| Definition | Francisella tularensis subsp. tularensis WY96-3418, complete genome. |
|---|---|
| Accession | NC_009257 |
| Length | 1,898,476 |
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The map label for this gene is sufC [H]
Identifier: 134301879
GI number: 134301879
Start: 845121
End: 845870
Strand: Direct
Name: sufC [H]
Synonym: FTW_0874
Alternate gene names: 134301879
Gene position: 845121-845870 (Clockwise)
Preceding gene: 134301878
Following gene: 134301880
Centisome position: 44.52
GC content: 33.07
Gene sequence:
>750_bases ATGTTGTTAGAAATTAAAGATTTACATGTAAGTGTTGGTGAACAAAAAAAACAAATACTAAAAGGATTAAACTTAACAGT TAAAAAAGGTGAAGTCCATGCAATTATGGGACCAAATGGAGCTGGCAAAAGTACTTTAAGTAATGTTTTAGCTGGTAAAG ATGGTTATGAAATTACTCAAGGTTCAATCACATTTGATGGTAAAGATTTAAATGATTTAAGTATCTCAGAAAGAGCTGCA GCCGGCATATTTTTAAGCTTACAGTATCCAATTGAAATCCCTGGAGTTAGTAATGTGCAGTTCCTTAAAACCGCTTTAAA TAGTATTAGAAAGCAAAATGGTGAAGATGAAATTGATGCAATTTCTTTTATGAAAAAACTAAAAGAGAATATGCAGGTAT TAAAAATTGATCAAAAATATATGTCACGAGGAGTTAATGAAGGCTTCTCAGGTGGTGAGAAAAAACGTAATGAAATGCTG CAACTTATGATGCTTGAGCCAAAATTAGCTATACTAGATGAAACTGATTCTGGTCTAGACATAGATGCTCTACAAGTAGT ATCACAAGGGGCAAACAGTATGAGATCAGCAGACAGAAGCTTTTTAGTAATCACTCACTACCAAAGACTTCTAGATCATA TTCAACCAGATTTTGTCCATGTTTTAGCAGATGGTAAAATAGTTAAGACTGGTGGAAAAGAGCTTGCTCTTGAATTAGAA GAGAAAGGTTATTCTTGGTTAAACAGCTAA
Upstream 100 bases:
>100_bases TTGAGTTTGCTGTTGAAGCTCAGAAGCTTATGGAAGTCAGTCTAGAAGGTGCAGTTGGTTAAGCTATAAATTATATAATT TGATAAAAAAGGTTTAAAAA
Downstream 100 bases:
>100_bases AGGTTGCTAAAAATGTTAATAGATAATAAATCTCTGCCTACTACTAAACAAGAAAGCTGGAAGTATACAAATATTGCTTC TATTTATGAGAAGAATAATA
Product: FeS assembly ATPase SufC
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 249; Mature: 249
Protein sequence:
>249_residues MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQGSITFDGKDLNDLSISERAA AGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDAISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEML QLMMLEPKLAILDETDSGLDIDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKTGGKELALELE EKGYSWLNS
Sequences:
>Translated_249_residues MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQGSITFDGKDLNDLSISERAA AGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDAISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEML QLMMLEPKLAILDETDSGLDIDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKTGGKELALELE EKGYSWLNS >Mature_249_residues MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQGSITFDGKDLNDLSISERAA AGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDAISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEML QLMMLEPKLAILDETDSGLDIDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKTGGKELALELE EKGYSWLNS
Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f
COG id: COG0396
COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI9955963, Length=240, Percent_Identity=27.9166666666667, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI42741659, Length=243, Percent_Identity=30.0411522633745, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI4505771, Length=240, Percent_Identity=30.8333333333333, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI9961250, Length=240, Percent_Identity=30.8333333333333, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI9961252, Length=240, Percent_Identity=30.8333333333333, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI156105685, Length=230, Percent_Identity=31.304347826087, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI148612844, Length=222, Percent_Identity=31.5315315315315, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI255708477, Length=222, Percent_Identity=31.5315315315315, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI21536378, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI73747915, Length=224, Percent_Identity=29.0178571428571, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1787972, Length=247, Percent_Identity=57.8947368421053, Blast_Score=303, Evalue=7e-84, Organism=Escherichia coli, GI1788761, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1790525, Length=215, Percent_Identity=30.6976744186047, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1789672, Length=191, Percent_Identity=25.6544502617801, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1787029, Length=209, Percent_Identity=24.8803827751196, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789891, Length=224, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786319, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1786253, Length=210, Percent_Identity=30, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI87081709, Length=217, Percent_Identity=25.3456221198157, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1788897, Length=212, Percent_Identity=26.8867924528302, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787500, Length=247, Percent_Identity=27.9352226720648, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI193202349, Length=236, Percent_Identity=30.0847457627119, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI193211017, Length=225, Percent_Identity=32, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193211015, Length=225, Percent_Identity=32, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI71996809, Length=225, Percent_Identity=32, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17533971, Length=218, Percent_Identity=27.9816513761468, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI115533592, Length=229, Percent_Identity=27.5109170305677, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI212646699, Length=240, Percent_Identity=27.5, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI25146777, Length=236, Percent_Identity=29.6610169491525, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17541710, Length=232, Percent_Identity=26.7241379310345, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI115535101, Length=242, Percent_Identity=29.7520661157025, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193209708, Length=233, Percent_Identity=27.4678111587983, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71992285, Length=224, Percent_Identity=28.125, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI71992290, Length=248, Percent_Identity=25.4032258064516, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17558664, Length=222, Percent_Identity=29.2792792792793, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17567265, Length=238, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17567269, Length=246, Percent_Identity=28.8617886178862, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17565938, Length=222, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17569145, Length=247, Percent_Identity=24.6963562753036, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6323217, Length=227, Percent_Identity=29.9559471365639, Blast_Score=77, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6324985, Length=248, Percent_Identity=29.4354838709677, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI281363262, Length=219, Percent_Identity=32.8767123287671, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24653245, Length=219, Percent_Identity=32.8767123287671, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI85726357, Length=241, Percent_Identity=27.3858921161826, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI85816269, Length=244, Percent_Identity=30.327868852459, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24580553, Length=244, Percent_Identity=30.327868852459, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI85724864, Length=244, Percent_Identity=30.327868852459, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24580555, Length=244, Percent_Identity=30.327868852459, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI17136662, Length=218, Percent_Identity=28.8990825688073, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24641565, Length=218, Percent_Identity=27.9816513761468, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI28574744, Length=228, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI161076684, Length=252, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24581617, Length=252, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24581615, Length=252, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI161076682, Length=252, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010230 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 27447; Mature: 27447
Theoretical pI: Translated: 6.05; Mature: 6.05
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQ CEEEEEHHHCCCCHHHHHHHHCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCEEEC GSITFDGKDLNDLSISERAAAGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDA CEEEECCCCCCCCCHHHHHHCEEEEEEECCEECCCCCCHHHHHHHHHHHHHCCCCCHHHH ISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEMLQLMMLEPKLAILDETDSGLD HHHHHHHHHCHHEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCC IDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKTGGKELALELE HHHHHHHHHCHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEEEH EKGYSWLNS HCCCCCCCC >Mature Secondary Structure MLLEIKDLHVSVGEQKKQILKGLNLTVKKGEVHAIMGPNGAGKSTLSNVLAGKDGYEITQ CEEEEEHHHCCCCHHHHHHHHCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCEEEC GSITFDGKDLNDLSISERAAAGIFLSLQYPIEIPGVSNVQFLKTALNSIRKQNGEDEIDA CEEEECCCCCCCCCHHHHHHCEEEEEEECCEECCCCCCHHHHHHHHHHHHHCCCCCHHHH ISFMKKLKENMQVLKIDQKYMSRGVNEGFSGGEKKRNEMLQLMMLEPKLAILDETDSGLD HHHHHHHHHCHHEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCC IDALQVVSQGANSMRSADRSFLVITHYQRLLDHIQPDFVHVLADGKIVKTGGKELALELE HHHHHHHHHCHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEEEH EKGYSWLNS HCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9097039; 9278503; 10322040 [H]