Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 134302065

GI number: 134302065

Start: 1041274

End: 1042704

Strand: Reverse

Name: ppiD [H]

Synonym: FTW_1101

Alternate gene names: 134302065

Gene position: 1042704-1041274 (Counterclockwise)

Preceding gene: 134302066

Following gene: 134302064

Centisome position: 54.92

GC content: 28.3

Gene sequence:

>1431_bases
ATGTTACAGTCTTTTAATGATAGACTCAAAGGTCCTTTTACATGGATTGTGGTTATCTCGATAAGCTTTATTTTTGTAAT
TTCTGGAATGACATTCTTTTTTACAAATATTGGTAGTAGAGCATATGTTGCTAAAGTTGGTGATAATGAAATAAGCTCAC
AACAATTCCAACAATATGCTCAAAGTGCTACTACAGAAGAACAAAAGAGAGCTATTTTATCTCAAATGATAGATCAGTAT
TTGATATTAGCCGATGCACAACGCCATGATATTGTAGTGTCAAAACTAGCGCTACAATCAGCAATATTTACTAACCCAAT
GTTCTTTGATAAAGATGGAAAGTTTTCTGCTGAAAAGCTAAAACAGGTTGTAGCTTATTTAGGTGGAATGGATAAACTTG
AGCAGATATTAGCTCAAAATATTCAAGCGACTATAATTCCTAAAACTATAGTAGATACATCTATTGTTACAGATTATGAT
ACTAAGTTACTTAATAGTATATACTCTGTGAATAAGTATATAGACTATCTCAAGGTTTCTCCAACAGATTTTAAATCACA
AATTAAACCAAGCCAACAAGATTTACAAAGCTATTATGATAGTCATAAAAATGAGTATATAACACCAGCACAAAAGACAA
TTAGCTACTTTATAATTACAAAAGATAATTTTGTGCTTAAAAATAAAATTAGTGAAGATGAAATAAAAGCATATTATCAA
GCACATAAAGAATTGTTCAAAGATTTTGATAATAATGCCAAGTCTACTATTCAAAAGATAATCCAAAATAGGCATGCCTT
AGAGCAGTTTAATGAGTACACACAAAATATTGATAGTATTAAGTATACTAAATTAGAGAAACAATTTGGCAAAGCTAAAA
CAGCTACAATTGTTGATAATAATGATACGACAATTAGTAATGTTGCTAATAGCCAATTTTTTATAAACTCAGATAAGTAT
GCAACTATTACTATAGCTGATAATAAGCTTTTAGTTTATCAAGTAGATAATTCGATCAAAGCAACTCAGCAAAAACTAGC
TGATATTAAGGATAAAATTTCAAAGGCATATATTGAGCAAAAATCTCAACAATTTGCTTTACAGCATGCTCAAAACCTTT
TAAATGATTTAACTAGCGGAAAGAAGATAGATAAGAGCTTTAAACAAGCTACAATAAATAGTGATTCACAAGCTTTTGGT
AAAGATTTTAATGATTATGTAATGTTTAATAGCAATAATCAATATCATGATTATAAGACTGATAATGGTGATATCTATAT
CTATAAGGTGACTAAAATCGAGCCAATAACAGATAAAACTACTCAAGTACCTAGTCAAGTTATTGATGCGTATAAACAAG
AAGAATTAAACTTTTATTTACAAGTAATTAAACAACAAATTCCAATTCAAGTTAATTATAAAAATATTTAG

Upstream 100 bases:

>100_bases
AAAAAGTAATTTTTTTAAAGGCATGCTTAACAGTATGCCTTTTTTTTATCTATAATATTTACAAGTTAATTAAATTACTC
ATTAATTAAGGTTAATAAAA

Downstream 100 bases:

>100_bases
ATGAGCAAATTAATCTATGGTTTGGCTGGACCAACAGCTTCTGGTAAAACTTCATTATCAATATTGTTAGCTAAAAAAAT
TAATGCAGAAATTATTAGTG

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MLQSFNDRLKGPFTWIVVISISFIFVISGMTFFFTNIGSRAYVAKVGDNEISSQQFQQYAQSATTEEQKRAILSQMIDQY
LILADAQRHDIVVSKLALQSAIFTNPMFFDKDGKFSAEKLKQVVAYLGGMDKLEQILAQNIQATIIPKTIVDTSIVTDYD
TKLLNSIYSVNKYIDYLKVSPTDFKSQIKPSQQDLQSYYDSHKNEYITPAQKTISYFIITKDNFVLKNKISEDEIKAYYQ
AHKELFKDFDNNAKSTIQKIIQNRHALEQFNEYTQNIDSIKYTKLEKQFGKAKTATIVDNNDTTISNVANSQFFINSDKY
ATITIADNKLLVYQVDNSIKATQQKLADIKDKISKAYIEQKSQQFALQHAQNLLNDLTSGKKIDKSFKQATINSDSQAFG
KDFNDYVMFNSNNQYHDYKTDNGDIYIYKVTKIEPITDKTTQVPSQVIDAYKQEELNFYLQVIKQQIPIQVNYKNI

Sequences:

>Translated_476_residues
MLQSFNDRLKGPFTWIVVISISFIFVISGMTFFFTNIGSRAYVAKVGDNEISSQQFQQYAQSATTEEQKRAILSQMIDQY
LILADAQRHDIVVSKLALQSAIFTNPMFFDKDGKFSAEKLKQVVAYLGGMDKLEQILAQNIQATIIPKTIVDTSIVTDYD
TKLLNSIYSVNKYIDYLKVSPTDFKSQIKPSQQDLQSYYDSHKNEYITPAQKTISYFIITKDNFVLKNKISEDEIKAYYQ
AHKELFKDFDNNAKSTIQKIIQNRHALEQFNEYTQNIDSIKYTKLEKQFGKAKTATIVDNNDTTISNVANSQFFINSDKY
ATITIADNKLLVYQVDNSIKATQQKLADIKDKISKAYIEQKSQQFALQHAQNLLNDLTSGKKIDKSFKQATINSDSQAFG
KDFNDYVMFNSNNQYHDYKTDNGDIYIYKVTKIEPITDKTTQVPSQVIDAYKQEELNFYLQVIKQQIPIQVNYKNI
>Mature_476_residues
MLQSFNDRLKGPFTWIVVISISFIFVISGMTFFFTNIGSRAYVAKVGDNEISSQQFQQYAQSATTEEQKRAILSQMIDQY
LILADAQRHDIVVSKLALQSAIFTNPMFFDKDGKFSAEKLKQVVAYLGGMDKLEQILAQNIQATIIPKTIVDTSIVTDYD
TKLLNSIYSVNKYIDYLKVSPTDFKSQIKPSQQDLQSYYDSHKNEYITPAQKTISYFIITKDNFVLKNKISEDEIKAYYQ
AHKELFKDFDNNAKSTIQKIIQNRHALEQFNEYTQNIDSIKYTKLEKQFGKAKTATIVDNNDTTISNVANSQFFINSDKY
ATITIADNKLLVYQVDNSIKATQQKLADIKDKISKAYIEQKSQQFALQHAQNLLNDLTSGKKIDKSFKQATINSDSQAFG
KDFNDYVMFNSNNQYHDYKTDNGDIYIYKVTKIEPITDKTTQVPSQVIDAYKQEELNFYLQVIKQQIPIQVNYKNI

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=252, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 54746; Mature: 54746

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQSFNDRLKGPFTWIVVISISFIFVISGMTFFFTNIGSRAYVAKVGDNEISSQQFQQYA
CCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
QSATTEEQKRAILSQMIDQYLILADAQRHDIVVSKLALQSAIFTNPMFFDKDGKFSAEKL
HHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHH
KQVVAYLGGMDKLEQILAQNIQATIIPKTIVDTSIVTDYDTKLLNSIYSVNKYIDYLKVS
HHHHHHHCCHHHHHHHHHCCCCEEECCHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHCCC
PTDFKSQIKPSQQDLQSYYDSHKNEYITPAQKTISYFIITKDNFVLKNKISEDEIKAYYQ
CCCHHHHCCCCHHHHHHHHHCCCCCCCCCHHHCEEEEEEECCCEEEECCCCHHHHHHHHH
AHKELFKDFDNNAKSTIQKIIQNRHALEQFNEYTQNIDSIKYTKLEKQFGKAKTATIVDN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECC
NDTTISNVANSQFFINSDKYATITIADNKLLVYQVDNSIKATQQKLADIKDKISKAYIEQ
CCCCHHHCCCCEEEEECCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KSQQFALQHAQNLLNDLTSGKKIDKSFKQATINSDSQAFGKDFNDYVMFNSNNQYHDYKT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCCCCCEEEECCCCCCCCEEC
DNGDIYIYKVTKIEPITDKTTQVPSQVIDAYKQEELNFYLQVIKQQIPIQVNYKNI
CCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
>Mature Secondary Structure
MLQSFNDRLKGPFTWIVVISISFIFVISGMTFFFTNIGSRAYVAKVGDNEISSQQFQQYA
CCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
QSATTEEQKRAILSQMIDQYLILADAQRHDIVVSKLALQSAIFTNPMFFDKDGKFSAEKL
HHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHH
KQVVAYLGGMDKLEQILAQNIQATIIPKTIVDTSIVTDYDTKLLNSIYSVNKYIDYLKVS
HHHHHHHCCHHHHHHHHHCCCCEEECCHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHCCC
PTDFKSQIKPSQQDLQSYYDSHKNEYITPAQKTISYFIITKDNFVLKNKISEDEIKAYYQ
CCCHHHHCCCCHHHHHHHHHCCCCCCCCCHHHCEEEEEEECCCEEEECCCCHHHHHHHHH
AHKELFKDFDNNAKSTIQKIIQNRHALEQFNEYTQNIDSIKYTKLEKQFGKAKTATIVDN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECC
NDTTISNVANSQFFINSDKYATITIADNKLLVYQVDNSIKATQQKLADIKDKISKAYIEQ
CCCCHHHCCCCEEEEECCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KSQQFALQHAQNLLNDLTSGKKIDKSFKQATINSDSQAFGKDFNDYVMFNSNNQYHDYKT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCCCCCEEEECCCCCCCCEEC
DNGDIYIYKVTKIEPITDKTTQVPSQVIDAYKQEELNFYLQVIKQQIPIQVNYKNI
CCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]