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The map label for this gene is wcaL [C]

Identifier: 134300046

GI number: 134300046

Start: 2408337

End: 2409521

Strand: Reverse

Name: wcaL [C]

Synonym: Dred_2202

Alternate gene names: 134300046

Gene position: 2409521-2408337 (Counterclockwise)

Preceding gene: 134300047

Following gene: 134300045

Centisome position: 66.78

GC content: 40.76

Gene sequence:

>1185_bases
TTGGGAAGATATACTATTGCAGGGGTGAAACCGTTGACCAAAATAAAAGTTCTGCATGTGGTAAGGCCCGCAGCAGGTGG
TATGAAAAACCACCTGATTAATTTGATTCGCTATACTGATAAAAATAAATTTTCTGTAACGGTAGCCTGTCCACCAGGAA
CATCCATGTGGGATGAATTATATGACATGGGTGTAGATCTTATCCCTATTCCATTGAGAGGGGAACTTTCACCAACCAAA
GACTATTTGGTGGTACATACATTAGTTAAATATTTGCATCAATCCAGAACAACTATTTTGCATACGCATAGTTCTAAGGC
GGCTCTGGTGGGGCGCGTGGCAGGGATCATAGCACGAACTCCAGTGATTATCTTTACTGTTCATAACAGTATTTTTTATG
AAGAATGGTCTCGGTTAAAGAAAAAAATATACTCGACGGTGGAAAAAATATTAGCGAGATTTACAGATCGGATTATTACA
GTTTCCGAGGCATTAAAACAGGAATTATTGGTGAAAGAAGATCTATCACCTACACGATTAACTACCATTTACAATGGAAT
TGAGGTTGAAAAATTCACTACACAAAGTGACCTTAATGAAATAAGACAAAGCTTTAATATTCCTGAATCGAGTATGATCA
TAGGGACAATTGCCCGTCTTGCCCCGCAAAAGGGTGTTAGTTATTTACTTAAGGCAGCTTCCCATCTTAAAGAATATAAT
GTAACTTTTTTAGTGGTGGGGGATGGTCCGCTGCGGCAGGAACTGGAACAAGAAGTCTCTGAGAGAGGGCTGCAAAACAG
GGTAATCTTTGCCGGAAAGCGGGACAATATTCCAGAGATTCTATCAATATTGGATATTTTTGTGTTGCCCTCTGTTACGG
AAGGACTTCCTTTAACCATATTAGAAGCAATGGCCGCGTCTAAACCAGTTGTGGCTACCCGTGTTGGTGGTGTTCCGGAA
GCAATTGTAGAGGGAAAAACCGGTTTGGTAGTGTCACCCAAGGACCCGGAGGCATTGGCAGTTGCTCTGGCAGGGTTGTT
AGGCGAAAGGGATCGGCTAAATCGCATGGGCCAAAACGGGCAAAAACATGCAAGTGAAAAATTCACCGTTAATCTGATGG
TAGAAAAAACAATGGATCTATACAAACAATTATTATTAGAAAAGAAAATTAAAACCCAACGTTAG

Upstream 100 bases:

>100_bases
CAATAGAGGCGGTCTTTTTCTGTGCAAGTTTTCTAATCGACGGGCAGGAGAGTCTACCAAAGGCGGCGAATAATGGTGGG
ATGCATATCGAGGGTTAGGA

Downstream 100 bases:

>100_bases
AATTAAACAAACAAAATTATATAGGTGGGGGGATGGAATTTGCCTTACTCTTTCTGGCAAAAAGTCATTGCCAGTTTATT
ATTTGTATGTGTTACTCTGA

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MGRYTIAGVKPLTKIKVLHVVRPAAGGMKNHLINLIRYTDKNKFSVTVACPPGTSMWDELYDMGVDLIPIPLRGELSPTK
DYLVVHTLVKYLHQSRTTILHTHSSKAALVGRVAGIIARTPVIIFTVHNSIFYEEWSRLKKKIYSTVEKILARFTDRIIT
VSEALKQELLVKEDLSPTRLTTIYNGIEVEKFTTQSDLNEIRQSFNIPESSMIIGTIARLAPQKGVSYLLKAASHLKEYN
VTFLVVGDGPLRQELEQEVSERGLQNRVIFAGKRDNIPEILSILDIFVLPSVTEGLPLTILEAMAASKPVVATRVGGVPE
AIVEGKTGLVVSPKDPEALAVALAGLLGERDRLNRMGQNGQKHASEKFTVNLMVEKTMDLYKQLLLEKKIKTQR

Sequences:

>Translated_394_residues
MGRYTIAGVKPLTKIKVLHVVRPAAGGMKNHLINLIRYTDKNKFSVTVACPPGTSMWDELYDMGVDLIPIPLRGELSPTK
DYLVVHTLVKYLHQSRTTILHTHSSKAALVGRVAGIIARTPVIIFTVHNSIFYEEWSRLKKKIYSTVEKILARFTDRIIT
VSEALKQELLVKEDLSPTRLTTIYNGIEVEKFTTQSDLNEIRQSFNIPESSMIIGTIARLAPQKGVSYLLKAASHLKEYN
VTFLVVGDGPLRQELEQEVSERGLQNRVIFAGKRDNIPEILSILDIFVLPSVTEGLPLTILEAMAASKPVVATRVGGVPE
AIVEGKTGLVVSPKDPEALAVALAGLLGERDRLNRMGQNGQKHASEKFTVNLMVEKTMDLYKQLLLEKKIKTQR
>Mature_393_residues
GRYTIAGVKPLTKIKVLHVVRPAAGGMKNHLINLIRYTDKNKFSVTVACPPGTSMWDELYDMGVDLIPIPLRGELSPTKD
YLVVHTLVKYLHQSRTTILHTHSSKAALVGRVAGIIARTPVIIFTVHNSIFYEEWSRLKKKIYSTVEKILARFTDRIITV
SEALKQELLVKEDLSPTRLTTIYNGIEVEKFTTQSDLNEIRQSFNIPESSMIIGTIARLAPQKGVSYLLKAASHLKEYNV
TFLVVGDGPLRQELEQEVSERGLQNRVIFAGKRDNIPEILSILDIFVLPSVTEGLPLTILEAMAASKPVVATRVGGVPEA
IVEGKTGLVVSPKDPEALAVALAGLLGERDRLNRMGQNGQKHASEKFTVNLMVEKTMDLYKQLLLEKKIKTQR

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=313, Percent_Identity=27.4760383386581, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788357, Length=138, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17532709, Length=279, Percent_Identity=30.1075268817204, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI9755344, Length=174, Percent_Identity=29.8850574712644, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654571, Length=240, Percent_Identity=27.0833333333333, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 43841; Mature: 43710

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRYTIAGVKPLTKIKVLHVVRPAAGGMKNHLINLIRYTDKNKFSVTVACPPGTSMWDEL
CCCEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
YDMGVDLIPIPLRGELSPTKDYLVVHTLVKYLHQSRTTILHTHSSKAALVGRVAGIIART
HHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
PVIIFTVHNSIFYEEWSRLKKKIYSTVEKILARFTDRIITVSEALKQELLVKEDLSPTRL
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
TTIYNGIEVEKFTTQSDLNEIRQSFNIPESSMIIGTIARLAPQKGVSYLLKAASHLKEYN
HHHHCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
VTFLVVGDGPLRQELEQEVSERGLQNRVIFAGKRDNIPEILSILDIFVLPSVTEGLPLTI
EEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHH
LEAMAASKPVVATRVGGVPEAIVEGKTGLVVSPKDPEALAVALAGLLGERDRLNRMGQNG
HHHHHCCCCEEEEECCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHHCCHHHHHHHCCCC
QKHASEKFTVNLMVEKTMDLYKQLLLEKKIKTQR
CHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRYTIAGVKPLTKIKVLHVVRPAAGGMKNHLINLIRYTDKNKFSVTVACPPGTSMWDEL
CCEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
YDMGVDLIPIPLRGELSPTKDYLVVHTLVKYLHQSRTTILHTHSSKAALVGRVAGIIART
HHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
PVIIFTVHNSIFYEEWSRLKKKIYSTVEKILARFTDRIITVSEALKQELLVKEDLSPTRL
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
TTIYNGIEVEKFTTQSDLNEIRQSFNIPESSMIIGTIARLAPQKGVSYLLKAASHLKEYN
HHHHCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
VTFLVVGDGPLRQELEQEVSERGLQNRVIFAGKRDNIPEILSILDIFVLPSVTEGLPLTI
EEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHH
LEAMAASKPVVATRVGGVPEAIVEGKTGLVVSPKDPEALAVALAGLLGERDRLNRMGQNG
HHHHHCCCCEEEEECCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHHCCHHHHHHHCCCC
QKHASEKFTVNLMVEKTMDLYKQLLLEKKIKTQR
CHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]