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The map label for this gene is mraY [H]

Identifier: 134302472

GI number: 134302472

Start: 1524263

End: 1525360

Strand: Reverse

Name: mraY [H]

Synonym: FTW_1620

Alternate gene names: 134302472

Gene position: 1525360-1524263 (Counterclockwise)

Preceding gene: 134302473

Following gene: 134302471

Centisome position: 80.35

GC content: 33.7

Gene sequence:

>1098_bases
ATGCTGATTTATCTTTTTGAATGGTTAAGTCATTATTTCAAAGGCTTAGAAGTTTTTAGTAATTATATATCTGTTAGAAT
AATTATGATTTCGATAACATCGTTACTCATTACTCTTGCACTAGGTAGACCTATGATCAGCTGGTTACAAAAAATGCAAA
TAGGTCAAATTGTTAGAGATGATGGGCCACAAAGTCATTTCTCTAAAAGAAACACTCCAACAATGGGAGGCGTTTTGATC
CTTTCATCAGTTATTATTTCTTGTTTGCTTTGGGGGGATTTGACAAGTATATATTTATGGATTTTAATTTTAGTGGTTAT
TTTCTTCGGAGCGATTGGTTTTTTTGATGATTATTTGAAGCTAGTACTTAAGCATCCAAAAGGTTTAAGAGCTAAGTATA
AGTTTGCTTTGCAATCAATTTTCTCAATAGTCTTGGCTATAGTTTTATTTTATCTATTGTCTAAGAATGGCCAGATGAGT
TTGTCGATACCATTCTCAAAGAGTCTTTATATTCCAATGGGTATCGTAATATTCGTAGTTTTGGCGTTTTTTATTATTAA
TGGCAGTAGTAATGCTGTCAATCTTACTGATGGGCTAGATGGTTTGGCTATTGTACCTGTAGTACTTGTGGCTGCTGGGT
TAGGTATTTATGCATATATTGAAACTAATAGTACTTTAGCGAATTATTTATTATTTAATTATTTAGGTAATCCTGGACTT
GCTGAGGTGGCGGTATTTTGTGCAGCTGTTTGTGGGTCTGGTTTAGCATTTTTGTGGTTCAATTCCCATCCAGCTGAAGT
ATTTATGGGTGATGTTGGTTCTTTGACATTAGGTGCTGTGTTAGGAGTAATTGCAGTGATGGTACGTCAAGAGTTGATAT
TTTTTATCATGGGGTTGTTATTTGTAGTAGAAGCTCTATCAGTAATGTTACAAGTAGGCTCATATAAGCTTAGAAATGGT
AAGAGAATTTTTAGAATGGCGCCTATTCATCATCATTTTGAATTGAAAGGCTGGCCAGAAACAAAAGTTGTGATACGATT
TTGGATAATTTCTTTGATACTTTTCTTAATTGGTTTGGCAGCTATCAAGGTTAGATAA

Upstream 100 bases:

>100_bases
ATAAAAAATTTGAACCAATTATTTAGACGCTAATTTTGACTCTATTAAAAAAATAACATATCTATTATAATACTCCAAGG
TCATTAAACATTTTAAATAT

Downstream 100 bases:

>100_bases
TGTTTAGTTTTTATTTTAATGATAACAAGATAACCAAACTATTAATGGTTGGTTATGGTTCTACTGGTAAGTCTGTTTGT
GATTTTCTTGCGAACTTTAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MLIYLFEWLSHYFKGLEVFSNYISVRIIMISITSLLITLALGRPMISWLQKMQIGQIVRDDGPQSHFSKRNTPTMGGVLI
LSSVIISCLLWGDLTSIYLWILILVVIFFGAIGFFDDYLKLVLKHPKGLRAKYKFALQSIFSIVLAIVLFYLLSKNGQMS
LSIPFSKSLYIPMGIVIFVVLAFFIINGSSNAVNLTDGLDGLAIVPVVLVAAGLGIYAYIETNSTLANYLLFNYLGNPGL
AEVAVFCAAVCGSGLAFLWFNSHPAEVFMGDVGSLTLGAVLGVIAVMVRQELIFFIMGLLFVVEALSVMLQVGSYKLRNG
KRIFRMAPIHHHFELKGWPETKVVIRFWIISLILFLIGLAAIKVR

Sequences:

>Translated_365_residues
MLIYLFEWLSHYFKGLEVFSNYISVRIIMISITSLLITLALGRPMISWLQKMQIGQIVRDDGPQSHFSKRNTPTMGGVLI
LSSVIISCLLWGDLTSIYLWILILVVIFFGAIGFFDDYLKLVLKHPKGLRAKYKFALQSIFSIVLAIVLFYLLSKNGQMS
LSIPFSKSLYIPMGIVIFVVLAFFIINGSSNAVNLTDGLDGLAIVPVVLVAAGLGIYAYIETNSTLANYLLFNYLGNPGL
AEVAVFCAAVCGSGLAFLWFNSHPAEVFMGDVGSLTLGAVLGVIAVMVRQELIFFIMGLLFVVEALSVMLQVGSYKLRNG
KRIFRMAPIHHHFELKGWPETKVVIRFWIISLILFLIGLAAIKVR
>Mature_365_residues
MLIYLFEWLSHYFKGLEVFSNYISVRIIMISITSLLITLALGRPMISWLQKMQIGQIVRDDGPQSHFSKRNTPTMGGVLI
LSSVIISCLLWGDLTSIYLWILILVVIFFGAIGFFDDYLKLVLKHPKGLRAKYKFALQSIFSIVLAIVLFYLLSKNGQMS
LSIPFSKSLYIPMGIVIFVVLAFFIINGSSNAVNLTDGLDGLAIVPVVLVAAGLGIYAYIETNSTLANYLLFNYLGNPGL
AEVAVFCAAVCGSGLAFLWFNSHPAEVFMGDVGSLTLGAVLGVIAVMVRQELIFFIMGLLFVVEALSVMLQVGSYKLRNG
KRIFRMAPIHHHFELKGWPETKVVIRFWIISLILFLIGLAAIKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=365, Percent_Identity=52.8767123287671, Blast_Score=373, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 40547; Mature: 40547

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIYLFEWLSHYFKGLEVFSNYISVRIIMISITSLLITLALGRPMISWLQKMQIGQIVRD
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DGPQSHFSKRNTPTMGGVLILSSVIISCLLWGDLTSIYLWILILVVIFFGAIGFFDDYLK
CCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLKHPKGLRAKYKFALQSIFSIVLAIVLFYLLSKNGQMSLSIPFSKSLYIPMGIVIFVV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHH
LAFFIINGSSNAVNLTDGLDGLAIVPVVLVAAGLGIYAYIETNSTLANYLLFNYLGNPGL
HHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCH
AEVAVFCAAVCGSGLAFLWFNSHPAEVFMGDVGSLTLGAVLGVIAVMVRQELIFFIMGLL
HHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVEALSVMLQVGSYKLRNGKRIFRMAPIHHHFELKGWPETKVVIRFWIISLILFLIGLA
HHHHHHHHHHHHCCEEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
AIKVR
HHCCC
>Mature Secondary Structure
MLIYLFEWLSHYFKGLEVFSNYISVRIIMISITSLLITLALGRPMISWLQKMQIGQIVRD
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DGPQSHFSKRNTPTMGGVLILSSVIISCLLWGDLTSIYLWILILVVIFFGAIGFFDDYLK
CCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLKHPKGLRAKYKFALQSIFSIVLAIVLFYLLSKNGQMSLSIPFSKSLYIPMGIVIFVV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHH
LAFFIINGSSNAVNLTDGLDGLAIVPVVLVAAGLGIYAYIETNSTLANYLLFNYLGNPGL
HHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCH
AEVAVFCAAVCGSGLAFLWFNSHPAEVFMGDVGSLTLGAVLGVIAVMVRQELIFFIMGLL
HHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVEALSVMLQVGSYKLRNGKRIFRMAPIHHHFELKGWPETKVVIRFWIISLILFLIGLA
HHHHHHHHHHHHCCEEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
AIKVR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA