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The map label for this gene is codY [H]

Identifier: 134299826

GI number: 134299826

Start: 2172945

End: 2173730

Strand: Reverse

Name: codY [H]

Synonym: Dred_1979

Alternate gene names: 134299826

Gene position: 2173730-2172945 (Counterclockwise)

Preceding gene: 134299827

Following gene: 134299825

Centisome position: 60.25

GC content: 42.62

Gene sequence:

>786_bases
ATGAAGACCTTATTGGAAAGAACACGTACAATTAATAAACTATTACAGAAATCTGCTGGTTATCCTGTTGACTTTGGCGA
AATCGCAGATGTGTTATCTGAGAACATTGAGGCAAACTGCTATATTATTGACCGTCGTGGTCGGGCCCTTGGCTACAAAT
TTATGCCAGAGTTTGCCTGTGATATTATGAAAGATATTGTTGAAGGTTCCAAACGTTTTCCTGAGGAATACAACGAAGGA
CTTTTGGGAGTTAGTGAAACCCATGCAAACTTCTGCCAGACCTATGATGCATGTGTATTCTTTGAGGAAGAAAAGTGTAA
GGGTCAAAACAAAGTTACCACTGTGGTTCCCATTGTAGGTGCTGGTTCACGTTTAGGAACCTTGGTGTTGGCTAAGTTTA
ACCAAAACTTTACTGATGAGGACTTGATCTTGGCCGAATATGGTGCCACGGTAGTTGCTATGGAAATTCTACGTGCAAGG
GCAGGAAGAATGGAAGAAGAAGCAAGGAAGAAAGCAGCTGTACAAATTGCCCTCGGTACCTTATCTTACTCTGAATTAGA
TGCAGTTCAACACATTTTTGAACAATTGGAAGGGGACGAGGGGGTCCTGGTTGCCAGCAAGATTGCTGATAGGGTGGGTA
TCACGCGGTCAGTTATTGTAAATGCATTGCGTAAATTTGAAAGCGCTGGGGTGATTGAGTCCAAATCCTTGGGAATGAAG
GGTACTTACATTCGGGTGTTAAACGATCGTTTGATCGAGGAACTGCAAAGGCTGAAGCACAATTAA

Upstream 100 bases:

>100_bases
CACTATTGACAGTGATTATGTTCGTGAGAAGCTAAAGGATGTTGTAACAAATCGTGATCTTAGTCGTTATATTCTTTAAA
AAAACGGGGAGAGTGACAGA

Downstream 100 bases:

>100_bases
AGTAATAAAAACCACAGTTTCAAGCAAACTGTGGTTTTTATTACGGAATAATTGCTTGCGCAGGTTGTCTGATTATGCTA
AAATAACATCTGGTGTTGAA

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKTLLERTRTINKLLQKSAGYPVDFGEIADVLSENIEANCYIIDRRGRALGYKFMPEFACDIMKDIVEGSKRFPEEYNEG
LLGVSETHANFCQTYDACVFFEEEKCKGQNKVTTVVPIVGAGSRLGTLVLAKFNQNFTDEDLILAEYGATVVAMEILRAR
AGRMEEEARKKAAVQIALGTLSYSELDAVQHIFEQLEGDEGVLVASKIADRVGITRSVIVNALRKFESAGVIESKSLGMK
GTYIRVLNDRLIEELQRLKHN

Sequences:

>Translated_261_residues
MKTLLERTRTINKLLQKSAGYPVDFGEIADVLSENIEANCYIIDRRGRALGYKFMPEFACDIMKDIVEGSKRFPEEYNEG
LLGVSETHANFCQTYDACVFFEEEKCKGQNKVTTVVPIVGAGSRLGTLVLAKFNQNFTDEDLILAEYGATVVAMEILRAR
AGRMEEEARKKAAVQIALGTLSYSELDAVQHIFEQLEGDEGVLVASKIADRVGITRSVIVNALRKFESAGVIESKSLGMK
GTYIRVLNDRLIEELQRLKHN
>Mature_261_residues
MKTLLERTRTINKLLQKSAGYPVDFGEIADVLSENIEANCYIIDRRGRALGYKFMPEFACDIMKDIVEGSKRFPEEYNEG
LLGVSETHANFCQTYDACVFFEEEKCKGQNKVTTVVPIVGAGSRLGTLVLAKFNQNFTDEDLILAEYGATVVAMEILRAR
AGRMEEEARKKAAVQIALGTLSYSELDAVQHIFEQLEGDEGVLVASKIADRVGITRSVIVNALRKFESAGVIESKSLGMK
GTYIRVLNDRLIEELQRLKHN

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991 [H]

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY [H]

EC number: NA

Molecular weight: Translated: 29110; Mature: 29110

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLLERTRTINKLLQKSAGYPVDFGEIADVLSENIEANCYIIDRRGRALGYKFMPEFAC
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
DIMKDIVEGSKRFPEEYNEGLLGVSETHANFCQTYDACVFFEEEKCKGQNKVTTVVPIVG
HHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHEEEEHHHCCCCCCEEEEEEEEC
AGSRLGTLVLAKFNQNFTDEDLILAEYGATVVAMEILRARAGRMEEEARKKAAVQIALGT
CCCHHHHHHHEECCCCCCCCCEEHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSYSELDAVQHIFEQLEGDEGVLVASKIADRVGITRSVIVNALRKFESAGVIESKSLGMK
CCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCCCCC
GTYIRVLNDRLIEELQRLKHN
CHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLLERTRTINKLLQKSAGYPVDFGEIADVLSENIEANCYIIDRRGRALGYKFMPEFAC
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
DIMKDIVEGSKRFPEEYNEGLLGVSETHANFCQTYDACVFFEEEKCKGQNKVTTVVPIVG
HHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHEEEEHHHCCCCCCEEEEEEEEC
AGSRLGTLVLAKFNQNFTDEDLILAEYGATVVAMEILRARAGRMEEEARKKAAVQIALGT
CCCHHHHHHHEECCCCCCCCCEEHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSYSELDAVQHIFEQLEGDEGVLVASKIADRVGITRSVIVNALRKFESAGVIESKSLGMK
CCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCCCCC
GTYIRVLNDRLIEELQRLKHN
CHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA