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The map label for this gene is udp [H]

Identifier: 134302368

GI number: 134302368

Start: 1395788

End: 1396591

Strand: Direct

Name: udp [H]

Synonym: FTW_1492

Alternate gene names: 134302368

Gene position: 1395788-1396591 (Clockwise)

Preceding gene: 134302366

Following gene: 134302369

Centisome position: 73.52

GC content: 33.33

Gene sequence:

>804_bases
ATGAGTAATATAAATATTGCTAATAAACGTGTTGCTAAAAGTGATGTTCTTTATCATATTGCACTAAGTGAAGAAATGAT
AAACAGTGCAACAATTGCCATTCTTCCAGGCGATCCTAAAAGATCGGAATATTTAGCAAAAATGTTAGATACTGATGCTA
CTTTCTTAGCATCTAACCGAGAATATACCTCATATCTAGCAAAAGTTGCCAACCAAAATGTTATTGTAATATCAACAGGT
ATGGGTGGGCCATCAGTAGCAATATGTATAGAAGAGTTAGCAATGATTGGCGTTAAGAAATTCATACGAGTAGGCACATG
TGGAGCAATTCAAGAAAATATTGAAATTGGTGACTTAATCTTAAGTACAGCGTCTGTAAGATTAGATGGAACCTCATATC
ACTATGCTCCAATTGAATACCCTGCTGTCGCAAGCTTCAGTCTTAATACTTCTCTATATCGTTCAGCTCAGACACTTAAT
AAAAAAATCCACTGTGGTATAACTGGTTCATCTGATACATTCTTCCCTGGACAAGATAGAAAAGATAATTATAGTGGTTA
TATTAGAAGACATTTCATAAATTCTCTCAATGAATGGCGTAAATTAAATGTCCTTAATTTTGAAATGGAATCATCAGCAT
TATTTACAGTATGTGCCACATTTGGTTTAGAGGCAAGCTGCCTATGCACAGTACTTGCTAAAAGAACTACTTCTGAATAC
ATCGACAAAAGTAAATATGATGAAGGTATGTACAATATCATGATGATAATTAAACACTCTATTGAAAATAATTTTTTCAG
CTAA

Upstream 100 bases:

>100_bases
TTTTGCGGTAATTATAAAAAATATAGTTGATTTATTCTATTTAAAATACAATAAGAGTAGAATTATTTTTAGATAAAAAA
TATTTTGGTTCTAGAATTCT

Downstream 100 bases:

>100_bases
ATAAAAGGTATAAATAAAAAATGACTCAAAAACAAGATCAACAACTAATTGAATATGCAAAAGAAGCTTTTAATAATGCA
TATGCACCATTTTCTGGATT

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSNINIANKRVAKSDVLYHIALSEEMINSATIAILPGDPKRSEYLAKMLDTDATFLASNREYTSYLAKVANQNVIVISTG
MGGPSVAICIEELAMIGVKKFIRVGTCGAIQENIEIGDLILSTASVRLDGTSYHYAPIEYPAVASFSLNTSLYRSAQTLN
KKIHCGITGSSDTFFPGQDRKDNYSGYIRRHFINSLNEWRKLNVLNFEMESSALFTVCATFGLEASCLCTVLAKRTTSEY
IDKSKYDEGMYNIMMIIKHSIENNFFS

Sequences:

>Translated_267_residues
MSNINIANKRVAKSDVLYHIALSEEMINSATIAILPGDPKRSEYLAKMLDTDATFLASNREYTSYLAKVANQNVIVISTG
MGGPSVAICIEELAMIGVKKFIRVGTCGAIQENIEIGDLILSTASVRLDGTSYHYAPIEYPAVASFSLNTSLYRSAQTLN
KKIHCGITGSSDTFFPGQDRKDNYSGYIRRHFINSLNEWRKLNVLNFEMESSALFTVCATFGLEASCLCTVLAKRTTSEY
IDKSKYDEGMYNIMMIIKHSIENNFFS
>Mature_266_residues
SNINIANKRVAKSDVLYHIALSEEMINSATIAILPGDPKRSEYLAKMLDTDATFLASNREYTSYLAKVANQNVIVISTGM
GGPSVAICIEELAMIGVKKFIRVGTCGAIQENIEIGDLILSTASVRLDGTSYHYAPIEYPAVASFSLNTSLYRSAQTLNK
KIHCGITGSSDTFFPGQDRKDNYSGYIRRHFINSLNEWRKLNVLNFEMESSALFTVCATFGLEASCLCTVLAKRTTSEYI
DKSKYDEGMYNIMMIIKHSIENNFFS

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=229, Percent_Identity=48.9082969432314, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1790844, Length=212, Percent_Identity=26.4150943396226, Blast_Score=89, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24650443, Length=267, Percent_Identity=25.4681647940075, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650445, Length=267, Percent_Identity=25.4681647940075, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 29648; Mature: 29517

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNINIANKRVAKSDVLYHIALSEEMINSATIAILPGDPKRSEYLAKMLDTDATFLASNR
CCCCCCCHHHHHHHHEEEEEEECHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEECCC
EYTSYLAKVANQNVIVISTGMGGPSVAICIEELAMIGVKKFIRVGTCGAIQENIEIGDLI
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHH
LSTASVRLDGTSYHYAPIEYPAVASFSLNTSLYRSAQTLNKKIHCGITGSSDTFFPGQDR
EEHEEEEECCCEEEECCCCCCCEEEEECCHHHHHHHHHHCCEEEEEEECCCCCCCCCCCC
KDNYSGYIRRHFINSLNEWRKLNVLNFEMESSALFTVCATFGLEASCLCTVLAKRTTSEY
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IDKSKYDEGMYNIMMIIKHSIENNFFS
HHHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNINIANKRVAKSDVLYHIALSEEMINSATIAILPGDPKRSEYLAKMLDTDATFLASNR
CCCCCCHHHHHHHHEEEEEEECHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEECCC
EYTSYLAKVANQNVIVISTGMGGPSVAICIEELAMIGVKKFIRVGTCGAIQENIEIGDLI
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHH
LSTASVRLDGTSYHYAPIEYPAVASFSLNTSLYRSAQTLNKKIHCGITGSSDTFFPGQDR
EEHEEEEECCCEEEECCCCCCCEEEEECCHHHHHHHHHHCCEEEEEEECCCCCCCCCCCC
KDNYSGYIRRHFINSLNEWRKLNVLNFEMESSALFTVCATFGLEASCLCTVLAKRTTSEY
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IDKSKYDEGMYNIMMIIKHSIENNFFS
HHHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]