Click here to switch to the map view.

The map label for this gene is accB [H]

Identifier: 134302450

GI number: 134302450

Start: 1502106

End: 1502579

Strand: Reverse

Name: accB [H]

Synonym: FTW_1598

Alternate gene names: 134302450

Gene position: 1502579-1502106 (Counterclockwise)

Preceding gene: 134302451

Following gene: 134302449

Centisome position: 79.15

GC content: 37.34

Gene sequence:

>474_bases
ATGGATTTATTAAAAGCAATTGATAGAGTGGCTGAGATTCTTAACTCAAGTGATATAAAGGAAATCAGAATTAAAGATGG
TGGTTCAAGCATTTTTATGACAAAAAATAATACAGCTGCTATTACAAGTGTAGTTTTTGCTGCACCAGTTGCTAGCAATG
TTGCTTCAGCAGCTCCAGCAGTAGCTACTGCTGCTACTTCGGCAGCAGCTCCTAAAGTAAATCTGGCTGAAGAAATAAGC
GGTGAAGAGATCAAGTCTCCAATGGTAGGTACTTTCTATGGCGCATCTTCACCTGATGCTGCTCCTTATGTTAAAGAAGG
TCAAGAAGTCAAAAAAGGCGACGTATTGTGTATCATCGAAGCAATGAAAATCATGAACAAAATTGAAGCAGAAAGAGCAG
GTAAAATTGTTAAAATCATCGCTAAAGATGGTGAGCCTGTTCAATTTGATCAACCTCTATTTATTATTGAATAA

Upstream 100 bases:

>100_bases
GATATAGCTTATGGATGTATATTTGGGTTTGGGCCAAATGGTTACACGCTAGCATTAATAGAAGCAATAAATTACATAAA
TATGAAAGGAGAGTAGAAAA

Downstream 100 bases:

>100_bases
TAAGCAATAAGTGACAATTAAAAATAGAGACTTCAGGTATAAACTTTTTAAAAGGTAATACAAAATGATTAAAAAAGTAC
TGATTGCCAATAGAGGTGAA

Product: acetyl-CoA carboxylase, biotin carboxyl carrier protein

Products: ADP; phosphate; malonyl-CoA

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MDLLKAIDRVAEILNSSDIKEIRIKDGGSSIFMTKNNTAAITSVVFAAPVASNVASAAPAVATAATSAAAPKVNLAEEIS
GEEIKSPMVGTFYGASSPDAAPYVKEGQEVKKGDVLCIIEAMKIMNKIEAERAGKIVKIIAKDGEPVQFDQPLFIIE

Sequences:

>Translated_157_residues
MDLLKAIDRVAEILNSSDIKEIRIKDGGSSIFMTKNNTAAITSVVFAAPVASNVASAAPAVATAATSAAAPKVNLAEEIS
GEEIKSPMVGTFYGASSPDAAPYVKEGQEVKKGDVLCIIEAMKIMNKIEAERAGKIVKIIAKDGEPVQFDQPLFIIE
>Mature_157_residues
MDLLKAIDRVAEILNSSDIKEIRIKDGGSSIFMTKNNTAAITSVVFAAPVASNVASAAPAVATAATSAAAPKVNLAEEIS
GEEIKSPMVGTFYGASSPDAAPYVKEGQEVKKGDVLCIIEAMKIMNKIEAERAGKIVKIIAKDGEPVQFDQPLFIIE

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=162, Percent_Identity=41.358024691358, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: 6.4.1.2

Molecular weight: Translated: 16494; Mature: 16494

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLKAIDRVAEILNSSDIKEIRIKDGGSSIFMTKNNTAAITSVVFAAPVASNVASAAPA
CHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCH
VATAATSAAAPKVNLAEEISGEEIKSPMVGTFYGASSPDAAPYVKEGQEVKKGDVLCIIE
HHHHHHHCCCCCCCHHHHCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEHHHH
AMKIMNKIEAERAGKIVKIIAKDGEPVQFDQPLFIIE
HHHHHHHHHHHHCCCEEEEEECCCCCCEECCCEEEEC
>Mature Secondary Structure
MDLLKAIDRVAEILNSSDIKEIRIKDGGSSIFMTKNNTAAITSVVFAAPVASNVASAAPA
CHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCH
VATAATSAAAPKVNLAEEISGEEIKSPMVGTFYGASSPDAAPYVKEGQEVKKGDVLCIIE
HHHHHHHCCCCCCCHHHHCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEHHHH
AMKIMNKIEAERAGKIVKIIAKDGEPVQFDQPLFIIE
HHHHHHHHHHHHCCCEEEEEECCCCCCEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; acetyl-CoA; HCO3-

Specific reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]