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The map label for this gene is moaC

Identifier: 134300106

GI number: 134300106

Start: 2479469

End: 2479963

Strand: Reverse

Name: moaC

Synonym: Dred_2267

Alternate gene names: 134300106

Gene position: 2479963-2479469 (Counterclockwise)

Preceding gene: 134300107

Following gene: 134300105

Centisome position: 68.73

GC content: 48.08

Gene sequence:

>495_bases
TTGTCCGAGTTAACACATTTCGATGCCAAGGGTAATGCCTGGATGGTGGATATAACAGAAAAAGAAGAAACCCATCGTGT
GGCCGAGGTCAGGGGAGAGGTTGTCATGGCACCGGCCACACTGGAATTAATTCAACAGGGCGGTATGGCCAAAGGGGATG
TACTGGGGGTTGCAAGGGTTGCCGGAATTATGGCGGCCAAAAGTACGCCCAACTTAATTCCCATGGCTCACCCCATAATG
ATTACTGGTGTGAATATCGACTTTCAGATACTACCACCGGATCGGGTGGAAATCCGTGGCTTGGTCAAGACAGGCGGTAA
AACAGGGGTAGAAATGGAAGCTCTTACGGCTGTTAGCGTGGCAGCACTAACCATTTATGATATGTGCAAAGCAGTTGACA
AGGGAATGATGATTCAAAACATCCGCTTAGTTAGCAAAAGTGGAGGCAAAAGTGGTGACTTTATGCGGGAGGGAGAAAGT
CAATGGGAAAAATAG

Upstream 100 bases:

>100_bases
CAAAATCATTACCAAAGCAATTCGACATAAACCCAGTCAACACCATATGGAAGATGGCTGGAGGGATCGTCGTGTTATGA
GTCAGATAGGGGGATAAATA

Downstream 100 bases:

>100_bases
TAGCTGTTTGCACCAGCCCTAAGAAGGGCATGAGAAAGAAAAATGTTGGCGAAGGCTTATTGGTGATTGAACATGGTATT
GAAGGGGATGCCCACGTAGG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSELTHFDAKGNAWMVDITEKEETHRVAEVRGEVVMAPATLELIQQGGMAKGDVLGVARVAGIMAAKSTPNLIPMAHPIM
ITGVNIDFQILPPDRVEIRGLVKTGGKTGVEMEALTAVSVAALTIYDMCKAVDKGMMIQNIRLVSKSGGKSGDFMREGES
QWEK

Sequences:

>Translated_164_residues
MSELTHFDAKGNAWMVDITEKEETHRVAEVRGEVVMAPATLELIQQGGMAKGDVLGVARVAGIMAAKSTPNLIPMAHPIM
ITGVNIDFQILPPDRVEIRGLVKTGGKTGVEMEALTAVSVAALTIYDMCKAVDKGMMIQNIRLVSKSGGKSGDFMREGES
QWEK
>Mature_163_residues
SELTHFDAKGNAWMVDITEKEETHRVAEVRGEVVMAPATLELIQQGGMAKGDVLGVARVAGIMAAKSTPNLIPMAHPIMI
TGVNIDFQILPPDRVEIRGLVKTGGKTGVEMEALTAVSVAALTIYDMCKAVDKGMMIQNIRLVSKSGGKSGDFMREGESQ
WEK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=160, Percent_Identity=55.625, Blast_Score=168, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.2953020134228, Blast_Score=133, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=50.9554140127389, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=50.6944444444444, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_DESRM (A4J6S4)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113602.1
- ProteinModelPortal:   A4J6S4
- SMR:   A4J6S4
- STRING:   A4J6S4
- GeneID:   4955403
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_2267
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   A4J6S4
- ProtClustDB:   CLSK2537104
- BioCyc:   DRED349161:DRED_2267-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17670; Mature: 17539

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELTHFDAKGNAWMVDITEKEETHRVAEVRGEVVMAPATLELIQQGGMAKGDVLGVARV
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCHHHHHHHH
AGIMAAKSTPNLIPMAHPIMITGVNIDFQILPPDRVEIRGLVKTGGKTGVEMEALTAVSV
HHHHHCCCCCCCCCCCCCEEEEECCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHH
AALTIYDMCKAVDKGMMIQNIRLVSKSGGKSGDFMREGESQWEK
HHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHCCHHHCCC
>Mature Secondary Structure 
SELTHFDAKGNAWMVDITEKEETHRVAEVRGEVVMAPATLELIQQGGMAKGDVLGVARV
CCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCHHHHHHHH
AGIMAAKSTPNLIPMAHPIMITGVNIDFQILPPDRVEIRGLVKTGGKTGVEMEALTAVSV
HHHHHCCCCCCCCCCCCCEEEEECCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHH
AALTIYDMCKAVDKGMMIQNIRLVSKSGGKSGDFMREGESQWEK
HHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA