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The map label for this gene is aegA [C]

Identifier: 134299648

GI number: 134299648

Start: 1965581

End: 1966969

Strand: Reverse

Name: aegA [C]

Synonym: Dred_1794

Alternate gene names: 134299648

Gene position: 1966969-1965581 (Counterclockwise)

Preceding gene: 134299655

Following gene: 134299646

Centisome position: 54.52

GC content: 42.98

Gene sequence:

>1389_bases
ATGAATCCGGTATCGGAAGTGACTAGACTCCGTAGAGATATCTTTACCAGAGTAGCGCACTGGGCTTTAAACCACCCTCT
AGATGTACCTATGGAAATGGATATATCTCAAGTTGTAAAAGAAATCATACCGGACGGACCGGCTCGTTATCGTTGTTGCA
TCCATAAAGAAAGAGCAATTGTGGAAGAACGGATTAAGATTGCTGTGGGCTTGATTCAACCTGAACATCGAGTGACGGTT
ATATCAGAAGCCTGTAATGGATGTTCGCTAAATAAATATGTAGTAACAGATGCTTGTCAAAACTGTGTGGCACATCCATG
CAGAAACAGTTGCCCTAAGAAAGCCATATCAGTAATTCAAAATCGCGCCTTTATTGATCAAAATTCCTGTGTGGAATGTG
GGAAATGTGCTAATGCCTGTCCTTATAACGCTATCATTGAGGTTACCCGTCCCTGTGAAAGGGCCTGTGCCCTAAAGGCC
ATAAAAGTTGATGATTCCCGCAAGGCAGTGATTGACCACGAGTTGTGTGCATCCTGTGGTTTATGCGTCACCGTGTGCCC
CTTTGGTGCCATCACAGATCATTCCCAAATGATCGATGTTATATGTTCTCTTAGGGTAAGTGAGCAACCGCATGTGGCCG
TGATAGCGCCTGCCATAGCAGGTCAATTTGGTCTAAAGGTTAGTCCCGACCAAATCAAAGCTGCACTTTTGAAATTAGGT
TTTGATGAAGTCATTGAAGCTGCTTTAGGGGCAGATATGGTTGCCCAAGAAGAAGCTGGAGAGATTAAACTTCATGCAGA
AGATAAAAAAATTATGTTAAACTCATGCTGCCCGGCTGTTGTAAAGGCTGTGTCACTAAAATTACCAGAATTGAAGGATT
GTATCTCCACTACCCTATCTCCCATGCGTGTAACTGGCAAACTGATTAAAGAAAGATACGATAATAGAGTAATAACTGTC
TTTATAGGTCCTTGTATAGCAAAAAAAGAGGAAGCAACCCATGGTGATGAGATTGATATGGTGTTAACCTTTGAAGAATT
AGCGGCAATATTCTCGGCATCTGAATTAGAAATCTCTTCCCTCGAGCCTGTGGAATTAAAGGATGCGTCTCCTAATGGCA
GATTATTTGCCAGAGCCGGTGGTGTAAGTACGGCGGTTCGCAAGCATCTGGGAGAAATGGAACTGAATGTTCTGCGGGTG
CAAGGTTTAGGACAATGTCTAACAACATTAAAAACCTCTGCAAAAAAATCAGACTCTAATTTTACTTTTATTGAATGTAT
GGCCTGCGAAGGCGGTTGTGTGGGTGGACCGGGGACGATGGTTGCATCCACAGTGGGAACAAGGGCTGTTGAAAAACATG
CTGGAGAAAGTATCATATTACCCAAATAA

Upstream 100 bases:

>100_bases
CAGATAGTTTTTTAAATTAGAACATATATCGATAAAATTGACACCCAATTAATCCACATGAGATAATTTGCACAAGCAGA
ATCAAACAGGAGGAGATTAT

Downstream 100 bases:

>100_bases
AAAACCGGCGTTAGCCGGTTTTTTATTTTAGCCTATAGTAAGGTTTCTTTGAAAGCTGCAAGCTGGCTTAGGGACCCAAA
ACCTACAAAGCAAAGGCAAA

Product: hydrogenase large subunit

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNPVSEVTRLRRDIFTRVAHWALNHPLDVPMEMDISQVVKEIIPDGPARYRCCIHKERAIVEERIKIAVGLIQPEHRVTV
ISEACNGCSLNKYVVTDACQNCVAHPCRNSCPKKAISVIQNRAFIDQNSCVECGKCANACPYNAIIEVTRPCERACALKA
IKVDDSRKAVIDHELCASCGLCVTVCPFGAITDHSQMIDVICSLRVSEQPHVAVIAPAIAGQFGLKVSPDQIKAALLKLG
FDEVIEAALGADMVAQEEAGEIKLHAEDKKIMLNSCCPAVVKAVSLKLPELKDCISTTLSPMRVTGKLIKERYDNRVITV
FIGPCIAKKEEATHGDEIDMVLTFEELAAIFSASELEISSLEPVELKDASPNGRLFARAGGVSTAVRKHLGEMELNVLRV
QGLGQCLTTLKTSAKKSDSNFTFIECMACEGGCVGGPGTMVASTVGTRAVEKHAGESIILPK

Sequences:

>Translated_462_residues
MNPVSEVTRLRRDIFTRVAHWALNHPLDVPMEMDISQVVKEIIPDGPARYRCCIHKERAIVEERIKIAVGLIQPEHRVTV
ISEACNGCSLNKYVVTDACQNCVAHPCRNSCPKKAISVIQNRAFIDQNSCVECGKCANACPYNAIIEVTRPCERACALKA
IKVDDSRKAVIDHELCASCGLCVTVCPFGAITDHSQMIDVICSLRVSEQPHVAVIAPAIAGQFGLKVSPDQIKAALLKLG
FDEVIEAALGADMVAQEEAGEIKLHAEDKKIMLNSCCPAVVKAVSLKLPELKDCISTTLSPMRVTGKLIKERYDNRVITV
FIGPCIAKKEEATHGDEIDMVLTFEELAAIFSASELEISSLEPVELKDASPNGRLFARAGGVSTAVRKHLGEMELNVLRV
QGLGQCLTTLKTSAKKSDSNFTFIECMACEGGCVGGPGTMVASTVGTRAVEKHAGESIILPK
>Mature_462_residues
MNPVSEVTRLRRDIFTRVAHWALNHPLDVPMEMDISQVVKEIIPDGPARYRCCIHKERAIVEERIKIAVGLIQPEHRVTV
ISEACNGCSLNKYVVTDACQNCVAHPCRNSCPKKAISVIQNRAFIDQNSCVECGKCANACPYNAIIEVTRPCERACALKA
IKVDDSRKAVIDHELCASCGLCVTVCPFGAITDHSQMIDVICSLRVSEQPHVAVIAPAIAGQFGLKVSPDQIKAALLKLG
FDEVIEAALGADMVAQEEAGEIKLHAEDKKIMLNSCCPAVVKAVSLKLPELKDCISTTLSPMRVTGKLIKERYDNRVITV
FIGPCIAKKEEATHGDEIDMVLTFEELAAIFSASELEISSLEPVELKDASPNGRLFARAGGVSTAVRKHLGEMELNVLRV
QGLGQCLTTLKTSAKKSDSNFTFIECMACEGGCVGGPGTMVASTVGTRAVEKHAGESIILPK

Specific function: Unknown

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 49978; Mature: 49978

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVSEVTRLRRDIFTRVAHWALNHPLDVPMEMDISQVVKEIIPDGPARYRCCIHKERAI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
VEERIKIAVGLIQPEHRVTVISEACNGCSLNKYVVTDACQNCVAHPCRNSCPKKAISVIQ
HHHHHHHHHEEECCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHCCHHHCCCHHHHHHHHH
NRAFIDQNSCVECGKCANACPYNAIIEVTRPCERACALKAIKVDDSRKAVIDHELCASCG
HHHCCCCCCCCCHHCCCCCCCCHHHEEECCHHHHHHHEEEEEECCCCHHHHHHHHHHHCC
LCVTVCPFGAITDHSQMIDVICSLRVSEQPHVAVIAPAIAGQFGLKVSPDQIKAALLKLG
CEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHCC
FDEVIEAALGADMVAQEEAGEIKLHAEDKKIMLNSCCPAVVKAVSLKLPELKDCISTTLS
HHHHHHHHHCCHHHHHCCCCCEEEEECCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCC
PMRVTGKLIKERYDNRVITVFIGPCIAKKEEATHGDEIDMVLTFEELAAIFSASELEISS
HHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEECC
LEPVELKDASPNGRLFARAGGVSTAVRKHLGEMELNVLRVQGLGQCLTTLKTSAKKSDSN
CCCEEECCCCCCCCEEEECCCHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHCCCCCCC
FTFIECMACEGGCVGGPGTMVASTVGTRAVEKHAGESIILPK
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure
MNPVSEVTRLRRDIFTRVAHWALNHPLDVPMEMDISQVVKEIIPDGPARYRCCIHKERAI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
VEERIKIAVGLIQPEHRVTVISEACNGCSLNKYVVTDACQNCVAHPCRNSCPKKAISVIQ
HHHHHHHHHEEECCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHCCHHHCCCHHHHHHHHH
NRAFIDQNSCVECGKCANACPYNAIIEVTRPCERACALKAIKVDDSRKAVIDHELCASCG
HHHCCCCCCCCCHHCCCCCCCCHHHEEECCHHHHHHHEEEEEECCCCHHHHHHHHHHHCC
LCVTVCPFGAITDHSQMIDVICSLRVSEQPHVAVIAPAIAGQFGLKVSPDQIKAALLKLG
CEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHCC
FDEVIEAALGADMVAQEEAGEIKLHAEDKKIMLNSCCPAVVKAVSLKLPELKDCISTTLS
HHHHHHHHHCCHHHHHCCCCCEEEEECCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCC
PMRVTGKLIKERYDNRVITVFIGPCIAKKEEATHGDEIDMVLTFEELAAIFSASELEISS
HHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEECC
LEPVELKDASPNGRLFARAGGVSTAVRKHLGEMELNVLRVQGLGQCLTTLKTSAKKSDSN
CCCEEECCCCCCCCEEEECCCHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHCCCCCCC
FTFIECMACEGGCVGGPGTMVASTVGTRAVEKHAGESIILPK
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]