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The map label for this gene is glyQ

Identifier: 134300312

GI number: 134300312

Start: 2695851

End: 2696738

Strand: Reverse

Name: glyQ

Synonym: Dred_2473

Alternate gene names: 134300312

Gene position: 2696738-2695851 (Counterclockwise)

Preceding gene: 134300313

Following gene: 134300311

Centisome position: 74.74

GC content: 48.31

Gene sequence:

>888_bases
GTGAACTTTCAGGAACTCATTCTGACCTTGAACAAATTCTGGGCCGAACAAAATTGTATTATTCAACAGCCCTACGACAT
CGAAAAGGGCGCCGGCACCATGAACCCGGCTACCTTTTTACGGGCCCTGGGACCAGAACCTTGGCGGGTGGCCTATGTGG
AACCATCTCGTCGTCCCACCGACGGTCGCTATGGAGAAAACCCCAACCGCCTGCAGCATTACTTCCAATACCAGGTCATT
TTAAAACCTTCCCCCGACGATGTTATTCCCGTTTATTTAGACTCCCTACGGGCTATCGGCATTGATCCGGATAAGCATGA
TATTCGCTTTGTGGAAGACAACTGGGAATCCCCCACCCTGGGTGCCTGGGGATTGGGTTGGGAAGTGTGGCTGGATGGTA
TGGAGGTAACCCAGTTTACCTACTTCCAGCAGTGTGGCGGTATCGACTGTCACCCGGTATCTGCAGAGATCACCTATGGT
CTAGAAAGATTAGCCATGTTCATTCAACAAAAGGATAGTGTTTACGATATTACCTGGGTAGGAGATATCACCTATGGAGA
TGTTTACCACCAGAATGAAGTAGAACAATCGGGCTATAACTTTGAAGTGGCCAATACTGAGATGCTCTTTGACCTCTTTG
ATATGTATGAGGCAGAAGCCAACCATATACTGGAAAAAGGTTTAGTTCTCCCAGCCTATGACTATGTTTTAAAATGCTCC
CATACCTTTAACTTATTGGATGCCAGAGGGGCCATCAGTGTCTCTGAACGGCAGGGCTTTATTGCCCGGGTAAGGCAGAT
GGCCAGGGCCTGCGCCCATGCCTATGTGGAGCAGCGTGAAAAATTAGGATTTCCTCTGTTAAAGAAAGGGGGCAATATCA
ATGGCTAA

Upstream 100 bases:

>100_bases
TTAATTTAACCCCCAAAATTGGAGAATAGATAATCCCAAGCCAAACAGAAGTGGGAAATCCACCAGGTGTTTAGTTTTAT
TAAATAAGGAGGCAAAAACA

Downstream 100 bases:

>100_bases
GGATTTTTTATTGGAAGTTGGTATCGAAGAAATGCCTGCCCGTTTTTTGGGTCCGGCTTTAACACAATTAAAGGAACAAA
CGGTCAAAACCCTGCAGGAA

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNFQELILTLNKFWAEQNCIIQQPYDIEKGAGTMNPATFLRALGPEPWRVAYVEPSRRPTDGRYGENPNRLQHYFQYQVI
LKPSPDDVIPVYLDSLRAIGIDPDKHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQCGGIDCHPVSAEITYG
LERLAMFIQQKDSVYDITWVGDITYGDVYHQNEVEQSGYNFEVANTEMLFDLFDMYEAEANHILEKGLVLPAYDYVLKCS
HTFNLLDARGAISVSERQGFIARVRQMARACAHAYVEQREKLGFPLLKKGGNING

Sequences:

>Translated_295_residues
MNFQELILTLNKFWAEQNCIIQQPYDIEKGAGTMNPATFLRALGPEPWRVAYVEPSRRPTDGRYGENPNRLQHYFQYQVI
LKPSPDDVIPVYLDSLRAIGIDPDKHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQCGGIDCHPVSAEITYG
LERLAMFIQQKDSVYDITWVGDITYGDVYHQNEVEQSGYNFEVANTEMLFDLFDMYEAEANHILEKGLVLPAYDYVLKCS
HTFNLLDARGAISVSERQGFIARVRQMARACAHAYVEQREKLGFPLLKKGGNING
>Mature_295_residues
MNFQELILTLNKFWAEQNCIIQQPYDIEKGAGTMNPATFLRALGPEPWRVAYVEPSRRPTDGRYGENPNRLQHYFQYQVI
LKPSPDDVIPVYLDSLRAIGIDPDKHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQCGGIDCHPVSAEITYG
LERLAMFIQQKDSVYDITWVGDITYGDVYHQNEVEQSGYNFEVANTEMLFDLFDMYEAEANHILEKGLVLPAYDYVLKCS
HTFNLLDARGAISVSERQGFIARVRQMARACAHAYVEQREKLGFPLLKKGGNING

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=294, Percent_Identity=65.3061224489796, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_DESRM (A4J7D0)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113808.1
- ProteinModelPortal:   A4J7D0
- SMR:   A4J7D0
- STRING:   A4J7D0
- GeneID:   4957152
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_2473
- eggNOG:   COG0752
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- PhylomeDB:   A4J7D0
- ProtClustDB:   PRK09348
- BioCyc:   DRED349161:DRED_2473-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 33839; Mature: 33839

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQELILTLNKFWAEQNCIIQQPYDIEKGAGTMNPATFLRALGPEPWRVAYVEPSRRPT
CCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCC
DGRYGENPNRLQHYFQYQVILKPSPDDVIPVYLDSLRAIGIDPDKHDIRFVEDNWESPTL
CCCCCCCHHHHHHEEEEEEEECCCCCCEEHHHHHCHHEECCCCCCCCEEEEECCCCCCCC
GAWGLGWEVWLDGMEVTQFTYFQQCGGIDCHPVSAEITYGLERLAMFIQQKDSVYDITWV
CCCCCCHHHEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
GDITYGDVYHQNEVEQSGYNFEVANTEMLFDLFDMYEAEANHILEKGLVLPAYDYVLKCS
ECCCCCCCCCCCCHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECC
HTFNLLDARGAISVSERQGFIARVRQMARACAHAYVEQREKLGFPLLKKGGNING
CHHEEEECCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MNFQELILTLNKFWAEQNCIIQQPYDIEKGAGTMNPATFLRALGPEPWRVAYVEPSRRPT
CCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCC
DGRYGENPNRLQHYFQYQVILKPSPDDVIPVYLDSLRAIGIDPDKHDIRFVEDNWESPTL
CCCCCCCHHHHHHEEEEEEEECCCCCCEEHHHHHCHHEECCCCCCCCEEEEECCCCCCCC
GAWGLGWEVWLDGMEVTQFTYFQQCGGIDCHPVSAEITYGLERLAMFIQQKDSVYDITWV
CCCCCCHHHEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
GDITYGDVYHQNEVEQSGYNFEVANTEMLFDLFDMYEAEANHILEKGLVLPAYDYVLKCS
ECCCCCCCCCCCCHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECC
HTFNLLDARGAISVSERQGFIARVRQMARACAHAYVEQREKLGFPLLKKGGNING
CHHEEEECCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA