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The map label for this gene is hflK [H]

Identifier: 134302060

GI number: 134302060

Start: 1036107

End: 1037174

Strand: Reverse

Name: hflK [H]

Synonym: FTW_1096

Alternate gene names: 134302060

Gene position: 1037174-1036107 (Counterclockwise)

Preceding gene: 134302062

Following gene: 134302059

Centisome position: 54.63

GC content: 33.99

Gene sequence:

>1068_bases
ATGATTAAAAAACTAAAACAAAAATGGTTTTGGAGTAAAAATTCGGAGCAGGGACCACCGGATTTAGAAGAAATGATTAA
AAGATTCTTTGGCAAAAAGAATAAAACTGATAATGATGATAATGAGAGTATATATTCAAAAAATGCTAACAAAAAACAAT
CAACATTCAATAAGCCACCGATTGCTAAAATAGTTACAATAATAGTAGCTTTGCTTATAGTTGCATGGGTTGGTTTTGGT
TTTTATGTTGTGCAGCCAGCTGAGCAAGCTATAGTACTTAGATTAGGTAAGTTTTCTAAATTAGTGGAGCCTGGTCTACA
TTGGCATCCCTTGGGTATTGATAAGGTTTATAAAGAAAATGTCCAAGAGTTGAAAACCATTCCTCTAAAGCGTGATATGC
TGACATCTGAGGAGAATATTGTGCATATTTCTTTCACAGTTCAATATCGTATTGCTGATTTAGAAAAATACTTATTTGCT
AATACAAATCCTACTTTGTTATTACAACAAGCTTTAGAAAGTGCAGTTAGACAAGTAGTTGGTGAGAATAAACTAGAGCA
AATATTAACAACTAATCGTGCCGTAATTACTCAGCAGGTTAGAAAAGAAATGGAAGCATTACTAGAAAAATATAATTCAG
GTATTTATGTTAGTGAGGTGATAATGCAACCAGCCCAAGCTCCAGATGCGGTTAAGAGTGCTTTTGATGATGTCATTAAA
GCGCGTGAAGATCGTGAGAGAGAGCAAAACGAAGCTGAAGCATACGCAAATAGAGTAGTACCAGTAGCACAAGGTAACGC
TCAAAGAATATTGGATCAAGCTAATGCTTATAAGCAAAAAATTGTTCTAGAAGCTCAAGGGGAAGTTGCTCAATTTGAAC
AACTGTTACCGATATATAAACAGTCTCCGGATATTGTGATGAATCAAATGTACTTTAATACTATCTCAAATGTGCTACAG
CATAATAAGATATTCTTGATAGATGGTGATGGTGCTAAGAATATTTTCTACGGTTTAAGTGATACACAAAAACAAGCACT
ATTATCAAATACGCAAGGAGGAAATTAA

Upstream 100 bases:

>100_bases
TAATTATTTACCAATAGTCCAAAAAATATAGAATTTTTTATATATAATAGTTAATGCTTGAGTTAAAAATACTTTATAAA
GTCTATAGGAATGATAATTT

Downstream 100 bases:

>100_bases
GATGAGTAAATTCCTAAAAATATTCTTAGTGCTTGTAGTAGTCTTAGCTATAGTAGTATTAAGCACAAAATTTATTGTCA
AACAAGGCTCAGAAGCAGTT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPPIAKIVTIIVALLIVAWVGFG
FYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKENVQELKTIPLKRDMLTSEENIVHISFTVQYRIADLEKYLFA
NTNPTLLLQQALESAVRQVVGENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYKQSPDIVMNQMYFNTISNVLQ
HNKIFLIDGDGAKNIFYGLSDTQKQALLSNTQGGN

Sequences:

>Translated_355_residues
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPPIAKIVTIIVALLIVAWVGFG
FYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKENVQELKTIPLKRDMLTSEENIVHISFTVQYRIADLEKYLFA
NTNPTLLLQQALESAVRQVVGENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYKQSPDIVMNQMYFNTISNVLQ
HNKIFLIDGDGAKNIFYGLSDTQKQALLSNTQGGN
>Mature_355_residues
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPPIAKIVTIIVALLIVAWVGFG
FYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKENVQELKTIPLKRDMLTSEENIVHISFTVQYRIADLEKYLFA
NTNPTLLLQQALESAVRQVVGENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYKQSPDIVMNQMYFNTISNVLQ
HNKIFLIDGDGAKNIFYGLSDTQKQALLSNTQGGN

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=253, Percent_Identity=45.4545454545455, Blast_Score=233, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 40402; Mature: 40402

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPP
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCC
IAKIVTIIVALLIVAWVGFGFYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKEN
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VQELKTIPLKRDMLTSEENIVHISFTVQYRIADLEKYLFANTNPTLLLQQALESAVRQVV
HHHHHHCCCHHHHCCCCCCEEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYK
HHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
QSPDIVMNQMYFNTISNVLQHNKIFLIDGDGAKNIFYGLSDTQKQALLSNTQGGN
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPP
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCC
IAKIVTIIVALLIVAWVGFGFYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKEN
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VQELKTIPLKRDMLTSEENIVHISFTVQYRIADLEKYLFANTNPTLLLQQALESAVRQVV
HHHHHHCCCHHHHCCCCCCEEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYK
HHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
QSPDIVMNQMYFNTISNVLQHNKIFLIDGDGAKNIFYGLSDTQKQALLSNTQGGN
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]