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The map label for this gene is resE [H]

Identifier: 134299696

GI number: 134299696

Start: 2022574

End: 2023548

Strand: Reverse

Name: resE [H]

Synonym: Dred_1842

Alternate gene names: 134299696

Gene position: 2023548-2022574 (Counterclockwise)

Preceding gene: 134299697

Following gene: 134299695

Centisome position: 56.08

GC content: 36.21

Gene sequence:

>975_bases
ATGGCTAAAAAAATATTACAGGATAATACAAGAGTACTTTTTGACAAAGAGTTTGATGTGTTAAAGGTAGCCAAAGAGAA
ATTGAACCGCGAGCAGGTACAAAAGAGTGCTTTATACCCAGAATACAAAGAATTAGTAGAGAGTTATGAGAAACTGTTAA
AGGTTACCGCTAAAATATTTAAAATCAGTGATATTCAGGGTAGGGTTTTAAAAAATCATGAAAGCCATTTAAACAAAGTA
AATGAAAATCTACGTCAACTGGAAGAATCCCGGCGCCAACTGGTTTCTGATATTTCTCATGAATTAGGTACCCCTATGAC
CTCCATTCAGGGATATCTTAAGGCAATGCTTGATAACGTAATAGAACCCGATAGGCAATACTTAAATTTAATTTATGATA
AGACCTTGCTTGTTAACCAGTTGGTTGAAGATCTGTTTGAGTTATCGAAGCTGGAGGCTAACCAGGTAAGTTTTAATTTT
AAGGAAGTTACTATACAAGATTTAATGGCAAATATAACACGGAAATTTGCCTTAGACTTTAAAAATTCAGGTATAAACTT
TATGATTGACCCCATAGAAAACCTTACCCCAGACAATCACATTATAATGAATGTTGACCCTGCCCGCATTGATCAAGTGA
TGGTCAACTTAATAAATAATGCAGTTAAATACACTCCCACAGGCGGTACTATTCGCATTCAGTGTCAAATACAGAACGCT
GAAAAAGATGGAGAAGTCATCATAAAAGTAATAGATAGCGGGTCCGGAATTGATGAAAAGTCCCTCCCCTTTGTCTTTGA
TCGTTTCTTTAAAGGAACTCAGTCCCAAAAGGTTGGTGGTACTGGCTTAGGTTTAGCCATTGCCAAGCAAATAATCATTA
AACATGGTGGCTACATTGGAGTAGACAGCATGGTCAACAAAGGAAGTACCTTTTATTTTTCTCTTCCGATATCTGTGCAG
CATAAATCGTATTAA

Upstream 100 bases:

>100_bases
GAAAGTGAGCTTGAATGTGCGGAGGAATTTAAAGAGGACTTAAATTTACCCTTCTACATTATTCCTCGGGAGGATAATTA
GTTGTAGAGGGAGATTGTAA

Downstream 100 bases:

>100_bases
ACTATAATTTAAAATTTTGGGAGTAACCGTAATGAACAAAGGGCTTAATGAAAAGGACCAATTTGTCAGAATAAGTTCTA
TGCTGGATGCCAGTGTAATG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAKKILQDNTRVLFDKEFDVLKVAKEKLNREQVQKSALYPEYKELVESYEKLLKVTAKIFKISDIQGRVLKNHESHLNKV
NENLRQLEESRRQLVSDISHELGTPMTSIQGYLKAMLDNVIEPDRQYLNLIYDKTLLVNQLVEDLFELSKLEANQVSFNF
KEVTIQDLMANITRKFALDFKNSGINFMIDPIENLTPDNHIIMNVDPARIDQVMVNLINNAVKYTPTGGTIRIQCQIQNA
EKDGEVIIKVIDSGSGIDEKSLPFVFDRFFKGTQSQKVGGTGLGLAIAKQIIIKHGGYIGVDSMVNKGSTFYFSLPISVQ
HKSY

Sequences:

>Translated_324_residues
MAKKILQDNTRVLFDKEFDVLKVAKEKLNREQVQKSALYPEYKELVESYEKLLKVTAKIFKISDIQGRVLKNHESHLNKV
NENLRQLEESRRQLVSDISHELGTPMTSIQGYLKAMLDNVIEPDRQYLNLIYDKTLLVNQLVEDLFELSKLEANQVSFNF
KEVTIQDLMANITRKFALDFKNSGINFMIDPIENLTPDNHIIMNVDPARIDQVMVNLINNAVKYTPTGGTIRIQCQIQNA
EKDGEVIIKVIDSGSGIDEKSLPFVFDRFFKGTQSQKVGGTGLGLAIAKQIIIKHGGYIGVDSMVNKGSTFYFSLPISVQ
HKSY
>Mature_323_residues
AKKILQDNTRVLFDKEFDVLKVAKEKLNREQVQKSALYPEYKELVESYEKLLKVTAKIFKISDIQGRVLKNHESHLNKVN
ENLRQLEESRRQLVSDISHELGTPMTSIQGYLKAMLDNVIEPDRQYLNLIYDKTLLVNQLVEDLFELSKLEANQVSFNFK
EVTIQDLMANITRKFALDFKNSGINFMIDPIENLTPDNHIIMNVDPARIDQVMVNLINNAVKYTPTGGTIRIQCQIQNAE
KDGEVIIKVIDSGSGIDEKSLPFVFDRFFKGTQSQKVGGTGLGLAIAKQIIIKHGGYIGVDSMVNKGSTFYFSLPISVQH
KSY

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=31.5789473684211, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=31.25, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788393, Length=284, Percent_Identity=27.112676056338, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788549, Length=253, Percent_Identity=30.0395256916996, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=28.3950617283951, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=29.8701298701299, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=25, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=283, Percent_Identity=25.7950530035336, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786783, Length=253, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=28.8793103448276, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=28.936170212766, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=24.4897959183673, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787894, Length=302, Percent_Identity=23.5099337748344, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=204, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=25.5060728744939, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=265, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789403, Length=223, Percent_Identity=25.1121076233184, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789808, Length=253, Percent_Identity=22.9249011857708, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 36831; Mature: 36700

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKILQDNTRVLFDKEFDVLKVAKEKLNREQVQKSALYPEYKELVESYEKLLKVTAKIF
CCCCHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KISDIQGRVLKNHESHLNKVNENLRQLEESRRQLVSDISHELGTPMTSIQGYLKAMLDNV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IEPDRQYLNLIYDKTLLVNQLVEDLFELSKLEANQVSFNFKEVTIQDLMANITRKFALDF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHHHHHHHHHHHC
KNSGINFMIDPIENLTPDNHIIMNVDPARIDQVMVNLINNAVKYTPTGGTIRIQCQIQNA
CCCCCCEEECCHHCCCCCCEEEEECCHHHHHHHHHHHHHCCEEECCCCCEEEEEEEEECC
EKDGEVIIKVIDSGSGIDEKSLPFVFDRFFKGTQSQKVGGTGLGLAIAKQIIIKHGGYIG
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEC
VDSMVNKGSTFYFSLPISVQHKSY
HHHHHCCCCEEEEEEEEEECCCCC
>Mature Secondary Structure 
AKKILQDNTRVLFDKEFDVLKVAKEKLNREQVQKSALYPEYKELVESYEKLLKVTAKIF
CCCHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KISDIQGRVLKNHESHLNKVNENLRQLEESRRQLVSDISHELGTPMTSIQGYLKAMLDNV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IEPDRQYLNLIYDKTLLVNQLVEDLFELSKLEANQVSFNFKEVTIQDLMANITRKFALDF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHHHHHHHHHHHC
KNSGINFMIDPIENLTPDNHIIMNVDPARIDQVMVNLINNAVKYTPTGGTIRIQCQIQNA
CCCCCCEEECCHHCCCCCCEEEEECCHHHHHHHHHHHHHCCEEECCCCCEEEEEEEEECC
EKDGEVIIKVIDSGSGIDEKSLPFVFDRFFKGTQSQKVGGTGLGLAIAKQIIIKHGGYIG
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEC
VDSMVNKGSTFYFSLPISVQHKSY
HHHHHCCCCEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]