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The map label for this gene is hflX [H]

Identifier: 134302062

GI number: 134302062

Start: 1038548

End: 1039855

Strand: Reverse

Name: hflX [H]

Synonym: FTW_1098

Alternate gene names: 134302062

Gene position: 1039855-1038548 (Counterclockwise)

Preceding gene: 134302063

Following gene: 134302060

Centisome position: 54.77

GC content: 33.41

Gene sequence:

>1308_bases
ATGGAATTTTTCCAATCGTATCAAGCAGGTAGTAAGTGTCTGCTTGTAAATATAAATTTCAAATATCATCGTGAACTTAA
TGCTGATTTAACAGAGTTGGAAGGCTTAGTTATAGCAGCAGAAAAAGTTGTATTGCAAAGTTTAGACTTTAACCATCCTG
AGCCAGATATCAAATACTTTTGCGGTATGGGTAAAATCGAAATGATTAAAAATAAACGCGATGAACTAGAAGCAGATTTA
GTTGTTTTTAACCACCCTTTAACTCCCTCTCAAGAACGTAATATTGAGAAATTTCTTGAGTGCAGAGTTATGGATAGAAC
TAGATTAATTCTAGAGATATTTTCATTACGTGCTAAAACTTATGAGGGTAAACTTCAGGTTGAGTTAGCACAGCTTAACT
ATCAATCAACACGTTTAGTTAAAGGATGGATTCACTTAGAGCGACAAAAGGGTGGTATTGGTGTACGTGGTGGACCTGGT
GAGACACAGCTTGAGATAGACAGACGTTTAATTAGACAGAGGATTAAGCAGATTGCACAAAAGCTTGAGAAAGTAAAACA
TCATCGTGATTTAAGTAGATCTTCGCGTAAAAAAAATAACATTCCAACTATTTCATTTGTGGGATATACGAATGCAGGTA
AATCAACTTTATTTAATAAAATCACAAATGCTGATGTTTTAGCTAAAGATCAGTTGTTTGCGACTTTAGATCCTACTTTG
CGTAAAGTAATCGTACCTAAACTCGGTGAGGTTATATTCTCAGATACTGTAGGCTTTATCAAAAATTTACCACATAATTT
AGTTGAAGCTTTTCATGCTACTTTAGAAGAGGCTATAGAGTCTGATCTTTTGGTACATGTTATAGATTATGCTGACGAGG
ATCATAAAAGCTACATTGAGCAGGTTGAAAAAGTACTCAGTGAAATTGGTATAGCAGACAAAGAGACGATTTGTGTCTAT
AACAAAATTGATAAATTAGAAAATATCAAGCCAAGTTTCGTGCCTCTTGAGGATTCTGATAGTAGCGTAGTTAGTAGGGT
ATATTTATCTGCACAAAATGGAGATGGTTTAGTAGAGTTTTATCAAGCATTAGCTACATTTTTTAATAAAACATGGATAA
ATCAAACTCTATACTTACCGCCTAAATACTCAAAAGTCAGAGCTAAGATGTATGAGCTTGGTGTTATTGATAAAGAAGAG
ATTTCAGAACACGGTAACTATCTATTACAAATAAAAATATCACAAGATGATTTCGAGAGATTTAAAAGGGAACTTAATTT
AGATTTAGAAGAGTTCTTCGTTAAATAA

Upstream 100 bases:

>100_bases
TTCTGATGATCTTGAAATTCAAGAGAATGAAGGTAATATTCACGAGTAATATATCTTTTCTTTTTTCTTTAATAGTTCCA
TTGTGGAGTAATATTAGTTG

Downstream 100 bases:

>100_bases
TTGTTTAAGGTTATTCATACTCTGGAATTTGAATTGGATCATTAAATATCCCAGCACCGATAAATTTAGAAATAACAGGA
GTCGAAGATATCTTAACAGT

Product: protease, GTP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MEFFQSYQAGSKCLLVNINFKYHRELNADLTELEGLVIAAEKVVLQSLDFNHPEPDIKYFCGMGKIEMIKNKRDELEADL
VVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKTYEGKLQVELAQLNYQSTRLVKGWIHLERQKGGIGVRGGPG
ETQLEIDRRLIRQRIKQIAQKLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
RKVIVPKLGEVIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIEQVEKVLSEIGIADKETICVY
NKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEFYQALATFFNKTWINQTLYLPPKYSKVRAKMYELGVIDKEE
ISEHGNYLLQIKISQDDFERFKRELNLDLEEFFVK

Sequences:

>Translated_435_residues
MEFFQSYQAGSKCLLVNINFKYHRELNADLTELEGLVIAAEKVVLQSLDFNHPEPDIKYFCGMGKIEMIKNKRDELEADL
VVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKTYEGKLQVELAQLNYQSTRLVKGWIHLERQKGGIGVRGGPG
ETQLEIDRRLIRQRIKQIAQKLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
RKVIVPKLGEVIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIEQVEKVLSEIGIADKETICVY
NKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEFYQALATFFNKTWINQTLYLPPKYSKVRAKMYELGVIDKEE
ISEHGNYLLQIKISQDDFERFKRELNLDLEEFFVK
>Mature_435_residues
MEFFQSYQAGSKCLLVNINFKYHRELNADLTELEGLVIAAEKVVLQSLDFNHPEPDIKYFCGMGKIEMIKNKRDELEADL
VVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKTYEGKLQVELAQLNYQSTRLVKGWIHLERQKGGIGVRGGPG
ETQLEIDRRLIRQRIKQIAQKLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
RKVIVPKLGEVIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIEQVEKVLSEIGIADKETICVY
NKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEFYQALATFFNKTWINQTLYLPPKYSKVRAKMYELGVIDKEE
ISEHGNYLLQIKISQDDFERFKRELNLDLEEFFVK

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=362, Percent_Identity=29.5580110497238, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI310124269, Length=277, Percent_Identity=32.129963898917, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI310124267, Length=277, Percent_Identity=32.129963898917, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI310124171, Length=277, Percent_Identity=32.129963898917, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI310124169, Length=277, Percent_Identity=32.129963898917, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI310133116, Length=292, Percent_Identity=32.1917808219178, Blast_Score=127, Evalue=3e-29,
Organism=Escherichia coli, GI1790615, Length=422, Percent_Identity=49.5260663507109, Blast_Score=404, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17561038, Length=374, Percent_Identity=29.144385026738, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24650079, Length=407, Percent_Identity=29.97542997543, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50162; Mature: 50162

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFFQSYQAGSKCLLVNINFKYHRELNADLTELEGLVIAAEKVVLQSLDFNHPEPDIKYF
CCHHHHHCCCCEEEEEEECEEEECCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHH
CGMGKIEMIKNKRDELEADLVVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKT
CCCCHHHHHHCCHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
YEGKLQVELAQLNYQSTRLVKGWIHLERQKGGIGVRGGPGETQLEIDRRLIRQRIKQIAQ
CCCEEEEEEECCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEHHHHHHHCCHHH
RKVIVPKLGEVIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHHHHH
QVEKVLSEIGIADKETICVYNKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEF
HHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCCEEECCCCCHHHHHHHEEECCCCCCHHHH
YQALATFFNKTWINQTLYLPPKYSKVRAKMYELGVIDKEEISEHGNYLLQIKISQDDFER
HHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEECHHHHHH
FKRELNLDLEEFFVK
HHHHHCCCHHHHHCC
>Mature Secondary Structure
MEFFQSYQAGSKCLLVNINFKYHRELNADLTELEGLVIAAEKVVLQSLDFNHPEPDIKYF
CCHHHHHCCCCEEEEEEECEEEECCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHH
CGMGKIEMIKNKRDELEADLVVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKT
CCCCHHHHHHCCHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
YEGKLQVELAQLNYQSTRLVKGWIHLERQKGGIGVRGGPGETQLEIDRRLIRQRIKQIAQ
CCCEEEEEEECCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEHHHHHHHCCHHH
RKVIVPKLGEVIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHHHHH
QVEKVLSEIGIADKETICVYNKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEF
HHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCCEEECCCCCHHHHHHHEEECCCCCCHHHH
YQALATFFNKTWINQTLYLPPKYSKVRAKMYELGVIDKEEISEHGNYLLQIKISQDDFER
HHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEECHHHHHH
FKRELNLDLEEFFVK
HHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]