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The map label for this gene is nuoG2 [H]

Identifier: 134299709

GI number: 134299709

Start: 2039062

End: 2040117

Strand: Reverse

Name: nuoG2 [H]

Synonym: Dred_1856

Alternate gene names: 134299709

Gene position: 2040117-2039062 (Counterclockwise)

Preceding gene: 134299710

Following gene: 134299708

Centisome position: 56.54

GC content: 45.55

Gene sequence:

>1056_bases
TTGTCAAATGTTAACATAAATATAAATGGGCAGCAAATATTAGTTCCCGCTGGCAGCACTATACTAGAGGCGGCTACGCA
AGTGGGTATTTTCATTCCTACCCTTTGCCATGACCCAGAATTGACTTCCCAGGGATCCTGTCGAATCTGTGTTGTGGAGC
TCAAAGATTCCGGAAAACTGATAATATCTTGTGCCACCTCTGTTAGAGAAGGCATGGTGGTAGATACAGAATCTCCAAGC
GTTCTAGAGGCCCGCAGGACCATCTTGGAATTGCTATTGGCCAATCACCCCCAGGATTGTCTTACCTGTGGGAAAAACGG
GGACTGCAGGTTGCAAGATTATGCTTATCGTTACGGCGTAACTGGACCAGGCTTTTCTGGCCAGCGCCACAATTATGAAA
TTGAAAAAGATAACCCTTTTATCTTGAGGGATATGAACAAGTGCATCTTATGTGGCAAATGTATAAGGGCATGCGATGAA
ATACAAGGTAACCATGTATTGGACTTTGCCTACCGGGGCTTCCACACCAAGATCACCACAGCTATGGATCTGCCCCTATC
TAAATCGGAATGTGTCTATTGCGGAAACTGTGTAGCGGTTTGCCCGGTGGGCGCCCTACAAGAAAAGGGTTTACGCAGCC
GGGCACGGACCTGGGAAGTGAAAAAAGTAAAGACCACTTGTCCCTATTGTGGAACAGGTTGCAGTTTGGAACTCAATGTG
AAGGGTGGTCAGGTTGTTGGTGTTACCTCCTGTCAGGGAGAGGTTAATGGCAGGGCGCTCTGTATTAAGGGACGATTTGG
TTATGGTTTTATTCATCACCCTGATCGATTAAAAAAACCATTAATTAAACACAAGGGAAAATTTGTTGAAGCCACCTGGG
AAGAGGCCATCGCCCTGGTAGCCAAGAAAATGAGTGCAATAAAAAATGACCATGGTAATGATGCTTTGGCGGTGTTGAGT
TCGGCCCGCTGTACCAATGAAGAGAATTACTTATTGCAAAAACTTACTCGTACGGTTTTCGGCACCAATAATATCGATCA
TTGTGCACGTCTTTGA

Upstream 100 bases:

>100_bases
CATAGATATCAAAGCTTGCATAAAATGTGGCAATTGCCTGCAAAAATGTAAATTTGGTGCAGTTCAAAAGAGGTAGATGG
CTTTTGGGAGAGTGAAGAGT

Downstream 100 bases:

>100_bases
CATGCTCCCACTGTCGCCGGTCTGGCGGCATCCTTTGGCAGCGGTGCAATGACTAACAGCATTAATGAAGTGGCGGGGGC
AGATTTTATTTTAGCCATTG

Product: molybdopterin oxidoreductase Fe4S4 region

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSNVNININGQQILVPAGSTILEAATQVGIFIPTLCHDPELTSQGSCRICVVELKDSGKLIISCATSVREGMVVDTESPS
VLEARRTILELLLANHPQDCLTCGKNGDCRLQDYAYRYGVTGPGFSGQRHNYEIEKDNPFILRDMNKCILCGKCIRACDE
IQGNHVLDFAYRGFHTKITTAMDLPLSKSECVYCGNCVAVCPVGALQEKGLRSRARTWEVKKVKTTCPYCGTGCSLELNV
KGGQVVGVTSCQGEVNGRALCIKGRFGYGFIHHPDRLKKPLIKHKGKFVEATWEEAIALVAKKMSAIKNDHGNDALAVLS
SARCTNEENYLLQKLTRTVFGTNNIDHCARL

Sequences:

>Translated_351_residues
MSNVNININGQQILVPAGSTILEAATQVGIFIPTLCHDPELTSQGSCRICVVELKDSGKLIISCATSVREGMVVDTESPS
VLEARRTILELLLANHPQDCLTCGKNGDCRLQDYAYRYGVTGPGFSGQRHNYEIEKDNPFILRDMNKCILCGKCIRACDE
IQGNHVLDFAYRGFHTKITTAMDLPLSKSECVYCGNCVAVCPVGALQEKGLRSRARTWEVKKVKTTCPYCGTGCSLELNV
KGGQVVGVTSCQGEVNGRALCIKGRFGYGFIHHPDRLKKPLIKHKGKFVEATWEEAIALVAKKMSAIKNDHGNDALAVLS
SARCTNEENYLLQKLTRTVFGTNNIDHCARL
>Mature_350_residues
SNVNININGQQILVPAGSTILEAATQVGIFIPTLCHDPELTSQGSCRICVVELKDSGKLIISCATSVREGMVVDTESPSV
LEARRTILELLLANHPQDCLTCGKNGDCRLQDYAYRYGVTGPGFSGQRHNYEIEKDNPFILRDMNKCILCGKCIRACDEI
QGNHVLDFAYRGFHTKITTAMDLPLSKSECVYCGNCVAVCPVGALQEKGLRSRARTWEVKKVKTTCPYCGTGCSLELNVK
GGQVVGVTSCQGEVNGRALCIKGRFGYGFIHHPDRLKKPLIKHKGKFVEATWEEAIALVAKKMSAIKNDHGNDALAVLSS
ARCTNEENYLLQKLTRTVFGTNNIDHCARL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=317, Percent_Identity=31.2302839116719, Blast_Score=171, Evalue=7e-43,
Organism=Escherichia coli, GI145693161, Length=338, Percent_Identity=28.1065088757396, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI3868721, Length=139, Percent_Identity=44.6043165467626, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788534, Length=142, Percent_Identity=33.0985915492958, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17565758, Length=307, Percent_Identity=33.8762214983713, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI32566231, Length=307, Percent_Identity=33.2247557003257, Blast_Score=161, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI193209088, Length=249, Percent_Identity=34.136546184739, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24640559, Length=302, Percent_Identity=31.7880794701987, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24640557, Length=302, Percent_Identity=31.7880794701987, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38459; Mature: 38328

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
6.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVNININGQQILVPAGSTILEAATQVGIFIPTLCHDPELTSQGSCRICVVELKDSGKL
CCCEEEEECCCEEEEECCCHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCE
IISCATSVREGMVVDTESPSVLEARRTILELLLANHPQDCLTCGKNGDCRLQDYAYRYGV
EEEEECHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEEEEEECC
TGPGFSGQRHNYEIEKDNPFILRDMNKCILCGKCIRACDEIQGNHVLDFAYRGFHTKITT
CCCCCCCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEE
AMDLPLSKSECVYCGNCVAVCPVGALQEKGLRSRARTWEVKKVKTTCPYCGTGCSLELNV
EEECCCCCCCEEEECCCCEECCCCHHHHHHHHHHHHCEEEEEEEECCCCCCCCCEEEEEE
KGGQVVGVTSCQGEVNGRALCIKGRFGYGFIHHPDRLKKPLIKHKGKFVEATWEEAIALV
CCCEEEEEEECCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHHCCCEEEHHHHHHHHHH
AKKMSAIKNDHGNDALAVLSSARCTNEENYLLQKLTRTVFGTNNIDHCARL
HHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
SNVNININGQQILVPAGSTILEAATQVGIFIPTLCHDPELTSQGSCRICVVELKDSGKL
CCEEEEECCCEEEEECCCHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCE
IISCATSVREGMVVDTESPSVLEARRTILELLLANHPQDCLTCGKNGDCRLQDYAYRYGV
EEEEECHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEEEEEECC
TGPGFSGQRHNYEIEKDNPFILRDMNKCILCGKCIRACDEIQGNHVLDFAYRGFHTKITT
CCCCCCCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEE
AMDLPLSKSECVYCGNCVAVCPVGALQEKGLRSRARTWEVKKVKTTCPYCGTGCSLELNV
EEECCCCCCCEEEECCCCEECCCCHHHHHHHHHHHHCEEEEEEEECCCCCCCCCEEEEEE
KGGQVVGVTSCQGEVNGRALCIKGRFGYGFIHHPDRLKKPLIKHKGKFVEATWEEAIALV
CCCEEEEEEECCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHHCCCEEEHHHHHHHHHH
AKKMSAIKNDHGNDALAVLSSARCTNEENYLLQKLTRTVFGTNNIDHCARL
HHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]