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The map label for this gene is grxB [H]

Identifier: 134302045

GI number: 134302045

Start: 1019256

End: 1019900

Strand: Direct

Name: grxB [H]

Synonym: FTW_1079

Alternate gene names: 134302045

Gene position: 1019256-1019900 (Clockwise)

Preceding gene: 134302034

Following gene: 134302046

Centisome position: 53.69

GC content: 29.92

Gene sequence:

>645_bases
ATGAAAATATATCTATATCACCATTGCCCTTACTGTATAAAAGTAAGACTAGTTGCTGACTTAAGCAATTTCGACTATCA
GATGATAATTCTAGCAAATGATGATGAAAAAGCTCATATCGATAGAATTGGCTCAAAACAAGTACCTTTTTTAGAAAAAG
ATGATGGTACTTTTATCAAAGAAAGTGATGAGATCTGCAAGTTTATTGCCAAGGTTCAGAATTTTGAAATTGCAGAATCA
ACTATTGATGATTTCGTCAAAGGCTGTATTGCCGATCTAGAGCCACATTATCGTAGAATTATATATCCTCGAATTCCTCA
TCATCCACGTAATGAATGTGACTTTCCAACGCAAAGTGCTAAAGAATATTTTATAAATAAAAAATCTCAATATATTGGTG
ATTTCGATGCTTTACTTAGAAATCCTCCATATGACTCAATTAGAGCAATAAACCAAATACTTGCAAAAATTGATCCTTTT
ATTAAAACTCCTTTTATCAATGGTGAAAAGTTTTCTTGGGATGATATAAATATTTTTCCAATATTTTTTATCCTAACAAT
GTCTAAGGATTTGCTTGAAATACCAACAAATATTACCAACTATATCAAAAATATCGAAGCAAAAACAAACATAGAATTGT
ACTAA

Upstream 100 bases:

>100_bases
TTTTGTACTTTTTAACACAATAGTTGATTGCTTAAACAAGTTTATCTAATCTCAAGAAATGATATAATTAACGCAATAAT
TAATGAATATGTGAAATATT

Downstream 100 bases:

>100_bases
AATGATTATATCTATAGAAGCAATTGATAAAGTATTACCACAAACACAATGTCAAAAGTGTACTTATCCTGATTGTTATA
GCTATGCTAAAGCTATAACA

Product: glutaredoxin 2

Products: NA

Alternate protein names: Grx2 [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKIYLYHHCPYCIKVRLVADLSNFDYQMIILANDDEKAHIDRIGSKQVPFLEKDDGTFIKESDEICKFIAKVQNFEIAES
TIDDFVKGCIADLEPHYRRIIYPRIPHHPRNECDFPTQSAKEYFINKKSQYIGDFDALLRNPPYDSIRAINQILAKIDPF
IKTPFINGEKFSWDDINIFPIFFILTMSKDLLEIPTNITNYIKNIEAKTNIELY

Sequences:

>Translated_214_residues
MKIYLYHHCPYCIKVRLVADLSNFDYQMIILANDDEKAHIDRIGSKQVPFLEKDDGTFIKESDEICKFIAKVQNFEIAES
TIDDFVKGCIADLEPHYRRIIYPRIPHHPRNECDFPTQSAKEYFINKKSQYIGDFDALLRNPPYDSIRAINQILAKIDPF
IKTPFINGEKFSWDDINIFPIFFILTMSKDLLEIPTNITNYIKNIEAKTNIELY
>Mature_214_residues
MKIYLYHHCPYCIKVRLVADLSNFDYQMIILANDDEKAHIDRIGSKQVPFLEKDDGTFIKESDEICKFIAKVQNFEIAES
TIDDFVKGCIADLEPHYRRIIYPRIPHHPRNECDFPTQSAKEYFINKKSQYIGDFDALLRNPPYDSIRAINQILAKIDPF
IKTPFINGEKFSWDDINIFPIFFILTMSKDLLEIPTNITNYIKNIEAKTNIELY

Specific function: Involved in reducing some disulfides in a coupled system with glutathione reductase. Does not act as hydrogen donor for ribonucleotide reductase [H]

COG id: COG2999

COG function: function code O; Glutaredoxin 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787303, Length=220, Percent_Identity=30, Blast_Score=114, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR007494
- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR011901
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF04399 Glutaredoxin2_C [H]

EC number: NA

Molecular weight: Translated: 25123; Mature: 25123

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00092 N6_MTASE ; PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYLYHHCPYCIKVRLVADLSNFDYQMIILANDDEKAHIDRIGSKQVPFLEKDDGTFIK
CEEEEEECCCEEEEEEEEEECCCCCEEEEEEECCCCHHHHHHCCCCCCCEEECCCCCEEE
ESDEICKFIAKVQNFEIAESTIDDFVKGCIADLEPHYRRIIYPRIPHHPRNECDFPTQSA
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCHHH
KEYFINKKSQYIGDFDALLRNPPYDSIRAINQILAKIDPFIKTPFINGEKFSWDDINIFP
HHHHHCCHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCHHH
IFFILTMSKDLLEIPTNITNYIKNIEAKTNIELY
HHHHHHHCHHHHHCCHHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure
MKIYLYHHCPYCIKVRLVADLSNFDYQMIILANDDEKAHIDRIGSKQVPFLEKDDGTFIK
CEEEEEECCCEEEEEEEEEECCCCCEEEEEEECCCCHHHHHHCCCCCCCEEECCCCCEEE
ESDEICKFIAKVQNFEIAESTIDDFVKGCIADLEPHYRRIIYPRIPHHPRNECDFPTQSA
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCHHH
KEYFINKKSQYIGDFDALLRNPPYDSIRAINQILAKIDPFIKTPFINGEKFSWDDINIFP
HHHHHCCHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCHHH
IFFILTMSKDLLEIPTNITNYIKNIEAKTNIELY
HHHHHHHCHHHHHCCHHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]