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The map label for this gene is tsf

Identifier: 134299824

GI number: 134299824

Start: 2171263

End: 2171916

Strand: Reverse

Name: tsf

Synonym: Dred_1977

Alternate gene names: 134299824

Gene position: 2171916-2171263 (Counterclockwise)

Preceding gene: 134299825

Following gene: 134299823

Centisome position: 60.2

GC content: 41.44

Gene sequence:

>654_bases
ATGGCAGAAATTTCTGCAAGCATGGTTAAAGAGTTAAGAGAACGTACTGGTGCAGGTATGATGGATTGTAAAAAGGCTTT
AGCTGAAGTGGGCGGGGATATGGAAAAGGCCATTGAGTTTTTGCGTGAAAAGGGTCTTGCTGCTGCTGCTAAAAAAGCTG
GTAGAATTGCCGCTGAAGGTGTTGTGGAATCCTACATACATGGTGGCGGTCGTATCGGTGTTTTGGTTGAAATCAACTGT
GAAACTGATTTTGTTGCTAAAAACGAAGATTTTCGCGGTTTAGCCAAAGACATTGCTATGCAAATCGCGGCTGCTAAACC
TGAGTTCGTGCGCCGGGAGGAAGTTTCTGCAGATAAGATTGAAAAAGAAAAAGAAATCTTAAGAGCACAGGCGTTAAATG
AAGGCAAACCAGAAAAAATTGTCGAAAAAATGGTTGAAGGGCGTATTGAGAAATTCTACAAAGAAGTTTGCCTGCTTGAG
CAACCCTTTATTAAAGATTCTGACAAAACAGTGCAGCAAGTTATTAACGAAATCATTGCCAAGATCGGCGAAAAAGTTGA
TGTTCGTCGTTTTGTCCGTTATGAAATGGGAGAAGGCTTAGAAAAGCGTCAAGATGACTTTGCTGCCGAAGTAGCTGCAC
AAATTAAAGCATAA

Upstream 100 bases:

>100_bases
GTACGGGAGGCCTCTACCTTTTTTTATGTTTGTCAAGGGAAGAATCTGGTTATAATACCACAAGATTAAATGGGTGGTTA
CATAAAGGGGGATTTTGATC

Downstream 100 bases:

>100_bases
TATTTATTTGATAACGTTTAAAAGGATTTTTTAAAAAGTTGTAGAATAACAGAACTACCAGACTGGAGGACACCCTTAAT
GGTAACTCCCAAGTTTAGGC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAEISASMVKELRERTGAGMMDCKKALAEVGGDMEKAIEFLREKGLAAAAKKAGRIAAEGVVESYIHGGGRIGVLVEINC
ETDFVAKNEDFRGLAKDIAMQIAAAKPEFVRREEVSADKIEKEKEILRAQALNEGKPEKIVEKMVEGRIEKFYKEVCLLE
QPFIKDSDKTVQQVINEIIAKIGEKVDVRRFVRYEMGEGLEKRQDDFAAEVAAQIKA

Sequences:

>Translated_217_residues
MAEISASMVKELRERTGAGMMDCKKALAEVGGDMEKAIEFLREKGLAAAAKKAGRIAAEGVVESYIHGGGRIGVLVEINC
ETDFVAKNEDFRGLAKDIAMQIAAAKPEFVRREEVSADKIEKEKEILRAQALNEGKPEKIVEKMVEGRIEKFYKEVCLLE
QPFIKDSDKTVQQVINEIIAKIGEKVDVRRFVRYEMGEGLEKRQDDFAAEVAAQIKA
>Mature_216_residues
AEISASMVKELRERTGAGMMDCKKALAEVGGDMEKAIEFLREKGLAAAAKKAGRIAAEGVVESYIHGGGRIGVLVEINCE
TDFVAKNEDFRGLAKDIAMQIAAAKPEFVRREEVSADKIEKEKEILRAQALNEGKPEKIVEKMVEGRIEKFYKEVCLLEQ
PFIKDSDKTVQQVINEIIAKIGEKVDVRRFVRYEMGEGLEKRQDDFAAEVAAQIKA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI291084498, Length=100, Percent_Identity=39, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI291084502, Length=100, Percent_Identity=39, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI291084500, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI171846268, Length=136, Percent_Identity=33.0882352941176, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786366, Length=164, Percent_Identity=48.780487804878, Blast_Score=125, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17561440, Length=195, Percent_Identity=28.7179487179487, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_DESRM (A4J5Z2)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113320.1
- ProteinModelPortal:   A4J5Z2
- SMR:   A4J5Z2
- STRING:   A4J5Z2
- GeneID:   4958358
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_1977
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   NVEYVSI
- PhylomeDB:   A4J5Z2
- ProtClustDB:   PRK12332
- BioCyc:   DRED349161:DRED_1977-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 24122; Mature: 23991

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEISASMVKELRERTGAGMMDCKKALAEVGGDMEKAIEFLREKGLAAAAKKAGRIAAEG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
VVESYIHGGGRIGVLVEINCETDFVAKNEDFRGLAKDIAMQIAAAKPEFVRREEVSADKI
HHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
EKEKEILRAQALNEGKPEKIVEKMVEGRIEKFYKEVCLLEQPFIKDSDKTVQQVINEIIA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KIGEKVDVRRFVRYEMGEGLEKRQDDFAAEVAAQIKA
HHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEISASMVKELRERTGAGMMDCKKALAEVGGDMEKAIEFLREKGLAAAAKKAGRIAAEG
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
VVESYIHGGGRIGVLVEINCETDFVAKNEDFRGLAKDIAMQIAAAKPEFVRREEVSADKI
HHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
EKEKEILRAQALNEGKPEKIVEKMVEGRIEKFYKEVCLLEQPFIKDSDKTVQQVINEIIA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KIGEKVDVRRFVRYEMGEGLEKRQDDFAAEVAAQIKA
HHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA