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The map label for this gene is aroQ

Identifier: 134302451

GI number: 134302451

Start: 1502584

End: 1503021

Strand: Reverse

Name: aroQ

Synonym: FTW_1599

Alternate gene names: 134302451

Gene position: 1503021-1502584 (Counterclockwise)

Preceding gene: 134302452

Following gene: 134302450

Centisome position: 79.17

GC content: 30.82

Gene sequence:

>438_bases
ATGGATGTTTTAGTTATTAACGGACCAAATCTTAACTTATTGGGTACTCGACAACCACAGTTTTATGGTCATAAAACTTT
AGCTGATATTAACAATGATTTATTAAAAATTGCCAAGGAAAATAATATAAACATCGATTTCTATCAAAGCAATCATGAGG
GACAAATAATTGATAAAATACAGCAGACAGCCGCAAAAATTATCATTATAAATCCCGCAGCTTTCACGCATACAAGTGTG
GCGATAAGAGATGCTTTTTTAGCTATAAATAAGCCTTTTATTGAAATACATTTGTCTAATATATATAATAGGGAAGAATT
TAGGACTAAATCGTTTCTATCAGATATAGCTTATGGATGTATATTTGGGTTTGGGCCAAATGGTTACACGCTAGCATTAA
TAGAAGCAATAAATTACATAAATATGAAAGGAGAGTAG

Upstream 100 bases:

>100_bases
TACAGGATGTGTGTTTGGAGGTAAGCTTACTTGTTATTGCATCGAGACGGAAAAAAAATACGCAGTAAAAGCACTCAAAA
GTTATAAGGATATATAGAAT

Downstream 100 bases:

>100_bases
AAAAATGGATTTATTAAAAGCAATTGATAGAGTGGCTGAGATTCTTAACTCAAGTGATATAAAGGAAATCAGAATTAAAG
ATGGTGGTTCAAGCATTTTT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDVLVINGPNLNLLGTRQPQFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKIQQTAAKIIIINPAAFTHTSV
AIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGCIFGFGPNGYTLALIEAINYINMKGE

Sequences:

>Translated_145_residues
MDVLVINGPNLNLLGTRQPQFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKIQQTAAKIIIINPAAFTHTSV
AIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGCIFGFGPNGYTLALIEAINYINMKGE
>Mature_145_residues
MDVLVINGPNLNLLGTRQPQFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKIQQTAAKIIIINPAAFTHTSV
AIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGCIFGFGPNGYTLALIEAINYINMKGE

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_FRAT1 (Q14IY5)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_666641.1
- ProteinModelPortal:   Q14IY5
- SMR:   Q14IY5
- STRING:   Q14IY5
- GeneID:   4199434
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF0471
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   FTUL393115:FTF0471-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16330; Mature: 16330

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 97-97 BINDING 71-71 BINDING 77-77 BINDING 84-84 BINDING 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLVINGPNLNLLGTRQPQFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKI
CEEEEEECCCEEEEECCCCCCCCCHHHHHCCHHHEEHECCCCCEEEEEECCCCCHHHHHH
QQTAAKIIIINPAAFTHTSVAIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGC
HHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECHHCCHHHHHHHHHHHHHHHHH
IFGFGPNGYTLALIEAINYINMKGE
EEEECCCCEEEHEEEHHHHEECCCC
>Mature Secondary Structure
MDVLVINGPNLNLLGTRQPQFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKI
CEEEEEECCCEEEEECCCCCCCCCHHHHHCCHHHEEHECCCCCEEEEEECCCCCHHHHHH
QQTAAKIIIINPAAFTHTSVAIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGC
HHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECHHCCHHHHHHHHHHHHHHHHH
IFGFGPNGYTLALIEAINYINMKGE
EEEECCCCEEEHEEEHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA