Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 134299991

GI number: 134299991

Start: 2345138

End: 2348953

Strand: Reverse

Name: luxQ [H]

Synonym: Dred_2145

Alternate gene names: 134299991

Gene position: 2348953-2345138 (Counterclockwise)

Preceding gene: 134299992

Following gene: 134299990

Centisome position: 65.1

GC content: 39.44

Gene sequence:

>3816_bases
GTGAGAGAAAAGCTGGTTGAATTACTCACCCGCAGGGAAGATGATATCATACAACGACTAATTGACTATGCTAAAGCAGG
CGGGTTTACCAGATATAGTTCCACACGCCGAGGAGATTGGCGTCTGTCAGTGCATGAAATCATTCATGCATTGACATATT
ACCTAAAAAGTTATGACAATGATCAAATTTATGTGGAAGAGCAGGTAGGGGAAGATTCAGTAACTCATTTTGGAATAGAA
AGCGCAAAACTGCACCGGGCCAGGGGAATTACCCTAAAGATGTTCTTGGGACTCTTTAAATACTACCGCCGAGCATACTT
GGATATGGTTATTGAAAGCAATTTAACAAACCAGGAGAAAAAACAAGCTGAAGAAGCAATGAATACCTTTTTTGATCGTT
TTGAGATCGGTTTTTGCAGTGAATGGGTAGGTGAAGGACCGGAATCAAGACTTGCTGAATTGCAGTCAATTAATAGAAAG
TTAACCAATGAGAAAAATAAATTATGGACTATCTTTGAAAGTATGACGGAGTGTGTCTTTGTCGTTGACTCTAATATGAA
GATCACTGAAATAAATGCTGCAGCTGCAGCTTATTTTCAAGTCAACCCAGAGGAGGTATTGGGCCTAAACTGTTCTGAGT
TAATGGGTTGTGAATGTAGAGAAGAGGATTGTCATCTTTTTCATGCTATGAAAAGTGGCGGTTGTTATAAAGATGTGGAA
CTGGAAATTAAGACACAAAAAGGGCGAAGGCGTATCTTAACCAGTGGTTCTTTTCTTCATGATATTAGTGGAAAATATGC
CGGAGGGGTTCAGGTTTTTGCCGATATTACAGAGCGCAATCTAATGGAACAATCCCTTCGTTTACACATGCATGCCAATA
ATAGTTCCGTTGAATCTGTCAGTATATTTGACATTGGCGGTAATTTAACCTATGCCAACCCTGCGGCGGAAGATTTGTTT
GGTATGGATGGTAGCCAGTTGCTGGGCCTGGGCATTGAACAGGCCTACCAGGGTGGGGAAATGGTACTTTTATCTTTAAT
TCGTGGTAAATCCTGGAAGGGAGAAGTGAGCCAGAACGGCAAGATACTATATATTCATGCCAATCCCATAAGATTACCCA
AGGGGAATATTATCGGTTTTTATGTTTCTGCCAGAGATATTACCGCCCATAAGGCAACCCAGTTAAAATTACAGCAGGCC
AGAGAAGAGACCGAAAGGGAAGCTGCCAAACTAAGAGCAATTATCTCTATAATGAATGCGGCCATTGCACTGGTGGATGC
AGAGGGTATTATTACTGAAATAAATGAACAATGCCTGACTATAACAGGAAAAGTCAGAGAGGACCTGATTGGCAAGAAGC
TTGAGAGTCTCCACAACGGTAAAATCCTTGAAAAAATTCAGAAGATGATTGCAAATTTTCGCCTCAACCGTAATTCTTCT
CCGGTCACCATAACACGGAGGGTTGGGGGAATGGATGTTATTATGAACATCCAGCCGGTTTACCGTGATAAAACATACGA
TGGTGTATTATTGATGGTGGTGGATGTAACGGAAGTGGCTAAGGCCAAAAGGCAGGCTGAACAGGCCCTTCTAGTGGCGG
AAAAGGCCAGCAAAGCGAAATCAGAATTCTTGGCCAACATGAGTCATGAGATAAGGACTCCCATGAATGGTATCCTGGGA
TTTGCAGAGGTGTTAATACAACAAGAATTAAGTCCCCAACAACAGGAAAGTGTTAAAATCATCCAACAATGTGGCGAGCA
ACTAATGGATCTCATTAATGATATTTTAGATCTCTCTAAAATAGAGTCGGGTAAATTAGTTATGGAAGAAACGAGTTTTA
GTTTGCGCAAACTGATCCATGAGGCAGTTAATGTGATTGAAAGCAAATTTTTGGAGCAAAATGTAGAAATGAAGATTGAT
ATAGAACAAAATCTTCATGATCAGCTTAAAGGAGATCCCACCCGGATAAGACAGGTTTTATACAACCTAATTTCCAATGC
GGCGAAATTTACTCATCAAGGATATGTGAAAATTTCAGTGGCAGAGGAATCAATAAGTGGTGCTGATCACCAAATAAAGT
TAAGGTTTTGTATAGAAGATACAGGAATAGGGATACCTAAGGAAAAGTTAAAGTTAATTTTTGATGCCTTTACCCAAGCA
GATGGTTCCACAACCCGTAAGTACGGGGGTACAGGTCTGGGTTTAACCATATGTAAAAGCCTTACCCAATTAATGGGTGG
AGAGATAAATGTAGAAAGTCAAGTAAACAAAGGTTCAATCTTCTCTTTCTATATTCCTGTCAACAAGGTTGAAATAAGTG
AAGAAGAAAAGTTAATGGAATCAGAAATGATGCAGGGCAAAAATGGAACTGTTTTGGTGGTAGAGGATGATTGGACTACA
AAGCAATTGATTTCGAACTATTTGGAAAAGGTAGGCTATTCGGTAATAACTACCCAACAAGGAAAACAGGCCATAACCTT
AGCCAAAATATATCGACCAGATGTAATGATTCTTGATATTTTGTTGCCTGATCTAACAGGTTGGGAAATTCTAAAAAGGA
TTAAAACCTATGAAGAAACTAAGGATATTCCCATTGTTGTATGTTCTGTGATGCCAGAAAAAGAACAGGCCTTTTCTCTG
GGAGCGGTGGATTTCATTGAAAAGCCTATTTCAGAAAAAGTATTAATTTCTCGTTTAGGAAAACTCATCTCGGGCAAAAA
AAAGGATGATACTCATATTGTATTGATTGATGATGAAGAAGCTACTTTGCAATTCCTGAAGAAGATAATAGAAAATGAAG
GATATAGAACGCACACCTTTGCTAGGGCAGGGGACGCATTTTATTACCTAATGCAAGGTGGTGCAGTCCATGCAATACTA
TTAGATCTCTTAATGCCGGGTATGAATGGCTTCGAATTTTTGGAAAGCCTGCGGCTGAAGCCAGAGTTTAGGGACATACC
TGTAATAATCAATACAGCAAAGGATCTAACTCAGAAAGATTATCAAAAACTAAACCTTAAGTGTGAGAAGATATTAAACA
AGAGTTTAGTACATCCCCATGATTTGTTAGAAGAATTATCGGAAATTCTAAAGGGGGTTACTGGTTGTTCAAAGACTCAA
GGGGGAATTGAGCGGATTAAGATACTATTGGTTGAGGATAACCACTTTAATCAACGATTGGTGACACATATGCTGTCTGA
TGATTATTCAATAGTGGAGGTCGAGAATGGTGTGCAGGCCTTGGAGATACTGGAAGAGCAAAAATTTGACCTAGTATTAA
TGGATATGCAAATGCCAGTGATGGATGGCTATGAAACCACTCGTCTGATTCGCAAACAAAATAAATATAAGAATTTACCC
ATTATTGCTCTAACAGCCTATGCTATGAAAGGGGACTCGGAAAAATGTATGGCAGCGGGATGCAACGGTTATCTTGCAAA
ACCCGTTAAGCGAGACCAATTAATAAAAACGATAAAACAGCAGTTTGTTTTATCAACTGGTACTCCTCAAAAAATTAGAA
TTAGAGATAAAGGAATAGAATCTCTGGTTCCCTGGTACCTACAGGATATAGGGAGGGAAATGGAAAAATTAAAGAATGCT
GCGAAAATATGTGATTTTAATGCAGTTCGTTATATTGGGCATGGCTTAAAGGGTTCAGGAGGAGCTTATGGTTTCCCAGA
GTTTTCGGCCAGTGGGGCGGAAATTGAACGTGCTGCTCTGGATGAAGATGTGGTCTTAGTAAAAATGAGGGTCAATCAAT
TACGAGAGTTATATACAAAGGTACTGGAAGAGGAACTTTCAAATACGAAAGAATAG

Upstream 100 bases:

>100_bases
CGAAAAAATTTAATTCTTTTGTAAGGTTTAAGTTAAATAAAAACAAGATTATTTTGTTATTATCCAACTACATACTTGAT
TATCAATGGGAGGTCATGGC

Downstream 100 bases:

>100_bases
CATAGGGGAGATCTTCTTAGGGATAAAATGTCGTAAAAAAAGCAATCCCGTACCACTTTGAAAGTGGTACGGGATTGCTT
TTTGGGAATTTATTTAATCT

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1271; Mature: 1271

Protein sequence:

>1271_residues
MREKLVELLTRREDDIIQRLIDYAKAGGFTRYSSTRRGDWRLSVHEIIHALTYYLKSYDNDQIYVEEQVGEDSVTHFGIE
SAKLHRARGITLKMFLGLFKYYRRAYLDMVIESNLTNQEKKQAEEAMNTFFDRFEIGFCSEWVGEGPESRLAELQSINRK
LTNEKNKLWTIFESMTECVFVVDSNMKITEINAAAAAYFQVNPEEVLGLNCSELMGCECREEDCHLFHAMKSGGCYKDVE
LEIKTQKGRRRILTSGSFLHDISGKYAGGVQVFADITERNLMEQSLRLHMHANNSSVESVSIFDIGGNLTYANPAAEDLF
GMDGSQLLGLGIEQAYQGGEMVLLSLIRGKSWKGEVSQNGKILYIHANPIRLPKGNIIGFYVSARDITAHKATQLKLQQA
REETEREAAKLRAIISIMNAAIALVDAEGIITEINEQCLTITGKVREDLIGKKLESLHNGKILEKIQKMIANFRLNRNSS
PVTITRRVGGMDVIMNIQPVYRDKTYDGVLLMVVDVTEVAKAKRQAEQALLVAEKASKAKSEFLANMSHEIRTPMNGILG
FAEVLIQQELSPQQQESVKIIQQCGEQLMDLINDILDLSKIESGKLVMEETSFSLRKLIHEAVNVIESKFLEQNVEMKID
IEQNLHDQLKGDPTRIRQVLYNLISNAAKFTHQGYVKISVAEESISGADHQIKLRFCIEDTGIGIPKEKLKLIFDAFTQA
DGSTTRKYGGTGLGLTICKSLTQLMGGEINVESQVNKGSIFSFYIPVNKVEISEEEKLMESEMMQGKNGTVLVVEDDWTT
KQLISNYLEKVGYSVITTQQGKQAITLAKIYRPDVMILDILLPDLTGWEILKRIKTYEETKDIPIVVCSVMPEKEQAFSL
GAVDFIEKPISEKVLISRLGKLISGKKKDDTHIVLIDDEEATLQFLKKIIENEGYRTHTFARAGDAFYYLMQGGAVHAIL
LDLLMPGMNGFEFLESLRLKPEFRDIPVIINTAKDLTQKDYQKLNLKCEKILNKSLVHPHDLLEELSEILKGVTGCSKTQ
GGIERIKILLVEDNHFNQRLVTHMLSDDYSIVEVENGVQALEILEEQKFDLVLMDMQMPVMDGYETTRLIRKQNKYKNLP
IIALTAYAMKGDSEKCMAAGCNGYLAKPVKRDQLIKTIKQQFVLSTGTPQKIRIRDKGIESLVPWYLQDIGREMEKLKNA
AKICDFNAVRYIGHGLKGSGGAYGFPEFSASGAEIERAALDEDVVLVKMRVNQLRELYTKVLEEELSNTKE

Sequences:

>Translated_1271_residues
MREKLVELLTRREDDIIQRLIDYAKAGGFTRYSSTRRGDWRLSVHEIIHALTYYLKSYDNDQIYVEEQVGEDSVTHFGIE
SAKLHRARGITLKMFLGLFKYYRRAYLDMVIESNLTNQEKKQAEEAMNTFFDRFEIGFCSEWVGEGPESRLAELQSINRK
LTNEKNKLWTIFESMTECVFVVDSNMKITEINAAAAAYFQVNPEEVLGLNCSELMGCECREEDCHLFHAMKSGGCYKDVE
LEIKTQKGRRRILTSGSFLHDISGKYAGGVQVFADITERNLMEQSLRLHMHANNSSVESVSIFDIGGNLTYANPAAEDLF
GMDGSQLLGLGIEQAYQGGEMVLLSLIRGKSWKGEVSQNGKILYIHANPIRLPKGNIIGFYVSARDITAHKATQLKLQQA
REETEREAAKLRAIISIMNAAIALVDAEGIITEINEQCLTITGKVREDLIGKKLESLHNGKILEKIQKMIANFRLNRNSS
PVTITRRVGGMDVIMNIQPVYRDKTYDGVLLMVVDVTEVAKAKRQAEQALLVAEKASKAKSEFLANMSHEIRTPMNGILG
FAEVLIQQELSPQQQESVKIIQQCGEQLMDLINDILDLSKIESGKLVMEETSFSLRKLIHEAVNVIESKFLEQNVEMKID
IEQNLHDQLKGDPTRIRQVLYNLISNAAKFTHQGYVKISVAEESISGADHQIKLRFCIEDTGIGIPKEKLKLIFDAFTQA
DGSTTRKYGGTGLGLTICKSLTQLMGGEINVESQVNKGSIFSFYIPVNKVEISEEEKLMESEMMQGKNGTVLVVEDDWTT
KQLISNYLEKVGYSVITTQQGKQAITLAKIYRPDVMILDILLPDLTGWEILKRIKTYEETKDIPIVVCSVMPEKEQAFSL
GAVDFIEKPISEKVLISRLGKLISGKKKDDTHIVLIDDEEATLQFLKKIIENEGYRTHTFARAGDAFYYLMQGGAVHAIL
LDLLMPGMNGFEFLESLRLKPEFRDIPVIINTAKDLTQKDYQKLNLKCEKILNKSLVHPHDLLEELSEILKGVTGCSKTQ
GGIERIKILLVEDNHFNQRLVTHMLSDDYSIVEVENGVQALEILEEQKFDLVLMDMQMPVMDGYETTRLIRKQNKYKNLP
IIALTAYAMKGDSEKCMAAGCNGYLAKPVKRDQLIKTIKQQFVLSTGTPQKIRIRDKGIESLVPWYLQDIGREMEKLKNA
AKICDFNAVRYIGHGLKGSGGAYGFPEFSASGAEIERAALDEDVVLVKMRVNQLRELYTKVLEEELSNTKE
>Mature_1271_residues
MREKLVELLTRREDDIIQRLIDYAKAGGFTRYSSTRRGDWRLSVHEIIHALTYYLKSYDNDQIYVEEQVGEDSVTHFGIE
SAKLHRARGITLKMFLGLFKYYRRAYLDMVIESNLTNQEKKQAEEAMNTFFDRFEIGFCSEWVGEGPESRLAELQSINRK
LTNEKNKLWTIFESMTECVFVVDSNMKITEINAAAAAYFQVNPEEVLGLNCSELMGCECREEDCHLFHAMKSGGCYKDVE
LEIKTQKGRRRILTSGSFLHDISGKYAGGVQVFADITERNLMEQSLRLHMHANNSSVESVSIFDIGGNLTYANPAAEDLF
GMDGSQLLGLGIEQAYQGGEMVLLSLIRGKSWKGEVSQNGKILYIHANPIRLPKGNIIGFYVSARDITAHKATQLKLQQA
REETEREAAKLRAIISIMNAAIALVDAEGIITEINEQCLTITGKVREDLIGKKLESLHNGKILEKIQKMIANFRLNRNSS
PVTITRRVGGMDVIMNIQPVYRDKTYDGVLLMVVDVTEVAKAKRQAEQALLVAEKASKAKSEFLANMSHEIRTPMNGILG
FAEVLIQQELSPQQQESVKIIQQCGEQLMDLINDILDLSKIESGKLVMEETSFSLRKLIHEAVNVIESKFLEQNVEMKID
IEQNLHDQLKGDPTRIRQVLYNLISNAAKFTHQGYVKISVAEESISGADHQIKLRFCIEDTGIGIPKEKLKLIFDAFTQA
DGSTTRKYGGTGLGLTICKSLTQLMGGEINVESQVNKGSIFSFYIPVNKVEISEEEKLMESEMMQGKNGTVLVVEDDWTT
KQLISNYLEKVGYSVITTQQGKQAITLAKIYRPDVMILDILLPDLTGWEILKRIKTYEETKDIPIVVCSVMPEKEQAFSL
GAVDFIEKPISEKVLISRLGKLISGKKKDDTHIVLIDDEEATLQFLKKIIENEGYRTHTFARAGDAFYYLMQGGAVHAIL
LDLLMPGMNGFEFLESLRLKPEFRDIPVIINTAKDLTQKDYQKLNLKCEKILNKSLVHPHDLLEELSEILKGVTGCSKTQ
GGIERIKILLVEDNHFNQRLVTHMLSDDYSIVEVENGVQALEILEEQKFDLVLMDMQMPVMDGYETTRLIRKQNKYKNLP
IIALTAYAMKGDSEKCMAAGCNGYLAKPVKRDQLIKTIKQQFVLSTGTPQKIRIRDKGIESLVPWYLQDIGREMEKLKNA
AKICDFNAVRYIGHGLKGSGGAYGFPEFSASGAEIERAALDEDVVLVKMRVNQLRELYTKVLEEELSNTKE

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=480, Percent_Identity=31.6666666666667, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI48994928, Length=547, Percent_Identity=29.981718464351, Blast_Score=206, Evalue=9e-54,
Organism=Escherichia coli, GI145693157, Length=527, Percent_Identity=29.6015180265655, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1788713, Length=419, Percent_Identity=30.7875894988067, Blast_Score=180, Evalue=5e-46,
Organism=Escherichia coli, GI87081816, Length=330, Percent_Identity=33.9393939393939, Blast_Score=180, Evalue=5e-46,
Organism=Escherichia coli, GI1788549, Length=383, Percent_Identity=25.8485639686684, Blast_Score=104, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=257, Percent_Identity=29.5719844357977, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786912, Length=259, Percent_Identity=27.027027027027, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=25.6916996047431, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=28.82096069869, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=27.8969957081545, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1790300, Length=279, Percent_Identity=26.1648745519713, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=23.7704918032787, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1788279, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=33.0508474576271, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=237, Percent_Identity=27.8481012658228, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786599, Length=112, Percent_Identity=31.25, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=239, Percent_Identity=24.6861924686192, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=125, Percent_Identity=39.2, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323034, Length=145, Percent_Identity=32.4137931034483, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=136, Percent_Identity=34.5588235294118, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 143482; Mature: 143482

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREKLVELLTRREDDIIQRLIDYAKAGGFTRYSSTRRGDWRLSVHEIIHALTYYLKSYDN
CHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHCCCC
DQIYVEEQVGEDSVTHFGIESAKLHRARGITLKMFLGLFKYYRRAYLDMVIESNLTNQEK
CEEEEECCCCCCCHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KQAEEAMNTFFDRFEIGFCSEWVGEGPESRLAELQSINRKLTNEKNKLWTIFESMTECVF
HHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEE
VVDSNMKITEINAAAAAYFQVNPEEVLGLNCSELMGCECREEDCHLFHAMKSGGCYKDVE
EEECCEEEEEECHHEEEEEECCHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCCEEEEE
LEIKTQKGRRRILTSGSFLHDISGKYAGGVQVFADITERNLMEQSLRLHMHANNSSVESV
EEEEECCCCHHEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEE
SIFDIGGNLTYANPAAEDLFGMDGSQLLGLGIEQAYQGGEMVLLSLIRGKSWKGEVSQNG
EEEEECCCEEECCCCHHHHHCCCCCHHHHCCHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
KILYIHANPIRLPKGNIIGFYVSARDITAHKATQLKLQQAREETEREAAKLRAIISIMNA
EEEEEECCCEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIALVDAEGIITEINEQCLTITGKVREDLIGKKLESLHNGKILEKIQKMIANFRLNRNSS
HHHEEECCHHHHHHCCHHEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PVTITRRVGGMDVIMNIQPVYRDKTYDGVLLMVVDVTEVAKAKRQAEQALLVAEKASKAK
CEEEEEECCCEEEEEECCHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SEFLANMSHEIRTPMNGILGFAEVLIQQELSPQQQESVKIIQQCGEQLMDLINDILDLSK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IESGKLVMEETSFSLRKLIHEAVNVIESKFLEQNVEMKIDIEQNLHDQLKGDPTRIRQVL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHHHHHCCCHHHHHHHH
YNLISNAAKFTHQGYVKISVAEESISGADHQIKLRFCIEDTGIGIPKEKLKLIFDAFTQA
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCC
DGSTTRKYGGTGLGLTICKSLTQLMGGEINVESQVNKGSIFSFYIPVNKVEISEEEKLME
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEECCEEECCHHHHHHH
SEMMQGKNGTVLVVEDDWTTKQLISNYLEKVGYSVITTQQGKQAITLAKIYRPDVMILDI
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHHCCCEEEEEH
LLPDLTGWEILKRIKTYEETKDIPIVVCSVMPEKEQAFSLGAVDFIEKPISEKVLISRLG
HCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCHHHHHHCCHHHHHHHHHHH
KLISGKKKDDTHIVLIDDEEATLQFLKKIIENEGYRTHTFARAGDAFYYLMQGGAVHAIL
HHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEHHHCCCEEEEEECCCHHHHHH
LDLLMPGMNGFEFLESLRLKPEFRDIPVIINTAKDLTQKDYQKLNLKCEKILNKSLVHPH
HHHHHCCCCHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCHH
DLLEELSEILKGVTGCSKTQGGIERIKILLVEDNHFNQRLVTHMLSDDYSIVEVENGVQA
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHH
LEILEEQKFDLVLMDMQMPVMDGYETTRLIRKQNKYKNLPIIALTAYAMKGDSEKCMAAG
HHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHCC
CNGYLAKPVKRDQLIKTIKQQFVLSTGTPQKIRIRDKGIESLVPWYLQDIGREMEKLKNA
CCCCCCCCCCHHHHHHHHHHHHEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AKICDFNAVRYIGHGLKGSGGAYGFPEFSASGAEIERAALDEDVVLVKMRVNQLRELYTK
HHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHH
VLEEELSNTKE
HHHHHHHCCCC
>Mature Secondary Structure
MREKLVELLTRREDDIIQRLIDYAKAGGFTRYSSTRRGDWRLSVHEIIHALTYYLKSYDN
CHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHCCCC
DQIYVEEQVGEDSVTHFGIESAKLHRARGITLKMFLGLFKYYRRAYLDMVIESNLTNQEK
CEEEEECCCCCCCHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KQAEEAMNTFFDRFEIGFCSEWVGEGPESRLAELQSINRKLTNEKNKLWTIFESMTECVF
HHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEE
VVDSNMKITEINAAAAAYFQVNPEEVLGLNCSELMGCECREEDCHLFHAMKSGGCYKDVE
EEECCEEEEEECHHEEEEEECCHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCCEEEEE
LEIKTQKGRRRILTSGSFLHDISGKYAGGVQVFADITERNLMEQSLRLHMHANNSSVESV
EEEEECCCCHHEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEE
SIFDIGGNLTYANPAAEDLFGMDGSQLLGLGIEQAYQGGEMVLLSLIRGKSWKGEVSQNG
EEEEECCCEEECCCCHHHHHCCCCCHHHHCCHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
KILYIHANPIRLPKGNIIGFYVSARDITAHKATQLKLQQAREETEREAAKLRAIISIMNA
EEEEEECCCEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIALVDAEGIITEINEQCLTITGKVREDLIGKKLESLHNGKILEKIQKMIANFRLNRNSS
HHHEEECCHHHHHHCCHHEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PVTITRRVGGMDVIMNIQPVYRDKTYDGVLLMVVDVTEVAKAKRQAEQALLVAEKASKAK
CEEEEEECCCEEEEEECCHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SEFLANMSHEIRTPMNGILGFAEVLIQQELSPQQQESVKIIQQCGEQLMDLINDILDLSK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IESGKLVMEETSFSLRKLIHEAVNVIESKFLEQNVEMKIDIEQNLHDQLKGDPTRIRQVL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHHHHHCCCHHHHHHHH
YNLISNAAKFTHQGYVKISVAEESISGADHQIKLRFCIEDTGIGIPKEKLKLIFDAFTQA
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCC
DGSTTRKYGGTGLGLTICKSLTQLMGGEINVESQVNKGSIFSFYIPVNKVEISEEEKLME
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEECCEEECCHHHHHHH
SEMMQGKNGTVLVVEDDWTTKQLISNYLEKVGYSVITTQQGKQAITLAKIYRPDVMILDI
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHHCCCEEEEEH
LLPDLTGWEILKRIKTYEETKDIPIVVCSVMPEKEQAFSLGAVDFIEKPISEKVLISRLG
HCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCHHHHHHCCHHHHHHHHHHH
KLISGKKKDDTHIVLIDDEEATLQFLKKIIENEGYRTHTFARAGDAFYYLMQGGAVHAIL
HHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEHHHCCCEEEEEECCCHHHHHH
LDLLMPGMNGFEFLESLRLKPEFRDIPVIINTAKDLTQKDYQKLNLKCEKILNKSLVHPH
HHHHHCCCCHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCHH
DLLEELSEILKGVTGCSKTQGGIERIKILLVEDNHFNQRLVTHMLSDDYSIVEVENGVQA
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHH
LEILEEQKFDLVLMDMQMPVMDGYETTRLIRKQNKYKNLPIIALTAYAMKGDSEKCMAAG
HHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHCC
CNGYLAKPVKRDQLIKTIKQQFVLSTGTPQKIRIRDKGIESLVPWYLQDIGREMEKLKNA
CCCCCCCCCCHHHHHHHHHHHHEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AKICDFNAVRYIGHGLKGSGGAYGFPEFSASGAEIERAALDEDVVLVKMRVNQLRELYTK
HHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHH
VLEEELSNTKE
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA