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The map label for this gene is purQ [H]

Identifier: 134300206

GI number: 134300206

Start: 2592538

End: 2593239

Strand: Reverse

Name: purQ [H]

Synonym: Dred_2367

Alternate gene names: 134300206

Gene position: 2593239-2592538 (Counterclockwise)

Preceding gene: 134300207

Following gene: 134300205

Centisome position: 71.87

GC content: 47.01

Gene sequence:

>702_bases
GTGAAATTTGGAGTGGTGGTTTTTCCTGGCTCCAATTGTGACGCCGATTGCCTGCATGCCATTAAAACTGTTACCGGGCA
GCCGGTGGATTACATTTGGCACAAGTCTGGCAGCGTGGATGGTTATGACTGCATCGTGCTGCCTGGGGGATTCTCCTATG
GAGATTATTTGCGATGCGGCGCTGTGGCAAGGTTTTCCCCTGTGATGTCACCGGTTATTGAATTTGCCCGCAGGGGTGGA
CTGGTGCTGGGAATTTGCAATGGATTTCAGGTTTTGACCGAAGCAGGTCTTTTACCCGGAGCCCTACATCGAAATAAAAA
TTTATCTTTCCTTTGTCATGACACCTATTTAAGGGTGGAGAATGATATTTCTCCCTTTACTTCATTGGCCAGCCGGGGTA
GTGTTATTAAGGTTCCCATTGCCCATGGTGAGGGAAATTATTTTGCGGATTCAGACACGGTCCGTCGTTTAGAAGAAAAT
AATCAGGTTGTGTTCCGTTATTGTGATTACAATGGCGAAATTACACAGGGAGTCAATCCCAATGGTTCTGTAAACAACAT
TGCTGGTATTTGCAATGAGCAGGGCAATGTGCTGGGCATGATGCCCCACCCGGAACGCTGTGCCGAAGAAATACTGGGTA
ATATTGATGGACAACTGATTTTTAAATCCTTGCTGGAAACCTGGCAGAGGAGGTGTGGCTAA

Upstream 100 bases:

>100_bases
CAGGGCTGAAGCAGAAAAACAGGTACGTGATATGTGTGATAAATTGCTGGTTAATCCGGTAATTGAAGACTATACATTTG
AACTGGTGGAGGTGTAAAGC

Downstream 100 bases:

>100_bases
TGATAGTGGAGGAAAAGGTTTGGCGGGAGATGGGCCTGACTGACTCTGAGTATGAAAGGATCGTAGAGATTCTGGGTCGC
CACCCTAACTATGTAGAAGT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKFGVVVFPGSNCDADCLHAIKTVTGQPVDYIWHKSGSVDGYDCIVLPGGFSYGDYLRCGAVARFSPVMSPVIEFARRGG
LVLGICNGFQVLTEAGLLPGALHRNKNLSFLCHDTYLRVENDISPFTSLASRGSVIKVPIAHGEGNYFADSDTVRRLEEN
NQVVFRYCDYNGEITQGVNPNGSVNNIAGICNEQGNVLGMMPHPERCAEEILGNIDGQLIFKSLLETWQRRCG

Sequences:

>Translated_233_residues
MKFGVVVFPGSNCDADCLHAIKTVTGQPVDYIWHKSGSVDGYDCIVLPGGFSYGDYLRCGAVARFSPVMSPVIEFARRGG
LVLGICNGFQVLTEAGLLPGALHRNKNLSFLCHDTYLRVENDISPFTSLASRGSVIKVPIAHGEGNYFADSDTVRRLEEN
NQVVFRYCDYNGEITQGVNPNGSVNNIAGICNEQGNVLGMMPHPERCAEEILGNIDGQLIFKSLLETWQRRCG
>Mature_233_residues
MKFGVVVFPGSNCDADCLHAIKTVTGQPVDYIWHKSGSVDGYDCIVLPGGFSYGDYLRCGAVARFSPVMSPVIEFARRGG
LVLGICNGFQVLTEAGLLPGALHRNKNLSFLCHDTYLRVENDISPFTSLASRGSVIKVPIAHGEGNYFADSDTVRRLEEN
NQVVFRYCDYNGEITQGVNPNGSVNNIAGICNEQGNVLGMMPHPERCAEEILGNIDGQLIFKSLLETWQRRCG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=200, Percent_Identity=30.5, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI48994899, Length=207, Percent_Identity=32.3671497584541, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17553022, Length=232, Percent_Identity=26.2931034482759, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321498, Length=181, Percent_Identity=34.2541436464088, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24582111, Length=193, Percent_Identity=35.2331606217617, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24582109, Length=193, Percent_Identity=35.2331606217617, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17137292, Length=193, Percent_Identity=35.2331606217617, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25452; Mature: 25452

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGVVVFPGSNCDADCLHAIKTVTGQPVDYIWHKSGSVDGYDCIVLPGGFSYGDYLRCG
CCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHC
AVARFSPVMSPVIEFARRGGLVLGICNGFQVLTEAGLLPGALHRNKNLSFLCHDTYLRVE
CHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCHHHCCCCCEEEEECEEEEEC
NDISPFTSLASRGSVIKVPIAHGEGNYFADSDTVRRLEENNQVVFRYCDYNGEITQGVNP
CCCCHHHHHHCCCCEEEEEEEECCCCEECCHHHHHHHHCCCCEEEEEECCCCEECCCCCC
NGSVNNIAGICNEQGNVLGMMPHPERCAEEILGNIDGQLIFKSLLETWQRRCG
CCCCHHHHHEECCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFGVVVFPGSNCDADCLHAIKTVTGQPVDYIWHKSGSVDGYDCIVLPGGFSYGDYLRCG
CCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHC
AVARFSPVMSPVIEFARRGGLVLGICNGFQVLTEAGLLPGALHRNKNLSFLCHDTYLRVE
CHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCHHHCCCCCEEEEECEEEEEC
NDISPFTSLASRGSVIKVPIAHGEGNYFADSDTVRRLEENNQVVFRYCDYNGEITQGVNP
CCCCHHHHHHCCCCEEEEEEEECCCCEECCHHHHHHHHCCCCEEEEEECCCCEECCCCCC
NGSVNNIAGICNEQGNVLGMMPHPERCAEEILGNIDGQLIFKSLLETWQRRCG
CCCCHHHHHEECCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA