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The map label for this gene is fdhA [H]

Identifier: 134299708

GI number: 134299708

Start: 2037430

End: 2039013

Strand: Reverse

Name: fdhA [H]

Synonym: Dred_1855

Alternate gene names: 134299708

Gene position: 2039013-2037430 (Counterclockwise)

Preceding gene: 134299709

Following gene: 134299706

Centisome position: 56.51

GC content: 46.84

Gene sequence:

>1584_bases
ATGACTAACAGCATTAATGAAGTGGCGGGGGCAGATTTTATTTTAGCCATTGGGACAAACACCAGCGAGACCCACCCCAT
AATCGCATTACAAGTGAAAAAGGCACTGCGTCAGGGGGCTACCCTGGCAGTGGTAGACCCGCGCAGAACGGAAGTGGCTC
AATTAGCTCAGTATCACCTTCGGGTGAAGTCGGGTACAGATGTGGCATTATTGAACGGATTGGCCCATGTAATTATCGAT
GAAGGCCTTTGGAACAAAGAATTTGTTGATAAGCGTACCGAAGGGTTTGTGGCATTGAAGGAATTAGCAGAAAGATATAC
GCCCGACTATGTGGAAGAGATTACAGGGGTGCCGGCTGAAACTTTGCGTGAGGTGGCCCGGGGCTATGCAAGGGCGCAGA
ATGCCACGATTTTGTATACAATGGGCTTAACTCAGCATGTTAATGGCACCCATAATGTTTTTGCGGTGGCCAATTTAGCT
ATGCTTTGCGGACAAATTGGCAAGAAACATAGTGGAGTGAATCCTCTGCGTGGTCAAAATAATGTGCAGGGCTCCTGTGA
TATGGGTGCCCTGCCCGATGTGTTGACAGGTTATCAAAAAATAACCGATAACTTAGTTAGGGCAAAGTTTGCCCAGGTCT
GGAATGTTCCTGAGCTACCCCCTCAACCTGGACTAACCATAGGTGAAATGATGAAAGCCGCCGCTGAGGGGAAAGTAAAA
GGAATGTACATTATGGGGGAAAATCCCGTACTCTCCGATGCAGATGCCAATCATATCAAGGAAGCTTTGAGCAAGCTAGA
CTTTCTAGTGGTACAGGATATCTTCTTAACAGAAACTGCCCAAATGGCAGATGTGGTATTGCCGGCAGCCAGTTTTGCAG
AAAAGGACGGAACTTTTACCAATACCGAAAGGCGTGTCCAGCGGGTGCGCAAAGCCATTGAACCAGTGGGAGAGGCTAAG
GCCGATTGGGAAATACTTTGCAAAGTTGCCAATGCCATGGGATTTTCCATGAGTTACGAATCGCCGGCAGAAATCATGAA
GGAAATTGCCAGTCTTACACCTTCCTACGGGGGTATTTCCTATACTCGGCTGGAACAGGAAAGCCTGCAGTGGCCTTGTC
CAACTTCCGATCATCCTGGTACCCCCCTGCTGCATAGGGGTGTTTTTCTGCGTGGGCTTGGAAAATTTCATCCAATAGAA
TATTTGCCTTCATCAGAAACGCCAGATCATGAATACCCACTGATATTAAGTACTGGTAGGAGATTGTATCATTACCATAC
GGGGACCATGACCTTACGATCTGCTGCCCTAGAGCAACACTACCCTAACGAATATTTAGAAATGAATGCGATGGATGCAG
AAAAATATGGTTTAGAAGATGGAGACAGGGTTAAAGTTTCCTCCCGTCGAGGCTCAGTAGAAGTGGTAGTTCGAGTTATG
GATGTAACCCCTGTTGGATTTGTCTTTACTTCTTTCCACTATCCTCTGGTTCCGGTGAATCAGTTAACCAATGCAGCCTG
TGATCCTATTTCTAGGGTTCCTGAATTAAAAGCATGTGCGGTAAAGGTGGAGAAGGTAACATAG

Upstream 100 bases:

>100_bases
TACTCGTACGGTTTTCGGCACCAATAATATCGATCATTGTGCACGTCTTTGACATGCTCCCACTGTCGCCGGTCTGGCGG
CATCCTTTGGCAGCGGTGCA

Downstream 100 bases:

>100_bases
ATTGTCGACACAGCAAATAACCAACCTGTTTGGTTGGTTATTTGCTATCGTTTTGCTCAGGACCAGTTATACGGGTGCTG
GGAGTTAGGTATTCTATTAT

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MTNSINEVAGADFILAIGTNTSETHPIIALQVKKALRQGATLAVVDPRRTEVAQLAQYHLRVKSGTDVALLNGLAHVIID
EGLWNKEFVDKRTEGFVALKELAERYTPDYVEEITGVPAETLREVARGYARAQNATILYTMGLTQHVNGTHNVFAVANLA
MLCGQIGKKHSGVNPLRGQNNVQGSCDMGALPDVLTGYQKITDNLVRAKFAQVWNVPELPPQPGLTIGEMMKAAAEGKVK
GMYIMGENPVLSDADANHIKEALSKLDFLVVQDIFLTETAQMADVVLPAASFAEKDGTFTNTERRVQRVRKAIEPVGEAK
ADWEILCKVANAMGFSMSYESPAEIMKEIASLTPSYGGISYTRLEQESLQWPCPTSDHPGTPLLHRGVFLRGLGKFHPIE
YLPSSETPDHEYPLILSTGRRLYHYHTGTMTLRSAALEQHYPNEYLEMNAMDAEKYGLEDGDRVKVSSRRGSVEVVVRVM
DVTPVGFVFTSFHYPLVPVNQLTNAACDPISRVPELKACAVKVEKVT

Sequences:

>Translated_527_residues
MTNSINEVAGADFILAIGTNTSETHPIIALQVKKALRQGATLAVVDPRRTEVAQLAQYHLRVKSGTDVALLNGLAHVIID
EGLWNKEFVDKRTEGFVALKELAERYTPDYVEEITGVPAETLREVARGYARAQNATILYTMGLTQHVNGTHNVFAVANLA
MLCGQIGKKHSGVNPLRGQNNVQGSCDMGALPDVLTGYQKITDNLVRAKFAQVWNVPELPPQPGLTIGEMMKAAAEGKVK
GMYIMGENPVLSDADANHIKEALSKLDFLVVQDIFLTETAQMADVVLPAASFAEKDGTFTNTERRVQRVRKAIEPVGEAK
ADWEILCKVANAMGFSMSYESPAEIMKEIASLTPSYGGISYTRLEQESLQWPCPTSDHPGTPLLHRGVFLRGLGKFHPIE
YLPSSETPDHEYPLILSTGRRLYHYHTGTMTLRSAALEQHYPNEYLEMNAMDAEKYGLEDGDRVKVSSRRGSVEVVVRVM
DVTPVGFVFTSFHYPLVPVNQLTNAACDPISRVPELKACAVKVEKVT
>Mature_526_residues
TNSINEVAGADFILAIGTNTSETHPIIALQVKKALRQGATLAVVDPRRTEVAQLAQYHLRVKSGTDVALLNGLAHVIIDE
GLWNKEFVDKRTEGFVALKELAERYTPDYVEEITGVPAETLREVARGYARAQNATILYTMGLTQHVNGTHNVFAVANLAM
LCGQIGKKHSGVNPLRGQNNVQGSCDMGALPDVLTGYQKITDNLVRAKFAQVWNVPELPPQPGLTIGEMMKAAAEGKVKG
MYIMGENPVLSDADANHIKEALSKLDFLVVQDIFLTETAQMADVVLPAASFAEKDGTFTNTERRVQRVRKAIEPVGEAKA
DWEILCKVANAMGFSMSYESPAEIMKEIASLTPSYGGISYTRLEQESLQWPCPTSDHPGTPLLHRGVFLRGLGKFHPIEY
LPSSETPDHEYPLILSTGRRLYHYHTGTMTLRSAALEQHYPNEYLEMNAMDAEKYGLEDGDRVKVSSRRGSVEVVVRVMD
VTPVGFVFTSFHYPLVPVNQLTNAACDPISRVPELKACAVKVEKVT

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=533, Percent_Identity=42.4015009380863, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI3868720, Length=444, Percent_Identity=27.7027027027027, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI3868719, Length=446, Percent_Identity=29.1479820627803, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788534, Length=363, Percent_Identity=26.4462809917355, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787778, Length=578, Percent_Identity=23.8754325259516, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081797, Length=564, Percent_Identity=22.3404255319149, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI145693196, Length=334, Percent_Identity=25.4491017964072, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081994, Length=515, Percent_Identity=22.9126213592233, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787870, Length=367, Percent_Identity=25.8855585831063, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI171474008, Length=566, Percent_Identity=23.4982332155477, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787231, Length=489, Percent_Identity=23.3128834355828, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565758, Length=190, Percent_Identity=32.6315789473684, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 57951; Mature: 57820

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSINEVAGADFILAIGTNTSETHPIIALQVKKALRQGATLAVVDPRRTEVAQLAQYHL
CCCCCCHHCCCCEEEEECCCCCCCCCEEHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
RVKSGTDVALLNGLAHVIIDEGLWNKEFVDKRTEGFVALKELAERYTPDYVEEITGVPAE
EECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHH
TLREVARGYARAQNATILYTMGLTQHVNGTHNVFAVANLAMLCGQIGKKHSGVNPLRGQN
HHHHHHHHHHHHCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NVQGSCDMGALPDVLTGYQKITDNLVRAKFAQVWNVPELPPQPGLTIGEMMKAAAEGKVK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEE
GMYIMGENPVLSDADANHIKEALSKLDFLVVQDIFLTETAQMADVVLPAASFAEKDGTFT
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NTERRVQRVRKAIEPVGEAKADWEILCKVANAMGFSMSYESPAEIMKEIASLTPSYGGIS
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCE
YTRLEQESLQWPCPTSDHPGTPLLHRGVFLRGLGKFHPIEYLPSSETPDHEYPLILSTGR
EEEECHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCC
RLYHYHTGTMTLRSAALEQHYPNEYLEMNAMDAEKYGLEDGDRVKVSSRRGSVEVVVRVM
EEEEEECCCHHHHHHHHHHHCCHHHHEECCCCHHHCCCCCCCEEEEECCCCCEEEEEEEE
DVTPVGFVFTSFHYPLVPVNQLTNAACDPISRVPELKACAVKVEKVT
CCCCHHHHHHCCCCCCCCHHHHHHHHCCHHHHCCCHHHHHEEEECCC
>Mature Secondary Structure 
TNSINEVAGADFILAIGTNTSETHPIIALQVKKALRQGATLAVVDPRRTEVAQLAQYHL
CCCCCHHCCCCEEEEECCCCCCCCCEEHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
RVKSGTDVALLNGLAHVIIDEGLWNKEFVDKRTEGFVALKELAERYTPDYVEEITGVPAE
EECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHH
TLREVARGYARAQNATILYTMGLTQHVNGTHNVFAVANLAMLCGQIGKKHSGVNPLRGQN
HHHHHHHHHHHHCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NVQGSCDMGALPDVLTGYQKITDNLVRAKFAQVWNVPELPPQPGLTIGEMMKAAAEGKVK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEE
GMYIMGENPVLSDADANHIKEALSKLDFLVVQDIFLTETAQMADVVLPAASFAEKDGTFT
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NTERRVQRVRKAIEPVGEAKADWEILCKVANAMGFSMSYESPAEIMKEIASLTPSYGGIS
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCE
YTRLEQESLQWPCPTSDHPGTPLLHRGVFLRGLGKFHPIEYLPSSETPDHEYPLILSTGR
EEEECHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCC
RLYHYHTGTMTLRSAALEQHYPNEYLEMNAMDAEKYGLEDGDRVKVSSRRGSVEVVVRVM
EEEEEECCCHHHHHHHHHHHCCHHHHEECCCCHHHCCCCCCCEEEEECCCCCEEEEEEEE
DVTPVGFVFTSFHYPLVPVNQLTNAACDPISRVPELKACAVKVEKVT
CCCCHHHHHHCCCCCCCCHHHHHHHHCCHHHHCCCHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]