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The map label for this gene is dapB [H]

Identifier: 134299792

GI number: 134299792

Start: 2135361

End: 2136158

Strand: Reverse

Name: dapB [H]

Synonym: Dred_1944

Alternate gene names: 134299792

Gene position: 2136158-2135361 (Counterclockwise)

Preceding gene: 134299793

Following gene: 134299791

Centisome position: 59.2

GC content: 42.61

Gene sequence:

>798_bases
GTGATTAAAGTTGTAGTAGCAGGTGCTCTAGGTAAAATGGGCCAGGAGTCCTGCAAGGCAGTATTAAATGCAGAAGGAAT
GGAATTAGTGGGAGCTATGGATTGCAAGGAATTTCATGGATCCATTGGATCATTCCTGGGTAAGCCAGAGGTAAATATTC
AAATATCTAATAATATCGAGCAAGTCCTACTAGAGCTAAAGCCGGATGTTTTAATTGATTTTACACGTCCTGGTGTTGTT
CAGGAAAATATAGAATTGGCATTGAAGCATGGTGTAAGACCGGTTATTGGAACCACTGGAATGGCTGCATCGGAAATAGA
AGGGTTCATAAAATCAGCTTCAGAAAAGAAAATAGGAGGCCTCATTGTACCAAACTTTGCCATTGGGGCGCTCCTAATGA
TAAAATTTGCAACCGAAGCAGCGAAATACTTTCCCAATGTGGAAATTATTGAGCTTCATCATGACCAGAAAATGGATGCT
CCTTCAGGGACTGCCCTTAAGACAGCAGAATCCATTGCCTCAGTAAGGGGGAACATGTCCCAGGGTATGCCCAGTGAGTT
CGAAAAGATTGATGGTGCCCGGGGTGGGGACTTTGAGGGAATGAAAATTCACAGTATTCGATTACCTGGTTTTGTGGCTC
ACCAGGAGGTAATTTTTGGTGGTACTGGGCAAACCCTCTCCATTCGCCATGATTCCATTGCTAGAGAATCCTTTATGCCG
GGACTCATATTGGCAGTAAGAAAGGTTATGAGTTTGGACCATATGGTCTATGGATTAGAAAACATATTGTTTGAATAA

Upstream 100 bases:

>100_bases
AATACACTGGATGTATCTAACTTGACAATCCTAAATGTGGTAATGGATAATTAAATTCAAAACAGTCTTTGACCTGCATA
AATATAAAGGTGGTGGTTTT

Downstream 100 bases:

>100_bases
CTAAATATGGCATTTTCCGCACTGACTGTAGGCCTTACGTACAAGCACCACCCCTTCCGATCTTTCATATCATGTAGTGT
GTCACAGATGGCAGAGAGGA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MIKVVVAGALGKMGQESCKAVLNAEGMELVGAMDCKEFHGSIGSFLGKPEVNIQISNNIEQVLLELKPDVLIDFTRPGVV
QENIELALKHGVRPVIGTTGMAASEIEGFIKSASEKKIGGLIVPNFAIGALLMIKFATEAAKYFPNVEIIELHHDQKMDA
PSGTALKTAESIASVRGNMSQGMPSEFEKIDGARGGDFEGMKIHSIRLPGFVAHQEVIFGGTGQTLSIRHDSIARESFMP
GLILAVRKVMSLDHMVYGLENILFE

Sequences:

>Translated_265_residues
MIKVVVAGALGKMGQESCKAVLNAEGMELVGAMDCKEFHGSIGSFLGKPEVNIQISNNIEQVLLELKPDVLIDFTRPGVV
QENIELALKHGVRPVIGTTGMAASEIEGFIKSASEKKIGGLIVPNFAIGALLMIKFATEAAKYFPNVEIIELHHDQKMDA
PSGTALKTAESIASVRGNMSQGMPSEFEKIDGARGGDFEGMKIHSIRLPGFVAHQEVIFGGTGQTLSIRHDSIARESFMP
GLILAVRKVMSLDHMVYGLENILFE
>Mature_265_residues
MIKVVVAGALGKMGQESCKAVLNAEGMELVGAMDCKEFHGSIGSFLGKPEVNIQISNNIEQVLLELKPDVLIDFTRPGVV
QENIELALKHGVRPVIGTTGMAASEIEGFIKSASEKKIGGLIVPNFAIGALLMIKFATEAAKYFPNVEIIELHHDQKMDA
PSGTALKTAESIASVRGNMSQGMPSEFEKIDGARGGDFEGMKIHSIRLPGFVAHQEVIFGGTGQTLSIRHDSIARESFMP
GLILAVRKVMSLDHMVYGLENILFE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=272, Percent_Identity=31.25, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28533; Mature: 28533

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVVVAGALGKMGQESCKAVLNAEGMELVGAMDCKEFHGSIGSFLGKPEVNIQISNNIE
CEEEEEECHHHHCCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCHH
QVLLELKPDVLIDFTRPGVVQENIELALKHGVRPVIGTTGMAASEIEGFIKSASEKKIGG
HHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCCCC
LIVPNFAIGALLMIKFATEAAKYFPNVEIIELHHDQKMDAPSGTALKTAESIASVRGNMS
EECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCC
QGMPSEFEKIDGARGGDFEGMKIHSIRLPGFVAHQEVIFGGTGQTLSIRHDSIARESFMP
CCCCHHHHHHCCCCCCCCCCEEEEEEECCCEEECCEEEECCCCCEEEECCHHHHHHHCCC
GLILAVRKVMSLDHMVYGLENILFE
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKVVVAGALGKMGQESCKAVLNAEGMELVGAMDCKEFHGSIGSFLGKPEVNIQISNNIE
CEEEEEECHHHHCCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCHH
QVLLELKPDVLIDFTRPGVVQENIELALKHGVRPVIGTTGMAASEIEGFIKSASEKKIGG
HHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCCCC
LIVPNFAIGALLMIKFATEAAKYFPNVEIIELHHDQKMDAPSGTALKTAESIASVRGNMS
EECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCC
QGMPSEFEKIDGARGGDFEGMKIHSIRLPGFVAHQEVIFGGTGQTLSIRHDSIARESFMP
CCCCHHHHHHCCCCCCCCCCEEEEEEECCCEEECCEEEECCCCCEEEECCHHHHHHHCCC
GLILAVRKVMSLDHMVYGLENILFE
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]