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The map label for this gene is capB [H]

Identifier: 134301662

GI number: 134301662

Start: 595870

End: 597078

Strand: Direct

Name: capB [H]

Synonym: FTW_0602

Alternate gene names: 134301662

Gene position: 595870-597078 (Clockwise)

Preceding gene: 134301661

Following gene: 134301663

Centisome position: 31.39

GC content: 34.33

Gene sequence:

>1209_bases
TTGGATTTTTGGTTAATTGTCGTCGTATTTGTGATTTTATGCGTTTATCTAATAATAGAAAATATAGTGCATAATAATAG
TATTAAAAGTATTCCTATTAGGATTCATGTCAATGGTACTCGTGGTAAGTCAAGTGTTGCGAGACTTATTGCAGCTGGTG
TTAGAGCTGGAGGATATAGAACAGTAGCTAAGACTACTGGAACTTTAGCAAGATATATTGATGTTGATGGTTCAGAAACA
CCTGTATTTAGAATAGGCTTTAGTAATATTGCTGAGCAAGTTAAGATTATGTTTAAGGCAAGAAGAGCAAAAGCTGATGC
TATCGTTATCGAGTGTATGGCTTTACAGCCACTTTTGCAATCGCTGTGTGAGTTAAAGCTTATTAAAGCGACACATGGAG
TTTTGACAAATGCTCGTCCTGATCATTTAGATGTTATGGGTCCTACAGAAAGAGATGTTGCAAAAGCATTAGCAGCTACT
GTCCCTGTTGGAGCTAAGTATTTTACTGCGGAAGATATCCATTTAGATTTTTTTGAATATGCTTGTAAAGACCGAGGCTC
AGAACTAATCGCAGCTACAGCACAAGATGCTGAGAAAATATCTGATGAAGAAATAAATAAGTTTGTATACTCAGAATTTA
AGATAAATGTTGCTCTAGCATTAAAAGTAACAGATGATTTGGGTATACCTAGAGAAATCGCTATTAAAGGAATGTGGGAA
GCGACCCCAGATCCAGGTGCGATGACGGAGTATAATTTTAATATTAAAAATGCTGAAATAAATTTTGCTAATGCTTTTGC
TGCTAATGATCCTGTATCAACAAAAATGCTTTGGGATAAGCTTTGTGCTAAGTATTCAGGCTGTGATAAGAAAGTATTGG
TTGTTAACTGTAGAGATGATAGAGAGGATCGCTCAAAACAAATGGCAGAAGCAGCTCTAGGTTGGCAAAAACAAGATTTA
ATTGTTCTAATAGGTACTGGTACAGAGGTTTTTACTTCGTTTTATAAAAAATATGCAAAATCACTTAATAAACCAATGAC
TAAAGTCATAGTTTGTGAAGAGATGACACCTATACAAATACTTGAAAAAACAGTTGATTCAAATCCAGCAAACTCTTATA
TTCTTGTTGGAGTTGGTAATATTAAAGATATTGGTATGGAATTAGTTGATTACTGTGATACTAGCCATAAAAAGAAGCAT
AATTTATAG

Upstream 100 bases:

>100_bases
ATTTGTTGATATTTAGATAGATTAAATTCTAATGCCTTTGTATATTATATACACAGTGATATAATCTAGATTGTAATTTA
TTACATAAAAGGTGACTACT

Downstream 100 bases:

>100_bases
TTTTAAGATTAAACAGGAGAAAATATGGATCCGTTAACGCTCTCGATAGGAATTGGTCTTGTAGTTGGTCTAGTTTTTGT
GTCACTATTAGGACTATCTA

Product: capsule biosynthesis protein capB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MDFWLIVVVFVILCVYLIIENIVHNNSIKSIPIRIHVNGTRGKSSVARLIAAGVRAGGYRTVAKTTGTLARYIDVDGSET
PVFRIGFSNIAEQVKIMFKARRAKADAIVIECMALQPLLQSLCELKLIKATHGVLTNARPDHLDVMGPTERDVAKALAAT
VPVGAKYFTAEDIHLDFFEYACKDRGSELIAATAQDAEKISDEEINKFVYSEFKINVALALKVTDDLGIPREIAIKGMWE
ATPDPGAMTEYNFNIKNAEINFANAFAANDPVSTKMLWDKLCAKYSGCDKKVLVVNCRDDREDRSKQMAEAALGWQKQDL
IVLIGTGTEVFTSFYKKYAKSLNKPMTKVIVCEEMTPIQILEKTVDSNPANSYILVGVGNIKDIGMELVDYCDTSHKKKH
NL

Sequences:

>Translated_402_residues
MDFWLIVVVFVILCVYLIIENIVHNNSIKSIPIRIHVNGTRGKSSVARLIAAGVRAGGYRTVAKTTGTLARYIDVDGSET
PVFRIGFSNIAEQVKIMFKARRAKADAIVIECMALQPLLQSLCELKLIKATHGVLTNARPDHLDVMGPTERDVAKALAAT
VPVGAKYFTAEDIHLDFFEYACKDRGSELIAATAQDAEKISDEEINKFVYSEFKINVALALKVTDDLGIPREIAIKGMWE
ATPDPGAMTEYNFNIKNAEINFANAFAANDPVSTKMLWDKLCAKYSGCDKKVLVVNCRDDREDRSKQMAEAALGWQKQDL
IVLIGTGTEVFTSFYKKYAKSLNKPMTKVIVCEEMTPIQILEKTVDSNPANSYILVGVGNIKDIGMELVDYCDTSHKKKH
NL
>Mature_402_residues
MDFWLIVVVFVILCVYLIIENIVHNNSIKSIPIRIHVNGTRGKSSVARLIAAGVRAGGYRTVAKTTGTLARYIDVDGSET
PVFRIGFSNIAEQVKIMFKARRAKADAIVIECMALQPLLQSLCELKLIKATHGVLTNARPDHLDVMGPTERDVAKALAAT
VPVGAKYFTAEDIHLDFFEYACKDRGSELIAATAQDAEKISDEEINKFVYSEFKINVALALKVTDDLGIPREIAIKGMWE
ATPDPGAMTEYNFNIKNAEINFANAFAANDPVSTKMLWDKLCAKYSGCDKKVLVVNCRDDREDRSKQMAEAALGWQKQDL
IVLIGTGTEVFTSFYKKYAKSLNKPMTKVIVCEEMTPIQILEKTVDSNPANSYILVGVGNIKDIGMELVDYCDTSHKKKH
NL

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapA and CapC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008337
- InterPro:   IPR013221 [H]

Pfam domain/function: PF08245 Mur_ligase_M [H]

EC number: NA

Molecular weight: Translated: 44566; Mature: 44566

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFWLIVVVFVILCVYLIIENIVHNNSIKSIPIRIHVNGTRGKSSVARLIAAGVRAGGYR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCE
TVAKTTGTLARYIDVDGSETPVFRIGFSNIAEQVKIMFKARRAKADAIVIECMALQPLLQ
EEHHHHCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SLCELKLIKATHGVLTNARPDHLDVMGPTERDVAKALAATVPVGAKYFTAEDIHLDFFEY
HHHHHHHHHHHHCHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
ACKDRGSELIAATAQDAEKISDEEINKFVYSEFKINVALALKVTDDLGIPREIAIKGMWE
HHHCCCCEEEEECHHHHHHCCHHHHHHHHHHHEEEEEEEEEEEECCCCCCHHHEEEECCC
ATPDPGAMTEYNFNIKNAEINFANAFAANDPVSTKMLWDKLCAKYSGCDKKVLVVNCRDD
CCCCCCCCEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
REDRSKQMAEAALGWQKQDLIVLIGTGTEVFTSFYKKYAKSLNKPMTKVIVCEEMTPIQI
HHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
LEKTVDSNPANSYILVGVGNIKDIGMELVDYCDTSHKKKHNL
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDFWLIVVVFVILCVYLIIENIVHNNSIKSIPIRIHVNGTRGKSSVARLIAAGVRAGGYR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCE
TVAKTTGTLARYIDVDGSETPVFRIGFSNIAEQVKIMFKARRAKADAIVIECMALQPLLQ
EEHHHHCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SLCELKLIKATHGVLTNARPDHLDVMGPTERDVAKALAATVPVGAKYFTAEDIHLDFFEY
HHHHHHHHHHHHCHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
ACKDRGSELIAATAQDAEKISDEEINKFVYSEFKINVALALKVTDDLGIPREIAIKGMWE
HHHCCCCEEEEECHHHHHHCCHHHHHHHHHHHEEEEEEEEEEEECCCCCCHHHEEEECCC
ATPDPGAMTEYNFNIKNAEINFANAFAANDPVSTKMLWDKLCAKYSGCDKKVLVVNCRDD
CCCCCCCCEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
REDRSKQMAEAALGWQKQDLIVLIGTGTEVFTSFYKKYAKSLNKPMTKVIVCEEMTPIQI
HHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
LEKTVDSNPANSYILVGVGNIKDIGMELVDYCDTSHKKKHNL
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10475962; 12004073; 2536679 [H]