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The map label for this gene is mcpA [H]

Identifier: 134300300

GI number: 134300300

Start: 2677420

End: 2679300

Strand: Reverse

Name: mcpA [H]

Synonym: Dred_2461

Alternate gene names: 134300300

Gene position: 2679300-2677420 (Counterclockwise)

Preceding gene: 134300301

Following gene: 134300299

Centisome position: 74.26

GC content: 44.28

Gene sequence:

>1881_bases
TTGCAGCAGAGTGTGAAGGCAAAATTATTGATACCGCTGATTATGATTTTTGGAGTTTCATTAATCACCCTTGTTTCCTT
AAATCATTATCAAATGAGAAGTGCTATCCTAAGCCAGGAGCAGGTAAGTTTCCGGAATATTGAAAGTATTGTTCGCAACG
ACTTGGAGGCAACTTTTACTTCCACTCGCATGGGGCTGACCAGTGTTATTAATATGCCGGAAGTGCAGCAGGCCTTTGCA
CGAAGGGACCGGGAAGAACTGCAACGACTTACCGCACCCATTTTTGAGCAAGCTAAAAAGGATGGTATTGAACAGTTTCA
GTTTCACTTGCCCCCAGCTACCTCTTTCCTGCGTCTGCATCAACCACAAAAGTATGGGGACGACCTGTCATCTTTCCGAG
CCACCGTGGTTCAAAGTAATCAAGAAAAGAAACTGGTGGCTGGGTTAGAAGAGGGACGAGGTGGTTATGGTTTCCGGGTG
GTGGCCCCTGTTTTTTTTCAGGGACAACATGTAGGAAGTGCCGAATATGGCATGGGCTTTAGCCCTACAATCTTAGAACG
TTGGAAGGAACAGTGCGGTGGAGATTTCTATATGTATCCCTTTGCCAGTTCCGAAGTTGCTTGGCAAAGGGTTGACAAAA
GCAAACCATTGGTGGGTACAGCAAAGGAAGATCCTCTTAAAATAGATGAAAATGAGATAAAGAAAGCCATGTCCAGCAAA
GGTGTCTACGCCAGCTATGTAAACGGTGATAACCATGCGATTCTGATTATTCCGGTTTATGACTACAGTGGGAAACCCAT
CAGCTATGTGAAGGCGAACCTGGACCGTACCGAAGTCTTAAATAAATTGGATACCGTGTTGCGGGACAGCATAGTCCACC
TACTTTTATCACTCTTGATAATTTCCCTAATTATGTATTGGTTAATTACGATCACATTAAAGCCACTGCAAAGAATCAGT
GATAATATGACTACCGTAGCCAGTGGAGACTTAACCAAGAAATTGCAGTTGCAAGGTAATGATGAGATCTCTAAACTGGG
ACAAAGTTTTAATACCATGCTGAAGGATTTTCGGCGTTTAATTGGAGAAACACGTTATATAACCGGGGAACTCACTAAGT
CCAGCAAGGCCCTCAGTATGGTAACGGAAGAAACCAGTGTTTCAGTGGAGGAAGCAACTGAACAGGTAGAAAAATTAGCC
TATTCTTTGCAGGAATTGGATACGATGGCCAAGCATGCAGCGGATTATTCCCAACAAGCAGCCGGAGCTGCAGAGGAAGG
CCAGCAAGTAGTCCAACAAGCAGTTAAACAGATACAAATTTTGGATAGCATGGTGGAAGGCTTGTCTCAGGAAACTGGTG
GACTTGGACAAAAGATCGAAGATGTTAACAAGTTTGTACAGCTCATTAGCGAAATCGCAGAGCAAACAAACCTGCTGGCA
TTGAATGCCGCCATTGAGTCTGCCAGGGCAGGGGAGCATGGACGAGGTTTTTCTGTGGTAGCCCAGGAGGTTCGTAAGTT
AGCCGACCGCTCCAATCAGGCAGCCAAAGATGTAAAGAATATTATTATAGAAATAACAGAGCAATCCGAAAATGTCATGT
TTAACATGAATGAAGGGTTAAAGGAAGTCCATGCAAGCCACCAATTGATTAACGAATCGGGAGTAAAATTTAAACGGATT
AAAGAGCTTGTAGAATTAATGGCGCAACAATCCCAAGCCGTGGCTGTTTCTGGTAGCCAGGCTACGGCCAGTAGTTCTGA
AATATCAGCAGCCATTCAAGAACAAGCTGCTTCCATTCAACAAGTAGCAACCTCTGCAGGTGTCTTAGACCAAATGGCAG
AGGACCTAAAGCAACAACTGAGCCGGTTTAAAAGTAGCTAG

Upstream 100 bases:

>100_bases
TAAAAAAGAGATATCCACAGGACATCATGTGAAAGAAATATCATGTATTTTATAATCATCGTTCTATGAAAAATTTCCCA
ATATAAGGGGGTTAAGAAGT

Downstream 100 bases:

>100_bases
GATGACAAAGGGTTCTGGGAAATCATTCCCGAGCCCTTTTTTGTACCTGGCCACTAGGCAGAAGCCAGTTTTTCTGTGGA
ACTGGCAATACTACAGGAAG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H1 [H]

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MQQSVKAKLLIPLIMIFGVSLITLVSLNHYQMRSAILSQEQVSFRNIESIVRNDLEATFTSTRMGLTSVINMPEVQQAFA
RRDREELQRLTAPIFEQAKKDGIEQFQFHLPPATSFLRLHQPQKYGDDLSSFRATVVQSNQEKKLVAGLEEGRGGYGFRV
VAPVFFQGQHVGSAEYGMGFSPTILERWKEQCGGDFYMYPFASSEVAWQRVDKSKPLVGTAKEDPLKIDENEIKKAMSSK
GVYASYVNGDNHAILIIPVYDYSGKPISYVKANLDRTEVLNKLDTVLRDSIVHLLLSLLIISLIMYWLITITLKPLQRIS
DNMTTVASGDLTKKLQLQGNDEISKLGQSFNTMLKDFRRLIGETRYITGELTKSSKALSMVTEETSVSVEEATEQVEKLA
YSLQELDTMAKHAADYSQQAAGAAEEGQQVVQQAVKQIQILDSMVEGLSQETGGLGQKIEDVNKFVQLISEIAEQTNLLA
LNAAIESARAGEHGRGFSVVAQEVRKLADRSNQAAKDVKNIIIEITEQSENVMFNMNEGLKEVHASHQLINESGVKFKRI
KELVELMAQQSQAVAVSGSQATASSSEISAAIQEQAASIQQVATSAGVLDQMAEDLKQQLSRFKSS

Sequences:

>Translated_626_residues
MQQSVKAKLLIPLIMIFGVSLITLVSLNHYQMRSAILSQEQVSFRNIESIVRNDLEATFTSTRMGLTSVINMPEVQQAFA
RRDREELQRLTAPIFEQAKKDGIEQFQFHLPPATSFLRLHQPQKYGDDLSSFRATVVQSNQEKKLVAGLEEGRGGYGFRV
VAPVFFQGQHVGSAEYGMGFSPTILERWKEQCGGDFYMYPFASSEVAWQRVDKSKPLVGTAKEDPLKIDENEIKKAMSSK
GVYASYVNGDNHAILIIPVYDYSGKPISYVKANLDRTEVLNKLDTVLRDSIVHLLLSLLIISLIMYWLITITLKPLQRIS
DNMTTVASGDLTKKLQLQGNDEISKLGQSFNTMLKDFRRLIGETRYITGELTKSSKALSMVTEETSVSVEEATEQVEKLA
YSLQELDTMAKHAADYSQQAAGAAEEGQQVVQQAVKQIQILDSMVEGLSQETGGLGQKIEDVNKFVQLISEIAEQTNLLA
LNAAIESARAGEHGRGFSVVAQEVRKLADRSNQAAKDVKNIIIEITEQSENVMFNMNEGLKEVHASHQLINESGVKFKRI
KELVELMAQQSQAVAVSGSQATASSSEISAAIQEQAASIQQVATSAGVLDQMAEDLKQQLSRFKSS
>Mature_626_residues
MQQSVKAKLLIPLIMIFGVSLITLVSLNHYQMRSAILSQEQVSFRNIESIVRNDLEATFTSTRMGLTSVINMPEVQQAFA
RRDREELQRLTAPIFEQAKKDGIEQFQFHLPPATSFLRLHQPQKYGDDLSSFRATVVQSNQEKKLVAGLEEGRGGYGFRV
VAPVFFQGQHVGSAEYGMGFSPTILERWKEQCGGDFYMYPFASSEVAWQRVDKSKPLVGTAKEDPLKIDENEIKKAMSSK
GVYASYVNGDNHAILIIPVYDYSGKPISYVKANLDRTEVLNKLDTVLRDSIVHLLLSLLIISLIMYWLITITLKPLQRIS
DNMTTVASGDLTKKLQLQGNDEISKLGQSFNTMLKDFRRLIGETRYITGELTKSSKALSMVTEETSVSVEEATEQVEKLA
YSLQELDTMAKHAADYSQQAAGAAEEGQQVVQQAVKQIQILDSMVEGLSQETGGLGQKIEDVNKFVQLISEIAEQTNLLA
LNAAIESARAGEHGRGFSVVAQEVRKLADRSNQAAKDVKNIIIEITEQSENVMFNMNEGLKEVHASHQLINESGVKFKRI
KELVELMAQQSQAVAVSGSQATASSSEISAAIQEQAASIQQVATSAGVLDQMAEDLKQQLSRFKSS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=334, Percent_Identity=29.0419161676647, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=28.8343558282209, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788194, Length=331, Percent_Identity=28.7009063444109, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788195, Length=317, Percent_Identity=30.2839116719243, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789453, Length=341, Percent_Identity=25.2199413489736, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 69374; Mature: 69374

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSVKAKLLIPLIMIFGVSLITLVSLNHYQMRSAILSQEQVSFRNIESIVRNDLEATFT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STRMGLTSVINMPEVQQAFARRDREELQRLTAPIFEQAKKDGIEQFQFHLPPATSFLRLH
HHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHEECCCHHHHHHHC
QPQKYGDDLSSFRATVVQSNQEKKLVAGLEEGRGGYGFRVVAPVFFQGQHVGSAEYGMGF
CCHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCCCCCCCCCC
SPTILERWKEQCGGDFYMYPFASSEVAWQRVDKSKPLVGTAKEDPLKIDENEIKKAMSSK
CHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
GVYASYVNGDNHAILIIPVYDYSGKPISYVKANLDRTEVLNKLDTVLRDSIVHLLLSLLI
CCEEEEECCCCCEEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISLIMYWLITITLKPLQRISDNMTTVASGDLTKKLQLQGNDEISKLGQSFNTMLKDFRRL
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
IGETRYITGELTKSSKALSMVTEETSVSVEEATEQVEKLAYSLQELDTMAKHAADYSQQA
HCCCCEEEHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGAAEEGQQVVQQAVKQIQILDSMVEGLSQETGGLGQKIEDVNKFVQLISEIAEQTNLLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCEEH
LNAAIESARAGEHGRGFSVVAQEVRKLADRSNQAAKDVKNIIIEITEQSENVMFNMNEGL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECHHHH
KEVHASHQLINESGVKFKRIKELVELMAQQSQAVAVSGSQATASSSEISAAIQEQAASIQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH
QVATSAGVLDQMAEDLKQQLSRFKSS
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQSVKAKLLIPLIMIFGVSLITLVSLNHYQMRSAILSQEQVSFRNIESIVRNDLEATFT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STRMGLTSVINMPEVQQAFARRDREELQRLTAPIFEQAKKDGIEQFQFHLPPATSFLRLH
HHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHEECCCHHHHHHHC
QPQKYGDDLSSFRATVVQSNQEKKLVAGLEEGRGGYGFRVVAPVFFQGQHVGSAEYGMGF
CCHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCCCCCCCCCC
SPTILERWKEQCGGDFYMYPFASSEVAWQRVDKSKPLVGTAKEDPLKIDENEIKKAMSSK
CHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
GVYASYVNGDNHAILIIPVYDYSGKPISYVKANLDRTEVLNKLDTVLRDSIVHLLLSLLI
CCEEEEECCCCCEEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISLIMYWLITITLKPLQRISDNMTTVASGDLTKKLQLQGNDEISKLGQSFNTMLKDFRRL
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
IGETRYITGELTKSSKALSMVTEETSVSVEEATEQVEKLAYSLQELDTMAKHAADYSQQA
HCCCCEEEHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGAAEEGQQVVQQAVKQIQILDSMVEGLSQETGGLGQKIEDVNKFVQLISEIAEQTNLLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCEEH
LNAAIESARAGEHGRGFSVVAQEVRKLADRSNQAAKDVKNIIIEITEQSENVMFNMNEGL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECHHHH
KEVHASHQLINESGVKFKRIKELVELMAQQSQAVAVSGSQATASSSEISAAIQEQAASIQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH
QVATSAGVLDQMAEDLKQQLSRFKSS
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]