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The map label for this gene is murA [H]

Identifier: 134301775

GI number: 134301775

Start: 718605

End: 719909

Strand: Direct

Name: murA [H]

Synonym: FTW_0741

Alternate gene names: 134301775

Gene position: 718605-719909 (Clockwise)

Preceding gene: 134301774

Following gene: 134301776

Centisome position: 37.85

GC content: 32.26

Gene sequence:

>1305_bases
ATGAAGGCAGTAAGAGTAAAAAAGTTAAGTAAGCTTGCTGATGAGATAACTATTAACATTAGTGGTGCAAAAAATGCTTT
GTTACATCTAATTTTTGCAAGCTTAATTCCGGATACTAAAACAAAATTTACTAATGTTCCAACAACTCTTTTAGATTATA
AAGGGGCTAAGGAGATCTTAGAAAATGTTGGTGCTAAAGTCATTGAAAAGGATGAAGAAGTAACTATTGATACTGCAGCT
ATTTCAAATGAAACTTTAGAACTATGTGGGGAAATGACATCTAAAACACGTTGCTCTTTGATGCTTTTAGGTTCATTGCT
TAAGAAAAAAGGTCGTGTTAAGATTGGTTTTCCTGGTGGTTGTAGTTTTAGTGAAAAAAGACCTTTTGACATACACTTAA
ATGGATTAGAAGCATTAGGTGCTGAGGTTAAGTTGGCTGATGATCATATAGAGGTAATTTATAAAGAAGAAAAAAACGCA
GAGTTTAAAATGCCTTTTCCATCGGTTGGCGCAACTATGAATTTACTAATGTACGCCGTGACAGGTAATTCTGAGGTTGT
ACTTGAAAATGTTGCTTTAGAGCCTGAGGTTGTTACATTAATAGACTATCTTAATCAATGTGGTGCAAATATTGATTTTG
ATGCTGATAGCAGAAAAATAAAAATCTTAGGTGTTATGAGATTAAATGGCTGTGAGTTTGAAATTATTTTTGACCGTATT
CAAGCTATGACCTATGCCGCTATGGCGTATCTGTACAAAACAAACGTTACAATTACAAATATTAATACTCAAGATACATA
CAGTATCAAAAAGCCTTTGGAAAAATTGACTAATGCAGGAGCTAAATGGGAGTATAACCAAGCTAATCGTAGTATTAAGT
TTTTTGGTAAGGATAGTTGTATTAAAGGAGTTGATATAATTGCTGCACCTTTCCCACATTTTCCTACCGATTTACAGCCA
ATATATGCAGTAATGTTATTTATGGCAAATAGCTCTAGTACTATTCAAGATACAGTTTACCCTGAGCGCATAAATTATGT
GTATCAAATTCGTAAAATGGGTTTTAATATATCTATAGATAATACTCTTATAAAAATAAATCCACTTAAAAACCTAAATG
ATATACGTCCAGCAGTGATGAGTGTCAAAGATTTACGTGCTGGTATGGCATGCTTAATGGCTGGATCATTATTAGATGAA
TTTTCGACTATTAATAATGCTCATCAGATATTTAGAGGTTATAATAACCTTATAGAAAATATGTCTCATTTTATGCGAAT
AGAGATTCTAAATGATAATGTTTAG

Upstream 100 bases:

>100_bases
TTCTTTAGAGAAGCCTTAGATTTTCGTGGTACGCCAATAGTATTTGAGTTTAAGCAGTCAGAAAACCCTTTTGCAGATAG
AAAAAATAAGAGATCAAAAG

Downstream 100 bases:

>100_bases
GTGAATAATGTCAGAGTATATATCTTTAGAGCAATATAATACCTATCGTATTAAGTCTTTTGCTAAATATGTTTATTTTC
CTACTAATAACCAAGAGCTA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKAVRVKKLSKLADEITINISGAKNALLHLIFASLIPDTKTKFTNVPTTLLDYKGAKEILENVGAKVIEKDEEVTIDTAA
ISNETLELCGEMTSKTRCSLMLLGSLLKKKGRVKIGFPGGCSFSEKRPFDIHLNGLEALGAEVKLADDHIEVIYKEEKNA
EFKMPFPSVGATMNLLMYAVTGNSEVVLENVALEPEVVTLIDYLNQCGANIDFDADSRKIKILGVMRLNGCEFEIIFDRI
QAMTYAAMAYLYKTNVTITNINTQDTYSIKKPLEKLTNAGAKWEYNQANRSIKFFGKDSCIKGVDIIAAPFPHFPTDLQP
IYAVMLFMANSSSTIQDTVYPERINYVYQIRKMGFNISIDNTLIKINPLKNLNDIRPAVMSVKDLRAGMACLMAGSLLDE
FSTINNAHQIFRGYNNLIENMSHFMRIEILNDNV

Sequences:

>Translated_434_residues
MKAVRVKKLSKLADEITINISGAKNALLHLIFASLIPDTKTKFTNVPTTLLDYKGAKEILENVGAKVIEKDEEVTIDTAA
ISNETLELCGEMTSKTRCSLMLLGSLLKKKGRVKIGFPGGCSFSEKRPFDIHLNGLEALGAEVKLADDHIEVIYKEEKNA
EFKMPFPSVGATMNLLMYAVTGNSEVVLENVALEPEVVTLIDYLNQCGANIDFDADSRKIKILGVMRLNGCEFEIIFDRI
QAMTYAAMAYLYKTNVTITNINTQDTYSIKKPLEKLTNAGAKWEYNQANRSIKFFGKDSCIKGVDIIAAPFPHFPTDLQP
IYAVMLFMANSSSTIQDTVYPERINYVYQIRKMGFNISIDNTLIKINPLKNLNDIRPAVMSVKDLRAGMACLMAGSLLDE
FSTINNAHQIFRGYNNLIENMSHFMRIEILNDNV
>Mature_434_residues
MKAVRVKKLSKLADEITINISGAKNALLHLIFASLIPDTKTKFTNVPTTLLDYKGAKEILENVGAKVIEKDEEVTIDTAA
ISNETLELCGEMTSKTRCSLMLLGSLLKKKGRVKIGFPGGCSFSEKRPFDIHLNGLEALGAEVKLADDHIEVIYKEEKNA
EFKMPFPSVGATMNLLMYAVTGNSEVVLENVALEPEVVTLIDYLNQCGANIDFDADSRKIKILGVMRLNGCEFEIIFDRI
QAMTYAAMAYLYKTNVTITNINTQDTYSIKKPLEKLTNAGAKWEYNQANRSIKFFGKDSCIKGVDIIAAPFPHFPTDLQP
IYAVMLFMANSSSTIQDTVYPERINYVYQIRKMGFNISIDNTLIKINPLKNLNDIRPAVMSVKDLRAGMACLMAGSLLDE
FSTINNAHQIFRGYNNLIENMSHFMRIEILNDNV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=31.1904761904762, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 48474; Mature: 48474

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVRVKKLSKLADEITINISGAKNALLHLIFASLIPDTKTKFTNVPTTLLDYKGAKEIL
CCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHHH
ENVGAKVIEKDEEVTIDTAAISNETLELCGEMTSKTRCSLMLLGSLLKKKGRVKIGFPGG
HHCCHHHCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
CSFSEKRPFDIHLNGLEALGAEVKLADDHIEVIYKEEKNAEFKMPFPSVGATMNLLMYAV
CCCCCCCCEEEEECCHHHCCCEEEEECCCEEEEEECCCCCEEECCCCCCCCCEEEEEEEE
TGNSEVVLENVALEPEVVTLIDYLNQCGANIDFDADSRKIKILGVMRLNGCEFEIIFDRI
ECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCEEHHHHHH
QAMTYAAMAYLYKTNVTITNINTQDTYSIKKPLEKLTNAGAKWEYNQANRSIKFFGKDSC
HHHHHHHHHHHEECCEEEEECCCCCCHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCC
IKGVDIIAAPFPHFPTDLQPIYAVMLFMANSSSTIQDTVYPERINYVYQIRKMGFNISID
CCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHCCCEEEEC
NTLIKINPLKNLNDIRPAVMSVKDLRAGMACLMAGSLLDEFSTINNAHQIFRGYNNLIEN
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSHFMRIEILNDNV
HHHHEEEEEECCCC
>Mature Secondary Structure
MKAVRVKKLSKLADEITINISGAKNALLHLIFASLIPDTKTKFTNVPTTLLDYKGAKEIL
CCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHHH
ENVGAKVIEKDEEVTIDTAAISNETLELCGEMTSKTRCSLMLLGSLLKKKGRVKIGFPGG
HHCCHHHCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
CSFSEKRPFDIHLNGLEALGAEVKLADDHIEVIYKEEKNAEFKMPFPSVGATMNLLMYAV
CCCCCCCCEEEEECCHHHCCCEEEEECCCEEEEEECCCCCEEECCCCCCCCCEEEEEEEE
TGNSEVVLENVALEPEVVTLIDYLNQCGANIDFDADSRKIKILGVMRLNGCEFEIIFDRI
ECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCEEHHHHHH
QAMTYAAMAYLYKTNVTITNINTQDTYSIKKPLEKLTNAGAKWEYNQANRSIKFFGKDSC
HHHHHHHHHHHEECCEEEEECCCCCCHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCC
IKGVDIIAAPFPHFPTDLQPIYAVMLFMANSSSTIQDTVYPERINYVYQIRKMGFNISID
CCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHCCCEEEEC
NTLIKINPLKNLNDIRPAVMSVKDLRAGMACLMAGSLLDEFSTINNAHQIFRGYNNLIEN
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSHFMRIEILNDNV
HHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA