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The map label for this gene is engA [H]

Identifier: 134301774

GI number: 134301774

Start: 717239

End: 718636

Strand: Direct

Name: engA [H]

Synonym: FTW_0740

Alternate gene names: 134301774

Gene position: 717239-718636 (Clockwise)

Preceding gene: 134301773

Following gene: 134301775

Centisome position: 37.78

GC content: 35.55

Gene sequence:

>1398_bases
ATGTCTTTTTTAGTTGCAATTGTAGGTAGAGCCAATGTTGGTAAATCTACTCTTTTTAATGTTTTGACAAATTCGCACGA
TGCCTTAGTATTTGATTTTGAGGGTGTAACTCGTGATCGTCAATACGGACAAGCAAAGTATGATGATTTAGATTATCTAG
TAGTTGATACTGGAGGTATTTCAGATAAAGATGTGGGTTTTGATGAGTTTATGGCTAAACAATCACAGATTGCTATAGAT
GAGGCGAATTTAGTTTTCTTTGTGGTTGATGGCAGATCTGGATTGACAACCGGAGATGAGTACGTTGCTAGCCTTTTACG
CCAGAAAGATAAGAAAGTAGTAGTTGTGGTAAATAAGGTTGATGGTACTGATGAAGAAGCTGCAATGGCTGAATTTTATA
GTTTTGGTTTTGATAAGGTATTTGCAATATCTGCAGCACATCGTAGAAACACGCAAAAGCTAGTTGATAAGTTTCTAAAA
AAACCATTAAATGAATACTATCAAGATTATACTCAAACACAAGAGCATAAAGAACAACAGCGCCATGGTATCCATTTTTC
ATTAATTGGTAGACCTAACGTTGGTAAATCGACACTTACAAATAGAATGCTTGGCGAAGATAGGGTTGTGGTATTTGACA
TGCCAGGCACTACAATTGATAGTGTCAGTATCCCATTTGAACGCCATGGTCAGAAGTATACTATAGTTGATACAGCTGGT
GTGCGCAAAAGAGGTAAGGTAAAACAAACTTTGGAAAAGTTTTCGGTAATAAAAACATTACAAGCAATACAAGATTCAAA
TGTAGTAGTTGCAGTAGTTGATGCAAGACAAGGTATCTCAGATCAAGACCTGAGTCTGATACATTTTGCTATTAAAAATG
GTAGAGCATTGGTCTTAGCTGTAAATAAATGGGATGGTATGACAGAAGAAGATCGTATTCAGGTTAAGCAAGATCTTAAA
AGAAAGCTTTTTTTCCTGCAAGATTATGTCGATATACATTTTATCTCAGCATTACATGGTACTAATGTTGGGCATGTTTT
TGAGTCAATTGATACTGCATATGCATGTGCAAATAAAAAAATAACTACAGCTGATGCTACACGTCTAATGCAGCTTGCGG
TAGAGGCACACTCACCGCCAATGGTAGGTAAATTTAGAATTAAGCTTAAGTACGCTCATGTTGGAGGACATAATCCTCCT
GTTATTGTAATACATGGTAATCAAGTAAGTAGACTGCCAAACTCATATAAAAGATATTTAGAAAATTTCTTTAGAGAAGC
CTTAGATTTTCGTGGTACGCCAATAGTATTTGAGTTTAAGCAGTCAGAAAACCCTTTTGCAGATAGAAAAAATAAGAGAT
CAAAAGATGAAGGCAGTAAGAGTAAAAAAGTTAAGTAA

Upstream 100 bases:

>100_bases
TTACAAATTAATTTTTACTTTAAGTGATTTGCTTTATAAAAATTCTGAAATAGAGTAAGATTATCGATAAATATATAAAT
TATAAAATTATTGAGTAAAG

Downstream 100 bases:

>100_bases
GCTTGCTGATGAGATAACTATTAACATTAGTGGTGCAAAAAATGCTTTGTTACATCTAATTTTTGCAAGCTTAATTCCGG
ATACTAAAACAAAATTTACT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSFLVAIVGRANVGKSTLFNVLTNSHDALVFDFEGVTRDRQYGQAKYDDLDYLVVDTGGISDKDVGFDEFMAKQSQIAID
EANLVFFVVDGRSGLTTGDEYVASLLRQKDKKVVVVVNKVDGTDEEAAMAEFYSFGFDKVFAISAAHRRNTQKLVDKFLK
KPLNEYYQDYTQTQEHKEQQRHGIHFSLIGRPNVGKSTLTNRMLGEDRVVVFDMPGTTIDSVSIPFERHGQKYTIVDTAG
VRKRGKVKQTLEKFSVIKTLQAIQDSNVVVAVVDARQGISDQDLSLIHFAIKNGRALVLAVNKWDGMTEEDRIQVKQDLK
RKLFFLQDYVDIHFISALHGTNVGHVFESIDTAYACANKKITTADATRLMQLAVEAHSPPMVGKFRIKLKYAHVGGHNPP
VIVIHGNQVSRLPNSYKRYLENFFREALDFRGTPIVFEFKQSENPFADRKNKRSKDEGSKSKKVK

Sequences:

>Translated_465_residues
MSFLVAIVGRANVGKSTLFNVLTNSHDALVFDFEGVTRDRQYGQAKYDDLDYLVVDTGGISDKDVGFDEFMAKQSQIAID
EANLVFFVVDGRSGLTTGDEYVASLLRQKDKKVVVVVNKVDGTDEEAAMAEFYSFGFDKVFAISAAHRRNTQKLVDKFLK
KPLNEYYQDYTQTQEHKEQQRHGIHFSLIGRPNVGKSTLTNRMLGEDRVVVFDMPGTTIDSVSIPFERHGQKYTIVDTAG
VRKRGKVKQTLEKFSVIKTLQAIQDSNVVVAVVDARQGISDQDLSLIHFAIKNGRALVLAVNKWDGMTEEDRIQVKQDLK
RKLFFLQDYVDIHFISALHGTNVGHVFESIDTAYACANKKITTADATRLMQLAVEAHSPPMVGKFRIKLKYAHVGGHNPP
VIVIHGNQVSRLPNSYKRYLENFFREALDFRGTPIVFEFKQSENPFADRKNKRSKDEGSKSKKVK
>Mature_464_residues
SFLVAIVGRANVGKSTLFNVLTNSHDALVFDFEGVTRDRQYGQAKYDDLDYLVVDTGGISDKDVGFDEFMAKQSQIAIDE
ANLVFFVVDGRSGLTTGDEYVASLLRQKDKKVVVVVNKVDGTDEEAAMAEFYSFGFDKVFAISAAHRRNTQKLVDKFLKK
PLNEYYQDYTQTQEHKEQQRHGIHFSLIGRPNVGKSTLTNRMLGEDRVVVFDMPGTTIDSVSIPFERHGQKYTIVDTAGV
RKRGKVKQTLEKFSVIKTLQAIQDSNVVVAVVDARQGISDQDLSLIHFAIKNGRALVLAVNKWDGMTEEDRIQVKQDLKR
KLFFLQDYVDIHFISALHGTNVGHVFESIDTAYACANKKITTADATRLMQLAVEAHSPPMVGKFRIKLKYAHVGGHNPPV
IVIHGNQVSRLPNSYKRYLENFFREALDFRGTPIVFEFKQSENPFADRKNKRSKDEGSKSKKVK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=483, Percent_Identity=49.8964803312629, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI1788919, Length=247, Percent_Identity=28.3400809716599, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=161, Percent_Identity=31.055900621118, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=158, Percent_Identity=29.746835443038, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52443; Mature: 52312

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLVAIVGRANVGKSTLFNVLTNSHDALVFDFEGVTRDRQYGQAKYDDLDYLVVDTGGI
CCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHCCCCCCCCCCEEEEECCCC
SDKDVGFDEFMAKQSQIAIDEANLVFFVVDGRSGLTTGDEYVASLLRQKDKKVVVVVNKV
CCCCCCHHHHHHCCHHEEEECCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECC
DGTDEEAAMAEFYSFGFDKVFAISAAHRRNTQKLVDKFLKKPLNEYYQDYTQTQEHKEQQ
CCCCHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHGIHFSLIGRPNVGKSTLTNRMLGEDRVVVFDMPGTTIDSVSIPFERHGQKYTIVDTAG
HCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEECCHHHCCCEEEEEECCC
VRKRGKVKQTLEKFSVIKTLQAIQDSNVVVAVVDARQGISDQDLSLIHFAIKNGRALVLA
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEE
VNKWDGMTEEDRIQVKQDLKRKLFFLQDYVDIHFISALHGTNVGHVFESIDTAYACANKK
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCHHHHHHHHHHHHHHCCCE
ITTADATRLMQLAVEAHSPPMVGKFRIKLKYAHVGGHNPPVIVIHGNQVSRLPNSYKRYL
EEHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCEEEEECCHHHHCHHHHHHHH
ENFFREALDFRGTPIVFEFKQSENPFADRKNKRSKDEGSKSKKVK
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFLVAIVGRANVGKSTLFNVLTNSHDALVFDFEGVTRDRQYGQAKYDDLDYLVVDTGGI
CEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHCCCCCCCCCCEEEEECCCC
SDKDVGFDEFMAKQSQIAIDEANLVFFVVDGRSGLTTGDEYVASLLRQKDKKVVVVVNKV
CCCCCCHHHHHHCCHHEEEECCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECC
DGTDEEAAMAEFYSFGFDKVFAISAAHRRNTQKLVDKFLKKPLNEYYQDYTQTQEHKEQQ
CCCCHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHGIHFSLIGRPNVGKSTLTNRMLGEDRVVVFDMPGTTIDSVSIPFERHGQKYTIVDTAG
HCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEECCHHHCCCEEEEEECCC
VRKRGKVKQTLEKFSVIKTLQAIQDSNVVVAVVDARQGISDQDLSLIHFAIKNGRALVLA
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEE
VNKWDGMTEEDRIQVKQDLKRKLFFLQDYVDIHFISALHGTNVGHVFESIDTAYACANKK
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCHHHHHHHHHHHHHHCCCE
ITTADATRLMQLAVEAHSPPMVGKFRIKLKYAHVGGHNPPVIVIHGNQVSRLPNSYKRYL
EEHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCEEEEECCHHHHCHHHHHHHH
ENFFREALDFRGTPIVFEFKQSENPFADRKNKRSKDEGSKSKKVK
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA