Click here to switch to the map view.

The map label for this gene is cdd [H]

Identifier: 134302369

GI number: 134302369

Start: 1396612

End: 1397013

Strand: Direct

Name: cdd [H]

Synonym: FTW_1493

Alternate gene names: 134302369

Gene position: 1396612-1397013 (Clockwise)

Preceding gene: 134302368

Following gene: 134302371

Centisome position: 73.56

GC content: 31.84

Gene sequence:

>402_bases
ATGACTCAAAAACAAGATCAACAACTAATTGAATATGCAAAAGAAGCTTTTAATAATGCATATGCACCATTTTCTGGATT
TAAAGTTGGGGCTGCCTTACTTATGAAGGATGGTAATATCATCAATAGTGCAAATATTGAAACTTCGATTCTAGGCTTAT
CTGTTTGTGCAGAAAGAAATGCTATATTTTATGCTTATAGTCAAGGTTATCGCAAAGATGATATCGTTAAGATTGCAGTA
GTTGCTGATACAGAAAAAGCAATATCACCGTGTGGAGCATGCCGACAGATAATGTCAGAACATCTTAATCTTGACTGCCC
AATTATTTTAACTAATATGAGTGATACTGATAGATTAGATACTAATACTAAAGAACTATTACCTTATATATTCTCTTTAT
AA

Upstream 100 bases:

>100_bases
ACAAAAGTAAATATGATGAAGGTATGTACAATATCATGATGATAATTAAACACTCTATTGAAAATAATTTTTTCAGCTAA
ATAAAAGGTATAAATAAAAA

Downstream 100 bases:

>100_bases
AGAATTCTTAAAAAAATATAAATATTCAAAAGATAACAAATTGCATTATTCAATTTATTATAAGTATTTTGTTTTTGTAG
AGAATTTATTTTGAAATAAA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTQKQDQQLIEYAKEAFNNAYAPFSGFKVGAALLMKDGNIINSANIETSILGLSVCAERNAIFYAYSQGYRKDDIVKIAV
VADTEKAISPCGACRQIMSEHLNLDCPIILTNMSDTDRLDTNTKELLPYIFSL

Sequences:

>Translated_133_residues
MTQKQDQQLIEYAKEAFNNAYAPFSGFKVGAALLMKDGNIINSANIETSILGLSVCAERNAIFYAYSQGYRKDDIVKIAV
VADTEKAISPCGACRQIMSEHLNLDCPIILTNMSDTDRLDTNTKELLPYIFSL
>Mature_132_residues
TQKQDQQLIEYAKEAFNNAYAPFSGFKVGAALLMKDGNIINSANIETSILGLSVCAERNAIFYAYSQGYRKDDIVKIAVV
ADTEKAISPCGACRQIMSEHLNLDCPIILTNMSDTDRLDTNTKELLPYIFSL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=127, Percent_Identity=43.3070866141732, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17551074, Length=127, Percent_Identity=44.0944881889764, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=40.9448818897638, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323274, Length=128, Percent_Identity=30.46875, Blast_Score=76, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582741, Length=131, Percent_Identity=41.2213740458015, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920920, Length=111, Percent_Identity=39.6396396396396, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582744, Length=140, Percent_Identity=35, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14735; Mature: 14604

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKQDQQLIEYAKEAFNNAYAPFSGFKVGAALLMKDGNIINSANIETSILGLSVCAERN
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEEECCCEEECCCCCHHHHHHHHHCCCC
AIFYAYSQGYRKDDIVKIAVVADTEKAISPCGACRQIMSEHLNLDCPIILTNMSDTDRLD
EEEEEECCCCCCCCEEEEEEEECCHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
TNTKELLPYIFSL
CCHHHHHHHHHCC
>Mature Secondary Structure 
TQKQDQQLIEYAKEAFNNAYAPFSGFKVGAALLMKDGNIINSANIETSILGLSVCAERN
CCHHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEEECCCEEECCCCCHHHHHHHHHCCCC
AIFYAYSQGYRKDDIVKIAVVADTEKAISPCGACRQIMSEHLNLDCPIILTNMSDTDRLD
EEEEEECCCCCCCCEEEEEEEECCHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
TNTKELLPYIFSL
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]