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The map label for this gene is nagA [H]

Identifier: 134302155

GI number: 134302155

Start: 1142504

End: 1143637

Strand: Reverse

Name: nagA [H]

Synonym: FTW_1211

Alternate gene names: 134302155

Gene position: 1143637-1142504 (Counterclockwise)

Preceding gene: 134302158

Following gene: 134302154

Centisome position: 60.24

GC content: 35.45

Gene sequence:

>1134_bases
ATGCAAAGCTATATTCTAAAAGGTGGCAAAATTTATAGCCAAAATGATTTTGAAGCTAAGGATATTGTAGTTAAAGATAA
TGTTATTAGTGATATAGTTGATGATGCTGATCCAGCAGCTTTTAATTTACCTATTATTGAGCTAAGTGGTGATGATTATG
TGATACCTGGTTTTATCGATATCCATATCCATGGTTCAAAAGGTGCTGATGTTATGGATGGAGATGTTGATGCCTTAGCT
GTAATCTCTAAATCACTATATACACAAGGAGTAACTAGCTATCTTGCGACCACAATGACAGCAGCAAATGAGCAAATACT
CAAAGCAATGCGTGCTATCAAAGATTATAATTCTCAAACCCACTTGGATAGTGCAAAAATTGTTGGTGTTCATCTAGAGG
GGCCATTTATATCACCAGGTAAGATTGGTGCACAAAATCCCAATTACCTCCAAGAAGCAGATGTTACTAAAATGGCAAGT
TGGCATAATGCTTGTGATAGTTTAATCAAAAAAATCACTATTGCCCCAGAGATTAAGAATGCTAATAAAGTAATCGAGTT
TTGTAATTCTAAAAATATAATTAGTTCAATAGGTCATACTAGCTGTACAATGGCTCAAGCTCTAAATGCGATAGAGCAGG
GTTGTACACATGCGACACATCTATTTAATGCAATGAGTCCGATTGAACATCGCAATCCTGGTGCGGCAACAGCGTTATTA
ATGTCAAAAAAAGTTTTAGCAGAGCTAATAGTTGATGGTATTCATCTACATCCTGATATGGTTAAGTTTACCTATGCGAT
AAAAGGTAGTGATAAAATCGCACTAATCACTGATGCGATGTCTGCTCAAAGTGCTGGTGAAGGTGTATTTGAATTAGGTG
GTCAGAAAGTCATAGTTAAAGATGGTCAGGCAAGGTTAGAGAATGGTGTGTTTGCAGGAAGTGTCTTGACAATGAATAAG
GCACTAGAGAATGTTTTGAAATTTACAAATTGTAGTCTCTATGATGCTGTGAAAATGACAAGTACAAATCAAGCTAAGTC
ATTAGGGTTTAAAAAAGGTCAAATCAAAGGAGGCTTTGATGCTGAGTTTGTAATTCTCAATAAAAATTATCAAGTTAAAC
AAGTTATTGGTTAG

Upstream 100 bases:

>100_bases
GTGGCTTTATGCATATGCCCGGGAAACCAATGTAACATTGTAGATAAAAATTATAAATTTAGTTAATATAGGACAAGATT
TTACCGATTAGGTCTGATAT

Downstream 100 bases:

>100_bases
AAAATGAATTTTTTATTATTAGATACATCAAGTAAGTATTGTTCAGTGGTGTTATCAGCCGCTGGTGAATTGTATAATGA
TACGCGTGAGATACCACGCC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MQSYILKGGKIYSQNDFEAKDIVVKDNVISDIVDDADPAAFNLPIIELSGDDYVIPGFIDIHIHGSKGADVMDGDVDALA
VISKSLYTQGVTSYLATTMTAANEQILKAMRAIKDYNSQTHLDSAKIVGVHLEGPFISPGKIGAQNPNYLQEADVTKMAS
WHNACDSLIKKITIAPEIKNANKVIEFCNSKNIISSIGHTSCTMAQALNAIEQGCTHATHLFNAMSPIEHRNPGAATALL
MSKKVLAELIVDGIHLHPDMVKFTYAIKGSDKIALITDAMSAQSAGEGVFELGGQKVIVKDGQARLENGVFAGSVLTMNK
ALENVLKFTNCSLYDAVKMTSTNQAKSLGFKKGQIKGGFDAEFVILNKNYQVKQVIG

Sequences:

>Translated_377_residues
MQSYILKGGKIYSQNDFEAKDIVVKDNVISDIVDDADPAAFNLPIIELSGDDYVIPGFIDIHIHGSKGADVMDGDVDALA
VISKSLYTQGVTSYLATTMTAANEQILKAMRAIKDYNSQTHLDSAKIVGVHLEGPFISPGKIGAQNPNYLQEADVTKMAS
WHNACDSLIKKITIAPEIKNANKVIEFCNSKNIISSIGHTSCTMAQALNAIEQGCTHATHLFNAMSPIEHRNPGAATALL
MSKKVLAELIVDGIHLHPDMVKFTYAIKGSDKIALITDAMSAQSAGEGVFELGGQKVIVKDGQARLENGVFAGSVLTMNK
ALENVLKFTNCSLYDAVKMTSTNQAKSLGFKKGQIKGGFDAEFVILNKNYQVKQVIG
>Mature_377_residues
MQSYILKGGKIYSQNDFEAKDIVVKDNVISDIVDDADPAAFNLPIIELSGDDYVIPGFIDIHIHGSKGADVMDGDVDALA
VISKSLYTQGVTSYLATTMTAANEQILKAMRAIKDYNSQTHLDSAKIVGVHLEGPFISPGKIGAQNPNYLQEADVTKMAS
WHNACDSLIKKITIAPEIKNANKVIEFCNSKNIISSIGHTSCTMAQALNAIEQGCTHATHLFNAMSPIEHRNPGAATALL
MSKKVLAELIVDGIHLHPDMVKFTYAIKGSDKIALITDAMSAQSAGEGVFELGGQKVIVKDGQARLENGVFAGSVLTMNK
ALENVLKFTNCSLYDAVKMTSTNQAKSLGFKKGQIKGGFDAEFVILNKNYQVKQVIG

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI224922791, Length=422, Percent_Identity=27.9620853080569, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI21361513, Length=422, Percent_Identity=27.9620853080569, Blast_Score=152, Evalue=6e-37,
Organism=Escherichia coli, GI1786892, Length=382, Percent_Identity=29.5811518324607, Blast_Score=170, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17553768, Length=337, Percent_Identity=32.9376854599407, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI19920392, Length=336, Percent_Identity=32.1428571428571, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI281361140, Length=349, Percent_Identity=30.945558739255, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40582; Mature: 40582

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSYILKGGKIYSQNDFEAKDIVVKDNVISDIVDDADPAAFNLPIIELSGDDYVIPGFID
CCCEEECCCEEECCCCCCCCEEEEECHHHHHHHCCCCCCEEECEEEEECCCCEEECCEEE
IHIHGSKGADVMDGDVDALAVISKSLYTQGVTSYLATTMTAANEQILKAMRAIKDYNSQT
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HLDSAKIVGVHLEGPFISPGKIGAQNPNYLQEADVTKMASWHNACDSLIKKITIAPEIKN
CCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
ANKVIEFCNSKNIISSIGHTSCTMAQALNAIEQGCTHATHLFNAMSPIEHRNPGAATALL
HHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHH
MSKKVLAELIVDGIHLHPDMVKFTYAIKGSDKIALITDAMSAQSAGEGVFELGGQKVIVK
HHHHHHHHHHHCCCCCCCCEEEEEEEEECCCEEEEEECCHHHCCCCCCHHHCCCCEEEEE
DGQARLENGVFAGSVLTMNKALENVLKFTNCSLYDAVKMTSTNQAKSLGFKKGQIKGGFD
CCHHHHHCCEEECHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHCCCCCCCCCCCCC
AEFVILNKNYQVKQVIG
EEEEEECCCCCCCCCCC
>Mature Secondary Structure
MQSYILKGGKIYSQNDFEAKDIVVKDNVISDIVDDADPAAFNLPIIELSGDDYVIPGFID
CCCEEECCCEEECCCCCCCCEEEEECHHHHHHHCCCCCCEEECEEEEECCCCEEECCEEE
IHIHGSKGADVMDGDVDALAVISKSLYTQGVTSYLATTMTAANEQILKAMRAIKDYNSQT
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HLDSAKIVGVHLEGPFISPGKIGAQNPNYLQEADVTKMASWHNACDSLIKKITIAPEIKN
CCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
ANKVIEFCNSKNIISSIGHTSCTMAQALNAIEQGCTHATHLFNAMSPIEHRNPGAATALL
HHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHH
MSKKVLAELIVDGIHLHPDMVKFTYAIKGSDKIALITDAMSAQSAGEGVFELGGQKVIVK
HHHHHHHHHHHCCCCCCCCEEEEEEEEECCCEEEEEECCHHHCCCCCCHHHCCCCEEEEE
DGQARLENGVFAGSVLTMNKALENVLKFTNCSLYDAVKMTSTNQAKSLGFKKGQIKGGFD
CCHHHHHCCEEECHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHCCCCCCCCCCCCC
AEFVILNKNYQVKQVIG
EEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]