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The map label for this gene is ttdA [C]

Identifier: 134299725

GI number: 134299725

Start: 2057857

End: 2058708

Strand: Reverse

Name: ttdA [C]

Synonym: Dred_1872

Alternate gene names: 134299725

Gene position: 2058708-2057857 (Counterclockwise)

Preceding gene: 134299727

Following gene: 134299724

Centisome position: 57.06

GC content: 43.43

Gene sequence:

>852_bases
TTGCTTATCATTAGGACAATAGACTGTGAAGTAATTATATCTGAAGTAGCCCGCTTATGCCAGGAAGCTAACTTCAAGTT
GGAGGACGATGTTGTTCAATCCTTTAAATGTTCCTATGAAACTGAAGTTTCACAAAGTGGTAAAGAAATCCTGAATCTAC
TTATTGAAAATGCTGCCATAGCAGCTAACGAATCCATCCCTATGTGTCAGGATACAGGGGTTGCGGTGGTGTTTCTAGAA
TTAGGACAGGATACGCATATTATCAACGGCAATTTATATAAAGCTATTAATGAAGGTGTACGTAAGGGTTACCAAGAGGG
TTATCTAAGAAAATCAATGGTTGCGCACCCGCTGGAAAGGGTTAATACCGGGGATAATACCCCTGCTGTTATACATACCA
GGATTGTACCAGGGGACCAAGTTAAGATAACCGTTGCACCCAAGGGTGGGGGCAGTGAAAATATGAGTGCCTTAAAAATG
CTAAAACCAGCCGAAGGGGTAGAAGGAGTAAAGAATTTTATCCTTGAAACAGTCGAAAATGCAGGTCCCAACCCCTGTCC
GCCACTGATTGTGGGAGTTGGGATCGGCGGGACAATGGAAAAATGCGCACTGCTGGCAAAGGAGGCTTTATTGCGATCCG
TTGGGGAACCTCATCCTATGCCGGATATAGCAGAGTTGGAGCAAGAATTACTGGGTAAAATAAACAACTTGGGAATAGGG
CCTTCTGGCCTAGGTGGGAGAACCACCGCTTTGGCCGTCCATATTGAAATATTTGGTTCTCACATTGCTAGTTTACCTGT
AGCAGTTAACCTTAATTGCCATGCTGCAAGACATAAATCTGTTGTTATTTAG

Upstream 100 bases:

>100_bases
TTAAAAATTAGAAGGCTTTTTTAGATAAAAAATTGAAGTTGCATTTGGCATATACATTGCTATATGTGTTATAAAAATAT
TAAGAATCTTAACAGGGAGG

Downstream 100 bases:

>100_bases
GAGGATATGATGACAAAAGTTCATATATCAACACCCCTTGTGGAGGATGTTGTGAAAAGCCTTTGTATCGGTCAACAAGT
CTTAATCAGTGGGGTGATTT

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLIIRTIDCEVIISEVARLCQEANFKLEDDVVQSFKCSYETEVSQSGKEILNLLIENAAIAANESIPMCQDTGVAVVFLE
LGQDTHIINGNLYKAINEGVRKGYQEGYLRKSMVAHPLERVNTGDNTPAVIHTRIVPGDQVKITVAPKGGGSENMSALKM
LKPAEGVEGVKNFILETVENAGPNPCPPLIVGVGIGGTMEKCALLAKEALLRSVGEPHPMPDIAELEQELLGKINNLGIG
PSGLGGRTTALAVHIEIFGSHIASLPVAVNLNCHAARHKSVVI

Sequences:

>Translated_283_residues
MLIIRTIDCEVIISEVARLCQEANFKLEDDVVQSFKCSYETEVSQSGKEILNLLIENAAIAANESIPMCQDTGVAVVFLE
LGQDTHIINGNLYKAINEGVRKGYQEGYLRKSMVAHPLERVNTGDNTPAVIHTRIVPGDQVKITVAPKGGGSENMSALKM
LKPAEGVEGVKNFILETVENAGPNPCPPLIVGVGIGGTMEKCALLAKEALLRSVGEPHPMPDIAELEQELLGKINNLGIG
PSGLGGRTTALAVHIEIFGSHIASLPVAVNLNCHAARHKSVVI
>Mature_283_residues
MLIIRTIDCEVIISEVARLCQEANFKLEDDVVQSFKCSYETEVSQSGKEILNLLIENAAIAANESIPMCQDTGVAVVFLE
LGQDTHIINGNLYKAINEGVRKGYQEGYLRKSMVAHPLERVNTGDNTPAVIHTRIVPGDQVKITVAPKGGGSENMSALKM
LKPAEGVEGVKNFILETVENAGPNPCPPLIVGVGIGGTMEKCALLAKEALLRSVGEPHPMPDIAELEQELLGKINNLGIG
PSGLGGRTTALAVHIEIFGSHIASLPVAVNLNCHAARHKSVVI

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=272, Percent_Identity=35.6617647058824, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1790564, Length=254, Percent_Identity=33.0708661417323, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787897, Length=254, Percent_Identity=34.251968503937, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30183; Mature: 30183

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIRTIDCEVIISEVARLCQEANFKLEDDVVQSFKCSYETEVSQSGKEILNLLIENAAI
CEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AANESIPMCQDTGVAVVFLELGQDTHIINGNLYKAINEGVRKGYQEGYLRKSMVAHPLER
CCCCCCCCCCCCCEEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTGDNTPAVIHTRIVPGDQVKITVAPKGGGSENMSALKMLKPAEGVEGVKNFILETVEN
CCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
AGPNPCPPLIVGVGIGGTMEKCALLAKEALLRSVGEPHPMPDIAELEQELLGKINNLGIG
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
PSGLGGRTTALAVHIEIFGSHIASLPVAVNLNCHAARHKSVVI
CCCCCCCEEEEEEEHHHHHHHHHHCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLIIRTIDCEVIISEVARLCQEANFKLEDDVVQSFKCSYETEVSQSGKEILNLLIENAAI
CEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AANESIPMCQDTGVAVVFLELGQDTHIINGNLYKAINEGVRKGYQEGYLRKSMVAHPLER
CCCCCCCCCCCCCEEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTGDNTPAVIHTRIVPGDQVKITVAPKGGGSENMSALKMLKPAEGVEGVKNFILETVEN
CCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
AGPNPCPPLIVGVGIGGTMEKCALLAKEALLRSVGEPHPMPDIAELEQELLGKINNLGIG
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
PSGLGGRTTALAVHIEIFGSHIASLPVAVNLNCHAARHKSVVI
CCCCCCCEEEEEEEHHHHHHHHHHCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]