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The map label for this gene is mreB [H]

Identifier: 134300387

GI number: 134300387

Start: 2771695

End: 2772726

Strand: Reverse

Name: mreB [H]

Synonym: Dred_2548

Alternate gene names: 134300387

Gene position: 2772726-2771695 (Counterclockwise)

Preceding gene: 134300388

Following gene: 134300386

Centisome position: 76.85

GC content: 45.16

Gene sequence:

>1032_bases
ATGAAACTTGGTATGTTTTCCAAGGATATGGGAATAGATTTGGGTACCGCAAACTCTTTGGTTTATTTGAAAGGCAAAGG
AATAGTCTTGCGGGAGCCATCGGTTGTTGCAATTCAAAGAGAAACAGGACAAGTACTGGCAGTGGGGGAAGAGGCTAAAC
AAATGATTGGTCGTACCCCTGGAAATATTGTGGCCATACGTCCCATGAAAGATGGTGTTATTGCGGATTTTGACGTTACC
CAGAGTATGATTAAATATTTTATTAACAAAGCCCTGCGGAACCGTTCCTTCATTGTTAAGCCTAGGGTGGTTGTAAGTGT
ACCCTCTGGTGTAACCGCCGTTGAGGAAAGGGCAGTTCGTGAGGCTGCGTTACAGGCTGGTGCTAGGGAAGCCTACCTGA
TAGAAGAACCAATGGCAGCTGCCATTGGTGCAGGTTTACCAGTTCATGAACCCACAGGAAATATGATTGTGGACATTGGT
GGGGGTACCACTGAAGTTGCAGTTATATCGTTGGGTGGTATTGTAACCAGCCGCTCTATTCGGGTGGCCGGTGATGAAAT
GGATGATGCCATTATTCAACATGTCAAACGCACCTATAATTTAATGATCGGTGAGCGTACTGCTGAACAGATTAAACTGA
ATATCGGTACTGCCTATCCATTGGAGCAGGAAGAAACTGAAGAAATCAGGGGACGTGACCTAGTAACAGGATTACCAAAA
ACTCTGCAGATCACTTCCGCAGAAATCTATAAAGCTTTGTCGGAGCCCGTGGCTTCTATTTTGGAGGCTGTGAAGGTAAC
CCTTGAAAAAACGCCTCCGGAATTGGCTGCAGATATTATGGACCGTGGTATTGTTATGGCTGGTGGGGGTTCATTACTTC
GGGGACTAGATCGTCTGGTCAGTGATCAGACAGGAATGCCGGTTCATATGGCAGAGGAGCCACTTTTAGCAGTGGCCTAT
GGTTCCGGTAGAGTTCTTGAGAATATTGATATTTTAAAACGTGTATTAATTCAACCTAAGAAGTTGGCTTAA

Upstream 100 bases:

>100_bases
TTATTGGGATAGATGTCCTAGACCACATTATTATTGGAGATAATAAGTTTACCAGTCTAAAGTCCAAAGGACTTATCTGA
AACCCTAAGGAGGACAAAAT

Downstream 100 bases:

>100_bases
AGGTTGTGAGAAATTTTGCCCCGTAATGTATCCTACAAAAATTTAATTTTACTCGTTATTTTGGTGGGTATAACCCTTCT
GGTTATGCGTTTTACTAATC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKLGMFSKDMGIDLGTANSLVYLKGKGIVLREPSVVAIQRETGQVLAVGEEAKQMIGRTPGNIVAIRPMKDGVIADFDVT
QSMIKYFINKALRNRSFIVKPRVVVSVPSGVTAVEERAVREAALQAGAREAYLIEEPMAAAIGAGLPVHEPTGNMIVDIG
GGTTEVAVISLGGIVTSRSIRVAGDEMDDAIIQHVKRTYNLMIGERTAEQIKLNIGTAYPLEQEETEEIRGRDLVTGLPK
TLQITSAEIYKALSEPVASILEAVKVTLEKTPPELAADIMDRGIVMAGGGSLLRGLDRLVSDQTGMPVHMAEEPLLAVAY
GSGRVLENIDILKRVLIQPKKLA

Sequences:

>Translated_343_residues
MKLGMFSKDMGIDLGTANSLVYLKGKGIVLREPSVVAIQRETGQVLAVGEEAKQMIGRTPGNIVAIRPMKDGVIADFDVT
QSMIKYFINKALRNRSFIVKPRVVVSVPSGVTAVEERAVREAALQAGAREAYLIEEPMAAAIGAGLPVHEPTGNMIVDIG
GGTTEVAVISLGGIVTSRSIRVAGDEMDDAIIQHVKRTYNLMIGERTAEQIKLNIGTAYPLEQEETEEIRGRDLVTGLPK
TLQITSAEIYKALSEPVASILEAVKVTLEKTPPELAADIMDRGIVMAGGGSLLRGLDRLVSDQTGMPVHMAEEPLLAVAY
GSGRVLENIDILKRVLIQPKKLA
>Mature_343_residues
MKLGMFSKDMGIDLGTANSLVYLKGKGIVLREPSVVAIQRETGQVLAVGEEAKQMIGRTPGNIVAIRPMKDGVIADFDVT
QSMIKYFINKALRNRSFIVKPRVVVSVPSGVTAVEERAVREAALQAGAREAYLIEEPMAAAIGAGLPVHEPTGNMIVDIG
GGTTEVAVISLGGIVTSRSIRVAGDEMDDAIIQHVKRTYNLMIGERTAEQIKLNIGTAYPLEQEETEEIRGRDLVTGLPK
TLQITSAEIYKALSEPVASILEAVKVTLEKTPPELAADIMDRGIVMAGGGSLLRGLDRLVSDQTGMPVHMAEEPLLAVAY
GSGRVLENIDILKRVLIQPKKLA

Specific function: Involved in formation of the rod shape of the cell [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=332, Percent_Identity=59.9397590361446, Blast_Score=395, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17534015, Length=384, Percent_Identity=24.21875, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534013, Length=384, Percent_Identity=24.21875, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324120, Length=390, Percent_Identity=23.3333333333333, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319972, Length=390, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319396, Length=241, Percent_Identity=26.5560165975104, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36803; Mature: 36803

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGMFSKDMGIDLGTANSLVYLKGKGIVLREPSVVAIQRETGQVLAVGEEAKQMIGRTP
CCCCCCCCCCCCEECCCCCEEEEECCEEEEECCCEEEEEECCCCEEEECHHHHHHHCCCC
GNIVAIRPMKDGVIADFDVTQSMIKYFINKALRNRSFIVKPRVVVSVPSGVTAVEERAVR
CCEEEEEECCCCCEECHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCHHHHHHHHH
EAALQAGAREAYLIEEPMAAAIGAGLPVHEPTGNMIVDIGGGTTEVAVISLGGIVTSRSI
HHHHHCCCCCEEEECCCHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEECCEEECCEE
RVAGDEMDDAIIQHVKRTYNLMIGERTAEQIKLNIGTAYPLEQEETEEIRGRDLVTGLPK
EECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHCCCHHHHCCCC
TLQITSAEIYKALSEPVASILEAVKVTLEKTPPELAADIMDRGIVMAGGGSLLRGLDRLV
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHHHHHHHH
SDQTGMPVHMAEEPLLAVAYGSGRVLENIDILKRVLIQPKKLA
CCCCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLGMFSKDMGIDLGTANSLVYLKGKGIVLREPSVVAIQRETGQVLAVGEEAKQMIGRTP
CCCCCCCCCCCCEECCCCCEEEEECCEEEEECCCEEEEEECCCCEEEECHHHHHHHCCCC
GNIVAIRPMKDGVIADFDVTQSMIKYFINKALRNRSFIVKPRVVVSVPSGVTAVEERAVR
CCEEEEEECCCCCEECHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCHHHHHHHHH
EAALQAGAREAYLIEEPMAAAIGAGLPVHEPTGNMIVDIGGGTTEVAVISLGGIVTSRSI
HHHHHCCCCCEEEECCCHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEECCEEECCEE
RVAGDEMDDAIIQHVKRTYNLMIGERTAEQIKLNIGTAYPLEQEETEEIRGRDLVTGLPK
EECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHCCCHHHHCCCC
TLQITSAEIYKALSEPVASILEAVKVTLEKTPPELAADIMDRGIVMAGGGSLLRGLDRLV
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHHHHHHHH
SDQTGMPVHMAEEPLLAVAYGSGRVLENIDILKRVLIQPKKLA
CCCCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377; 8387996 [H]