKEMISAQEIDNIIAQVDIPIKSNRQTERFSNSHWKLVYLIQNPDLEFQA
TVIEKLEKSRLMVSIAALAMTKKLSVSGKYDLNDQIKLQNTSVNLVTQEAFFRVIEEN

Sequences:

>Translated_618_residues
MQKNSLVIFKSKPAKVINLLDKKIEIETLDGKNIKLPAKSVQLLVESEKDFELESLKELEIAELEMTWELLQEQQQTSVE
ELCELLFESIGVNQAYTVWLLVSEGEYFSFNDDFSINIHSQEQKNAIVRDKQEKLKKEQELNDFIERLNNKTFNEDDRKF
LKEIEALATLKTNKCRFFKYLNMEESENSAYKLLLDIGYCDEFFNPYLYRYGAELEHNSAEFNYNSKSDNQRVDLTHLKA
YAIDDEGSNDPDDAISWDSQKNKMWVHIADPSSSISFGDEVDLQARARGSNLYVPEQIVMMLPPQATAKLGLGLQEVSPA
VSVGFRIDEQGDIHDIEICFSNIKVTRYSYEFVEENMHTLELGDIVSYAKYFTDKRLSKGAVELDFPEIKISLDANKNVK
LTDLPRLNSRTLVRDTMLMAGVAVGQFCIKNNISVSFSTQPEHDLGQDGLENIDSIADMFATRKKLQRGRYSTQPSMHAG
MGLEAYVQVTSPLRRYLDLIVHYQLRNFLQHKEMISAQEIDNIIAQVDIPIKSNRQTERFSNSHWKLVYLIQNPDLEFQA
TVIEKLEKSRLMVSIAALAMTKKLSVSGKYDLNDQIKLQNTSVNLVTQEAFFRVIEEN
>Mature_618_residues
MQKNSLVIFKSKPAKVINLLDKKIEIETLDGKNIKLPAKSVQLLVESEKDFELESLKELEIAELEMTWELLQEQQQTSVE
ELCELLFESIGVNQAYTVWLLVSEGEYFSFNDDFSINIHSQEQKNAIVRDKQEKLKKEQELNDFIERLNNKTFNEDDRKF
LKEIEALATLKTNKCRFFKYLNMEESENSAYKLLLDIGYCDEFFNPYLYRYGAELEHNSAEFNYNSKSDNQRVDLTHLKA
YAIDDEGSNDPDDAISWDSQKNKMWVHIADPSSSISFGDEVDLQARARGSNLYVPEQIVMMLPPQATAKLGLGLQEVSPA
VSVGFRIDEQGDIHDIEICFSNIKVTRYSYEFVEENMHTLELGDIVSYAKYFTDKRLSKGAVELDFPEIKISLDANKNVK
LTDLPRLNSRTLVRDTMLMAGVAVGQFCIKNNISVSFSTQPEHDLGQDGLENIDSIADMFATRKKLQRGRYSTQPSMHAG
MGLEAYVQVTSPLRRYLDLIVHYQLRNFLQHKEMISAQEIDNIIAQVDIPIKSNRQTERFSNSHWKLVYLIQNPDLEFQA
TVIEKLEKSRLMVSIAALAMTKKLSVSGKYDLNDQIKLQNTSVNLVTQEAFFRVIEEN

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323943, Length=394, Percent_Identity=25.3807106598985, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324552, Length=346, Percent_Identity=26.0115606936416, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24649634, Length=336, Percent_Identity=24.702380952381, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 71052; Mature: 71052

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKNSLVIFKSKPAKVINLLDKKIEIETLDGKNIKLPAKSVQLLVESEKDFELESLKELE
CCCCCEEEECCCCHHHHHHHHCEEEEEEECCCCEECCHHHHHEEEECCCCCCHHHHHCCH
IAELEMTWELLQEQQQTSVEELCELLFESIGVNQAYTVWLLVSEGEYFSFNDDFSINIHS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEEECCCEEECCCCEEEEEEC
QEQKNAIVRDKQEKLKKEQELNDFIERLNNKTFNEDDRKFLKEIEALATLKTNKCRFFKY
CHHCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
LNMEESENSAYKLLLDIGYCDEFFNPYLYRYGAELEHNSAEFNYNSKSDNQRVDLTHLKA
ECCCCCCCCEEEEEEEECCHHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEE
YAIDDEGSNDPDDAISWDSQKNKMWVHIADPSSSISFGDEVDLQARARGSNLYVPEQIVM
EEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCEEE
MLPPQATAKLGLGLQEVSPAVSVGFRIDEQGDIHDIEICFSNIKVTRYSYEFVEENMHTL
ECCCCHHHHHCCCHHHCCCHHHEEEEECCCCCEEEEEEEEECEEEEEEEHHHHHCCCCEE
ELGDIVSYAKYFTDKRLSKGAVELDFPEIKISLDANKNVKLTDLPRLNSRTLVRDTMLMA
EHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHH
GVAVGQFCIKNNISVSFSTQPEHDLGQDGLENIDSIADMFATRKKLQRGRYSTQPSMHAG
HHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHC
MGLEAYVQVTSPLRRYLDLIVHYQLRNFLQHKEMISAQEIDNIIAQVDIPIKSNRQTERF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHH
SNSHWKLVYLIQNPDLEFQATVIEKLEKSRLMVSIAALAMTKKLSVSGKYDLNDQIKLQN
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEC
TSVNLVTQEAFFRVIEEN
CEEEEEEHHHHHHHHCCC
>Mature Secondary Structure
MQKNSLVIFKSKPAKVINLLDKKIEIETLDGKNIKLPAKSVQLLVESEKDFELESLKELE
CCCCCEEEECCCCHHHHHHHHCEEEEEEECCCCEECCHHHHHEEEECCCCCCHHHHHCCH
IAELEMTWELLQEQQQTSVEELCELLFESIGVNQAYTVWLLVSEGEYFSFNDDFSINIHS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEEECCCEEECCCCEEEEEEC
QEQKNAIVRDKQEKLKKEQELNDFIERLNNKTFNEDDRKFLKEIEALATLKTNKCRFFKY
CHHCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
LNMEESENSAYKLLLDIGYCDEFFNPYLYRYGAELEHNSAEFNYNSKSDNQRVDLTHLKA
ECCCCCCCCEEEEEEEECCHHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEE
YAIDDEGSNDPDDAISWDSQKNKMWVHIADPSSSISFGDEVDLQARARGSNLYVPEQIVM
EEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCEEE
MLPPQATAKLGLGLQEVSPAVSVGFRIDEQGDIHDIEICFSNIKVTRYSYEFVEENMHTL
ECCCCHHHHHCCCHHHCCCHHHEEEEECCCCCEEEEEEEEECEEEEEEEHHHHHCCCCEE
ELGDIVSYAKYFTDKRLSKGAVELDFPEIKISLDANKNVKLTDLPRLNSRTLVRDTMLMA
EHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHH
GVAVGQFCIKNNISVSFSTQPEHDLGQDGLENIDSIADMFATRKKLQRGRYSTQPSMHAG
HHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHC
MGLEAYVQVTSPLRRYLDLIVHYQLRNFLQHKEMISAQEIDNIIAQVDIPIKSNRQTERF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHH
SNSHWKLVYLIQNPDLEFQATVIEKLEKSRLMVSIAALAMTKKLSVSGKYDLNDQIKLQN
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEC
TSVNLVTQEAFFRVIEEN
CEEEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]