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The map label for this gene is radC [C]

Identifier: 134300388

GI number: 134300388

Start: 2772747

End: 2773430

Strand: Reverse

Name: radC [C]

Synonym: Dred_2549

Alternate gene names: 134300388

Gene position: 2773430-2772747 (Counterclockwise)

Preceding gene: 134300389

Following gene: 134300387

Centisome position: 76.87

GC content: 44.15

Gene sequence:

>684_bases
ATGACTTATCCCGTAATACGTGAATTGCCCCCGGAAATGCGCCCCAGAGAACGTATGTTAAAAGAGGGCGCAGGGAGTCT
CACCGAAATTGATTTATTAGCTATTATGCTGCGCACAGGTACATCTAAAGTTTCTGTTTTGGAGTTAGCAGCAGAATTAT
TTAGTCACTTTAAGGACTTAAGAGCACTTTCTCAAGCAACAATTGAAGAACTAAGTCAGATTAAGGGAGTGGGACCTGTT
AAGGCTGTTCAGGTAAAGGCAGCCTTAGAACTGGGCCGTAGGTTGGCAGCGATGCCTGCTGAAACTAGGGTCATTATACG
GTGTCCGGAAGATGTTTGTGGCTTGGTTATGGAGGATCTAAGGGACTTGGATCGGGAGCACTTTTTAGCTCTCTTGCTTA
ATACCAAAAATCAGGTATTAGCCAGGGAAACCATCTCAATCGGCACACTAAATTCATCGGTTGTGCATCCCCGGGAACTG
TTTAAAGTTGCTATACGACGCAGTGCTGCCTCAATGATCTTAGTACACAACCATCCCAGTGGTGACCCGACACCCAGCCG
AGAAGACATTGTTTTAACCAAAAGATTGATCGAGGCAGGAGAAATTATTGGGATAGATGTCCTAGACCACATTATTATTG
GAGATAATAAGTTTACCAGTCTAAAGTCCAAAGGACTTATCTGA

Upstream 100 bases:

>100_bases
CCATTTTTATTGACAGCATTCGTGGTTGCTATTTTAGTGTTGTTGGTTTGCCTATATCGAAGCTGGCAGACGCATTACGA
ATGTTTGGAGTAGAAATTGT

Downstream 100 bases:

>100_bases
AACCCTAAGGAGGACAAAATATGAAACTTGGTATGTTTTCCAAGGATATGGGAATAGATTTGGGTACCGCAAACTCTTTG
GTTTATTTGAAAGGCAAAGG

Product: DNA repair protein RadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTYPVIRELPPEMRPRERMLKEGAGSLTEIDLLAIMLRTGTSKVSVLELAAELFSHFKDLRALSQATIEELSQIKGVGPV
KAVQVKAALELGRRLAAMPAETRVIIRCPEDVCGLVMEDLRDLDREHFLALLLNTKNQVLARETISIGTLNSSVVHPREL
FKVAIRRSAASMILVHNHPSGDPTPSREDIVLTKRLIEAGEIIGIDVLDHIIIGDNKFTSLKSKGLI

Sequences:

>Translated_227_residues
MTYPVIRELPPEMRPRERMLKEGAGSLTEIDLLAIMLRTGTSKVSVLELAAELFSHFKDLRALSQATIEELSQIKGVGPV
KAVQVKAALELGRRLAAMPAETRVIIRCPEDVCGLVMEDLRDLDREHFLALLLNTKNQVLARETISIGTLNSSVVHPREL
FKVAIRRSAASMILVHNHPSGDPTPSREDIVLTKRLIEAGEIIGIDVLDHIIIGDNKFTSLKSKGLI
>Mature_226_residues
TYPVIRELPPEMRPRERMLKEGAGSLTEIDLLAIMLRTGTSKVSVLELAAELFSHFKDLRALSQATIEELSQIKGVGPVK
AVQVKAALELGRRLAAMPAETRVIIRCPEDVCGLVMEDLRDLDREHFLALLLNTKNQVLARETISIGTLNSSVVHPRELF
KVAIRRSAASMILVHNHPSGDPTPSREDIVLTKRLIEAGEIIGIDVLDHIIIGDNKFTSLKSKGLI

Specific function: Involved In DNA Repair. [C]

COG id: COG2003

COG function: function code L; DNA repair proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0758 family

Homologues:

Organism=Escherichia coli, GI87082300, Length=213, Percent_Identity=37.5586854460094, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1788997, Length=105, Percent_Identity=46.6666666666667, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788312, Length=109, Percent_Identity=44.954128440367, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI2367100, Length=105, Percent_Identity=45.7142857142857, Blast_Score=104, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2549_DESRM (A4J7K6)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113884.1
- ProteinModelPortal:   A4J7K6
- SMR:   A4J7K6
- STRING:   A4J7K6
- GeneID:   4955624
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_2549
- eggNOG:   COG2003
- HOGENOM:   HBG751042
- OMA:   DKPREKL
- PhylomeDB:   A4J7K6
- ProtClustDB:   CLSK2537118
- BioCyc:   DRED349161:DRED_2549-MONOMER
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001405
- InterPro:   IPR020891
- SMART:   SM00278
- TIGRFAMs:   TIGR00608

Pfam domain/function: PF04002 DUF2466; SSF47781 RuvA_2_like

EC number: NA

Molecular weight: Translated: 25082; Mature: 24951

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS01302 UPF0758

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPVIRELPPEMRPRERMLKEGAGSLTEIDLLAIMLRTGTSKVSVLELAAELFSHFKDL
CCCCCHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RALSQATIEELSQIKGVGPVKAVQVKAALELGRRLAAMPAETRVIIRCPEDVCGLVMEDL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
RDLDREHFLALLLNTKNQVLARETISIGTLNSSVVHPRELFKVAIRRSAASMILVHNHPS
HHHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEECCC
GDPTPSREDIVLTKRLIEAGEIIGIDVLDHIIIGDNKFTSLKSKGLI
CCCCCCCCHHHHHHHHHHCCCEEEHHHHHHEEECCCCHHHHHHCCCC
>Mature Secondary Structure 
TYPVIRELPPEMRPRERMLKEGAGSLTEIDLLAIMLRTGTSKVSVLELAAELFSHFKDL
CCCCHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RALSQATIEELSQIKGVGPVKAVQVKAALELGRRLAAMPAETRVIIRCPEDVCGLVMEDL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
RDLDREHFLALLLNTKNQVLARETISIGTLNSSVVHPRELFKVAIRRSAASMILVHNHPS
HHHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEECCC
GDPTPSREDIVLTKRLIEAGEIIGIDVLDHIIIGDNKFTSLKSKGLI
CCCCCCCCHHHHHHHHHHCCCEEEHHHHHHEEECCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA