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The map label for this gene is 134300207

Identifier: 134300207

GI number: 134300207

Start: 2593243

End: 2593491

Strand: Reverse

Name: 134300207

Synonym: Dred_2368

Alternate gene names: NA

Gene position: 2593491-2593243 (Counterclockwise)

Preceding gene: 134300208

Following gene: 134300206

Centisome position: 71.88

GC content: 41.37

Gene sequence:

>249_bases
GTGTTTCAAGCAAAGATTTACGTTACCCTTAGGAAAAGTGTATTGGACCCCCAGGGAAATGTAGTGCGTAAATCCCTTTG
TGCCCTGGGCTATTCCAATGTTCCTGAAGTACGTATTGGACGTTATATGGTGGTTGATATAGAAATCACTGACAGGGCTG
AAGCAGAAAAACAGGTACGTGATATGTGTGATAAATTGCTGGTTAATCCGGTAATTGAAGACTATACATTTGAACTGGTG
GAGGTGTAA

Upstream 100 bases:

>100_bases
ACAAAATTCCCCTATAATATAATAAAGGTTTTTTAGTAAAAAGCAATAGTTTTTCTTAAAATTTAAATGGGCTGTGGCCT
GAAAATAAGGAGGGCTTAGC

Downstream 100 bases:

>100_bases
AGCGTGAAATTTGGAGTGGTGGTTTTTCCTGGCTCCAATTGTGACGCCGATTGCCTGCATGCCATTAAAACTGTTACCGG
GCAGCCGGTGGATTACATTT

Product: phosphoribosylformylglycinamidine synthase PurS

Products: ADP; phosphate; 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 82

Protein sequence:

>82_residues
MFQAKIYVTLRKSVLDPQGNVVRKSLCALGYSNVPEVRIGRYMVVDIEITDRAEAEKQVRDMCDKLLVNPVIEDYTFELV
EV

Sequences:

>Translated_82_residues
MFQAKIYVTLRKSVLDPQGNVVRKSLCALGYSNVPEVRIGRYMVVDIEITDRAEAEKQVRDMCDKLLVNPVIEDYTFELV
EV
>Mature_82_residues
MFQAKIYVTLRKSVLDPQGNVVRKSLCALGYSNVPEVRIGRYMVVDIEITDRAEAEKQVRDMCDKLLVNPVIEDYTFELV
EV

Specific function: Unknown

COG id: COG1828

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0062 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003850
- ProDom:   PD010362 [H]

Pfam domain/function: PF02700 PurS [H]

EC number: 6.3.5.3

Molecular weight: Translated: 9422; Mature: 9422

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQAKIYVTLRKSVLDPQGNVVRKSLCALGYSNVPEVRIGRYMVVDIEITDRAEAEKQVR
CCCEEEEEEEECHHCCCCCHHHHHHHHHCCCCCCCCEECCCEEEEEEEECCCHHHHHHHH
DMCDKLLVNPVIEDYTFELVEV
HHHHHHHHCHHHHCCEEEEECC
>Mature Secondary Structure
MFQAKIYVTLRKSVLDPQGNVVRKSLCALGYSNVPEVRIGRYMVVDIEITDRAEAEKQVR
CCCEEEEEEEECHHCCCCCHHHHHHHHHCCCCCCCCEECCCEEEEEEEECCCHHHHHHHH
DMCDKLLVNPVIEDYTFELVEV
HHHHHHHHCHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide; L-glutamine; H2O

Specific reaction: ATP + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]