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The map label for this gene is resD [H]

Identifier: 134299753

GI number: 134299753

Start: 2091809

End: 2092501

Strand: Reverse

Name: resD [H]

Synonym: Dred_1903

Alternate gene names: 134299753

Gene position: 2092501-2091809 (Counterclockwise)

Preceding gene: 134299755

Following gene: 134299752

Centisome position: 57.99

GC content: 39.68

Gene sequence:

>693_bases
TTGCCCAAGCTGTTAATTGTTGATGATGAGGAGAAAATCAGAAATCTAATAAAGGTTTATTTGGTCAAGGAAGGCTTTGA
AGTAGACGAGTTGGACAACGGCAATCGGGTAGTAGATAGTATTAAAAGTTCTCACTTTGATATGGTCGTTCTGGATATAA
TGTTACCTGGTCCAGATGGTTTGTCCCTATGTAAGGAAATTAGAAAAATTTCCAACATCCCAATTATTATGTTAACTGCC
AAGGGAGATGAAATCGATCGGATTATTGGATTGGAGGTTGGGGCAGATGATTATATTGTTAAGCCCTTTAGCCCTAGAGA
ACTGGTAGCTAGGATCAATGCTATTTTAAGACGAGTAGCTGCACAGCCAATCATCCAAGAAGATCGTACAGCGATACTGA
GTTTCTCAGAATTGACCATTAATCCTGATAATCGAACCGTGGAGGTACGGGGAAGTGAAATTGCCTTAACCCCCAAGGAA
TTTGACTTACTTTATTTTATGGCCAAAACTCCGGGTCGTGCTTTTAGCCGTGAGAATTTATTAGAAAACGTTTGGGGTTA
TGACTTTTATGGCGATTTACGTACTGTTGATACTCATATAAATCGCCTGAGGGATAAACTCAATATGGAAGGGACAAAGC
AAGCCATTACAACGGTCTGGGGTGTGGGTTATAAATTTGAGGTAACTAAATGA

Upstream 100 bases:

>100_bases
AACGCAGTATACAGTGGAACCTTTTATACTCTGATTTTTTGTAGGGTTCATGGCGTGGTATAATAAAAGCGTATTCAAGT
TATAGAAAAAGGTGATTAGT

Downstream 100 bases:

>100_bases
TTGGTGGCAGTATAGTAAAAAAACTCTGGTTAGCAACATCTCTATTGGTTTTATTAGCAATGGGCGCCTCTACATTGACA
CAAATGTGGTTGCTAAAGAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPKLLIVDDEEKIRNLIKVYLVKEGFEVDELDNGNRVVDSIKSSHFDMVVLDIMLPGPDGLSLCKEIRKISNIPIIMLTA
KGDEIDRIIGLEVGADDYIVKPFSPRELVARINAILRRVAAQPIIQEDRTAILSFSELTINPDNRTVEVRGSEIALTPKE
FDLLYFMAKTPGRAFSRENLLENVWGYDFYGDLRTVDTHINRLRDKLNMEGTKQAITTVWGVGYKFEVTK

Sequences:

>Translated_230_residues
MPKLLIVDDEEKIRNLIKVYLVKEGFEVDELDNGNRVVDSIKSSHFDMVVLDIMLPGPDGLSLCKEIRKISNIPIIMLTA
KGDEIDRIIGLEVGADDYIVKPFSPRELVARINAILRRVAAQPIIQEDRTAILSFSELTINPDNRTVEVRGSEIALTPKE
FDLLYFMAKTPGRAFSRENLLENVWGYDFYGDLRTVDTHINRLRDKLNMEGTKQAITTVWGVGYKFEVTK
>Mature_229_residues
PKLLIVDDEEKIRNLIKVYLVKEGFEVDELDNGNRVVDSIKSSHFDMVVLDIMLPGPDGLSLCKEIRKISNIPIIMLTAK
GDEIDRIIGLEVGADDYIVKPFSPRELVARINAILRRVAAQPIIQEDRTAILSFSELTINPDNRTVEVRGSEIALTPKEF
DLLYFMAKTPGRAFSRENLLENVWGYDFYGDLRTVDTHINRLRDKLNMEGTKQAITTVWGVGYKFEVTK

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=44.1048034934498, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=40.9691629955947, Blast_Score=182, Evalue=1e-47,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=41.4096916299559, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=37.0044052863436, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=38.7665198237885, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=35.6521739130435, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=39.647577092511, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=33.7719298245614, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=36.5217391304348, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=37.6681614349776, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=32.15859030837, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=33.7777777777778, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=33.0543933054393, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=28.9473684210526, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=33.8983050847458, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788191, Length=122, Percent_Identity=31.1475409836066, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790299, Length=106, Percent_Identity=34.9056603773585, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26156; Mature: 26024

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLLIVDDEEKIRNLIKVYLVKEGFEVDELDNGNRVVDSIKSSHFDMVVLDIMLPGPDG
CCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCH
LSLCKEIRKISNIPIIMLTAKGDEIDRIIGLEVGADDYIVKPFSPRELVARINAILRRVA
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHH
AQPIIQEDRTAILSFSELTINPDNRTVEVRGSEIALTPKEFDLLYFMAKTPGRAFSRENL
HCCCHHCCCCEEEEEEEEEECCCCCEEEEECCEEEECCCCCEEEEEEECCCCCCHHHHHH
LENVWGYDFYGDLRTVDTHINRLRDKLNMEGTKQAITTVWGVGYKFEVTK
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure 
PKLLIVDDEEKIRNLIKVYLVKEGFEVDELDNGNRVVDSIKSSHFDMVVLDIMLPGPDG
CCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCH
LSLCKEIRKISNIPIIMLTAKGDEIDRIIGLEVGADDYIVKPFSPRELVARINAILRRVA
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHH
AQPIIQEDRTAILSFSELTINPDNRTVEVRGSEIALTPKEFDLLYFMAKTPGRAFSRENL
HCCCHHCCCCEEEEEEEEEECCCCCEEEEECCEEEECCCCCEEEEEEECCCCCCHHHHHH
LENVWGYDFYGDLRTVDTHINRLRDKLNMEGTKQAITTVWGVGYKFEVTK
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]