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The map label for this gene is mraW [H]

Identifier: 134302412

GI number: 134302412

Start: 1453269

End: 1454168

Strand: Reverse

Name: mraW [H]

Synonym: FTW_1548

Alternate gene names: 134302412

Gene position: 1454168-1453269 (Counterclockwise)

Preceding gene: 134302413

Following gene: 134302411

Centisome position: 76.6

GC content: 33.44

Gene sequence:

>900_bases
TTGCAAGAGTCTATTAATGATTTAAATATTAATCCTCAAGGTATTTATATCGATGCAACCTTTGGTAGAGGTGGACATTC
AAAAGCTATTTTAAATAGGCTTACTACAGGGCGTTTGATAGCTTTTGATAAGGATCTTGATGCTATCAGTTATGCTAGGG
AAAATTTCCAGTTTAGTAATTTTGAGATAGTTCACGCAAGTTTTGCTAGTATTTATGACTACTGTTTACAACATAGTCTG
CTTGGTAAAATTGATGGTATAATTATGGATCTTGGGGTTTCTTCACCGCAACTAGATAATGCTGCTAGGGGTTTTAGTTT
TACGCATAATGGACCACTAGATATGCGCATGGACGTTTCTAAAGGTATTACAGCTAGCCAAGCTTTAGAAGAGTTATCGG
TAGATGATCTAAGTTATATATTTAAAGTTTATGGTGAGGAACGTTTTGCAAAAAAAATCGCATTACGTATAAAGGATTAC
ATTCAACAAAATGGTAGTATTAGGACAACATTAGAACTTGCAGAGCTTATTCGTGCAACTATTGGTAAGAAAGAAAAGAA
AAATCCAGCAACACGCTGTTTCCAAGCTTTGAGAATTTATGTTAATAATGAGCTTAAGGATTTAGAAGCTTTGCTAGAAA
ATATTTTAGCAGTTATTAAATCTGGTGGTAGGATAGCTGTTATATCTTTTCATTCATTAGAAGATAGAATTGTGAAACAG
AAATTTAGCGCACTTATAAATCCAAAGCAAGAGCTTAACAGAATTACAAAGATGTTACCGCAAGATAGTAGCCAGATAAA
ACTAAAATGGATTACAAAAAAATCCAAAGCTAATGAAGATGAGCTTAATCAAAATGTTCGCTCAAGAAGTGCTATCTTAA
GGGTGGTCGAAAAGTTATGA

Upstream 100 bases:

>100_bases
CTATACCTAAACTTGGTTCTGGTAAAACTGATTTTTCAAAAGCTAAGAAGTTAACTAATGAATTAGTTAAGGCATAGTTT
AGATGCATTATTCAGTATTG

Downstream 100 bases:

>100_bases
TGTTAACAAATCGTCAAATAAGGGTAAGATTATTTGAATCACTTAAAAATAGTTTCTTTAAAAAAACAGTTGGTATTTCT
TTTGCATTATTATTTATATT

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDYCLQHSL
LGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVDDLSYIFKVYGEERFAKKIALRIKDY
IQQNGSIRTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAVISFHSLEDRIVKQ
KFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL

Sequences:

>Translated_299_residues
MQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDYCLQHSL
LGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVDDLSYIFKVYGEERFAKKIALRIKDY
IQQNGSIRTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAVISFHSLEDRIVKQ
KFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL
>Mature_299_residues
MQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDYCLQHSL
LGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVDDLSYIFKVYGEERFAKKIALRIKDY
IQQNGSIRTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAVISFHSLEDRIVKQ
KFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=337, Percent_Identity=34.7181008902077, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI165377202, Length=162, Percent_Identity=38.2716049382716, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786270, Length=306, Percent_Identity=45.7516339869281, Blast_Score=266, Evalue=9e-73,
Organism=Drosophila melanogaster, GI62472493, Length=321, Percent_Identity=35.202492211838, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571637, Length=321, Percent_Identity=35.202492211838, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 33753; Mature: 33753

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSN
CCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCC
FEIVHASFASIYDYCLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVS
EEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHCCCCCCCCCCCCEEECHH
KGITASQALEELSVDDLSYIFKVYGEERFAKKIALRIKDYIQQNGSIRTTLELAELIRAT
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
IGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAVISFHSLEDRIVKQ
HCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
KFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL
HHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSN
CCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCC
FEIVHASFASIYDYCLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVS
EEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHCCCCCCCCCCCCEEECHH
KGITASQALEELSVDDLSYIFKVYGEERFAKKIALRIKDYIQQNGSIRTTLELAELIRAT
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
IGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAVISFHSLEDRIVKQ
HCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
KFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL
HHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA