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The map label for this gene is pqqL [C]

Identifier: 134302363

GI number: 134302363

Start: 1391262

End: 1392515

Strand: Direct

Name: pqqL [C]

Synonym: FTW_1487

Alternate gene names: 134302363

Gene position: 1391262-1392515 (Clockwise)

Preceding gene: 134302362

Following gene: 134302364

Centisome position: 73.28

GC content: 32.06

Gene sequence:

>1254_bases
ATGAGTATCGAAAAATATTCCCTAAATAATAATTTAGATATCTATATAAAAAAAGATATACGAGCACCTGTGGTTTTGGC
ACAAATATGGTATAAAGTTGGCTCAATATACGAGCCTGAAAAACTTACTGGCATATCTCACATGCTTGAACATATGATGT
TTAAAGGTACAAACAAATATTCAAAAGAGGAGTTAAATAGCATAGTTGAAAATAATGGCGGTATCCAAAATGCTTTCACA
AGCTTTGACTACACTGCATATTACCAGTTTTGGCATAAGAAAAATCTCGAATTAAGCTTATCTATAGAATCATCACGAAT
GAGTGATTTATTGTTTGATGAAAATGAGTTTATGCCAGAAAAGAAGGTAGTTTTAGAAGAGAGAAGCTTACGGGTTGATG
ATAAAGCTTTTAGTTATGCTTTTGAACAATTTATGCAACTTGCGTATCAAAAAAACTCGCGTCACACTCCTGTTATTGGC
TGGCGTGAAGACATTAAAAACTATACTCTTGATAATCTCAAAAAATGGTATCAACAAAATTATGCTCCAAATAATTCAAG
TATTGTTTTAGTTGGAGACATTGATACAGCTTCAGCATTATCAATGGCTAAGGATTATTTTGCTAGTATCCCAAAATCTC
AACTAATTGCTACAAAAAAAGAGCCTAGCTTAATTAATATTGGTCATAGACATTTAAAAGTAAAAAAATCACCAAATGAT
ACTGCCGCATTAATATTAGGATATATCACACCTTCTCTAACCACAGATTATCAAGATAATGATCCGTTTGCCCTACTAGT
TCTTAATAATATCCTTGGTAATGCTGATGCATCAATACTGCAACAACAGCTAGTAAGAGAAGAAAATCTATGTTGTCATA
TCAATAGTGAGTATTCACCATTTATAAAAGGTGAAGATATTTTCACAATTACAGCTATAGCGAATCATGCTCAAGAGCTA
GATGGTATCGAAGACAAAATACAAGGTATTATAGCTAAGCTTAGGAATAAAGGTATTACTACAGAGCAGCTTAATCGAGC
AAAAGTAACTATCAAAGCTGATAAAGTATTTGCCATGGATTCACTCGAAACTCAAGCAAATCTGATAGGTTCTTTAGCTA
GTATTAACCTAGATGTTGACTACTATAAATACCTTGAGAAACTTTATGATGTAACAGTTAGTGACATTAATCGTGTACTT
GATAGATATTTTGATAAACAAAACCTTGCATCTCTACATTTATTAAGGGATTAA

Upstream 100 bases:

>100_bases
TTACACTTACCACCAATACTTGGTGCTGCAGGGCCAACTGTTATAGCGCTAATATTGTTAATATATTTATTTATAAAATC
AAAAGAAACATAAAAATAAT

Downstream 100 bases:

>100_bases
AAAATCATGATCTATAAATTTAATATTGATAATACACCCATATACTTTCAAGAATCCCACAACTTACCAATGTTAGATAT
TCAACTTAATTTCAGAGCTG

Product: M16 family metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSIYEPEKLTGISHMLEHMMFKGTNKYSKEELNSIVENNGGIQNAFT
SFDYTAYYQFWHKKNLELSLSIESSRMSDLLFDENEFMPEKKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIG
WREDIKNYTLDNLKKWYQQNYAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKEPSLINIGHRHLKVKKSPND
TAALILGYITPSLTTDYQDNDPFALLVLNNILGNADASILQQQLVREENLCCHINSEYSPFIKGEDIFTITAIANHAQEL
DGIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMDSLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVL
DRYFDKQNLASLHLLRD

Sequences:

>Translated_417_residues
MSIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSIYEPEKLTGISHMLEHMMFKGTNKYSKEELNSIVENNGGIQNAFT
SFDYTAYYQFWHKKNLELSLSIESSRMSDLLFDENEFMPEKKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIG
WREDIKNYTLDNLKKWYQQNYAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKEPSLINIGHRHLKVKKSPND
TAALILGYITPSLTTDYQDNDPFALLVLNNILGNADASILQQQLVREENLCCHINSEYSPFIKGEDIFTITAIANHAQEL
DGIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMDSLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVL
DRYFDKQNLASLHLLRD
>Mature_416_residues
SIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSIYEPEKLTGISHMLEHMMFKGTNKYSKEELNSIVENNGGIQNAFTS
FDYTAYYQFWHKKNLELSLSIESSRMSDLLFDENEFMPEKKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIGW
REDIKNYTLDNLKKWYQQNYAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKEPSLINIGHRHLKVKKSPNDT
AALILGYITPSLTTDYQDNDPFALLVLNNILGNADASILQQQLVREENLCCHINSEYSPFIKGEDIFTITAIANHAQELD
GIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMDSLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVLD
RYFDKQNLASLHLLRD

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=279, Percent_Identity=27.9569892473118, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI46593007, Length=275, Percent_Identity=22.9090909090909, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1787770, Length=204, Percent_Identity=29.9019607843137, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71999683, Length=252, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17553678, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=255, Percent_Identity=26.2745098039216, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21357875, Length=409, Percent_Identity=23.4718826405868, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646943, Length=409, Percent_Identity=23.4718826405868, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47780; Mature: 47649

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSIYEPEKLTGISHMLEHMMFKGTNKY
CCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
SKEELNSIVENNGGIQNAFTSFDYTAYYQFWHKKNLELSLSIESSRMSDLLFDENEFMPE
CHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCCCH
KKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIGWREDIKNYTLDNLKKWYQQN
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHCCCHHHHHHHHHHC
YAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKEPSLINIGHRHLKVKKSPND
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHEEECCCCCEEECCCEEEEEECCCCC
TAALILGYITPSLTTDYQDNDPFALLVLNNILGNADASILQQQLVREENLCCHINSEYSP
CCEEEEEECCCCCCCCCCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCC
FIKGEDIFTITAIANHAQELDGIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMD
CCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHCCCEEEEEEECCEEEHH
SLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVLDRYFDKQNLASLHLLRD
HHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHEEECC
>Mature Secondary Structure 
SIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSIYEPEKLTGISHMLEHMMFKGTNKY
CCCEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
SKEELNSIVENNGGIQNAFTSFDYTAYYQFWHKKNLELSLSIESSRMSDLLFDENEFMPE
CHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCCCH
KKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIGWREDIKNYTLDNLKKWYQQN
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHCCCHHHHHHHHHHC
YAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKEPSLINIGHRHLKVKKSPND
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHEEECCCCCEEECCCEEEEEECCCCC
TAALILGYITPSLTTDYQDNDPFALLVLNNILGNADASILQQQLVREENLCCHINSEYSP
CCEEEEEECCCCCCCCCCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCC
FIKGEDIFTITAIANHAQELDGIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMD
CCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHCCCEEEEEEECCEEEHH
SLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVLDRYFDKQNLASLHLLRD
HHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]