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The map label for this gene is nuoE [H]

Identifier: 134299510

GI number: 134299510

Start: 1809287

End: 1809763

Strand: Reverse

Name: nuoE [H]

Synonym: Dred_1653

Alternate gene names: 134299510

Gene position: 1809763-1809287 (Counterclockwise)

Preceding gene: 134299511

Following gene: 134299509

Centisome position: 50.16

GC content: 43.4

Gene sequence:

>477_bases
ATGGGTACTGAGTGCACATGCAACTGTAATCAGTCGAAGTTGGATGCGCTTTTTGCTCAATATAAGGGCAATCCCAATGG
CCTTATTGTGGTCATGGCGGCCATTCAAGAATCTCAAGGGTACCTTCCCAAAGATTTGTTAGTAAGAACTGCCGAGGAGT
TAGGTGTTCCTCTCAGTGACGTTTACGGTGTGGCTACTTTTTATGCTGCCTTTAGCCTTCGTCCTAGGGGAAGACATTCC
GTGAACCTTTGTCTGGGAACAGCTTGTTATGTAAAAGGAGCACCTGAAGTTCAAAGTATGTTAGAAAAAGAAATGGGCAT
TAAAGCAGGTAATACCACGGAAGATCGGCGCTTTAGTCTGGATTTAGTAAGATGTTTGGGTGCCTGTGGTATTGCACCGG
TATTGACAGTAAACGGTGAAGTTTATCCCCGTATGACTGCAGAAAAAGTAACTGAAGTGTTAAGCAAATATGAATAA

Upstream 100 bases:

>100_bases
TTACTACCTTTAGTTTCGCTAGTTCTAATTTCAGATTAAAAAACAAGAAGCAGAATACGTAATGTCAAAATATTTGCTTC
CGACGAAAGGAGGAAACCAT

Downstream 100 bases:

>100_bases
TACCTCCAGGGAGGTGAAGATAAATGAATTTTAAAGAATTAGAATTGCTAAGAGCAACTGCTAAGGAAGGTATTAAATTA
CGTTTGGGTGAAGAACCATC

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MGTECTCNCNQSKLDALFAQYKGNPNGLIVVMAAIQESQGYLPKDLLVRTAEELGVPLSDVYGVATFYAAFSLRPRGRHS
VNLCLGTACYVKGAPEVQSMLEKEMGIKAGNTTEDRRFSLDLVRCLGACGIAPVLTVNGEVYPRMTAEKVTEVLSKYE

Sequences:

>Translated_158_residues
MGTECTCNCNQSKLDALFAQYKGNPNGLIVVMAAIQESQGYLPKDLLVRTAEELGVPLSDVYGVATFYAAFSLRPRGRHS
VNLCLGTACYVKGAPEVQSMLEKEMGIKAGNTTEDRRFSLDLVRCLGACGIAPVLTVNGEVYPRMTAEKVTEVLSKYE
>Mature_157_residues
GTECTCNCNQSKLDALFAQYKGNPNGLIVVMAAIQESQGYLPKDLLVRTAEELGVPLSDVYGVATFYAAFSLRPRGRHSV
NLCLGTACYVKGAPEVQSMLEKEMGIKAGNTTEDRRFSLDLVRCLGACGIAPVLTVNGEVYPRMTAEKVTEVLSKYE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=152, Percent_Identity=32.8947368421053, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788621, Length=130, Percent_Identity=36.1538461538462, Blast_Score=102, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17561328, Length=148, Percent_Identity=36.4864864864865, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859877, Length=148, Percent_Identity=32.4324324324324, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21355353, Length=151, Percent_Identity=31.1258278145695, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17148; Mature: 17017

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTECTCNCNQSKLDALFAQYKGNPNGLIVVMAAIQESQGYLPKDLLVRTAEELGVPLSD
CCCCEECCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHCCCHHH
VYGVATFYAAFSLRPRGRHSVNLCLGTACYVKGAPEVQSMLEKEMGIKAGNTTEDRRFSL
HHHHHHHHHHHCCCCCCCCEEEEEEEEHHEECCCHHHHHHHHHHHCCCCCCCCCCHHHHH
DLVRCLGACGIAPVLTVNGEVYPRMTAEKVTEVLSKYE
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GTECTCNCNQSKLDALFAQYKGNPNGLIVVMAAIQESQGYLPKDLLVRTAEELGVPLSD
CCCEECCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHCCCHHH
VYGVATFYAAFSLRPRGRHSVNLCLGTACYVKGAPEVQSMLEKEMGIKAGNTTEDRRFSL
HHHHHHHHHHHCCCCCCCCEEEEEEEEHHEECCCHHHHHHHHHHHCCCCCCCCCCHHHHH
DLVRCLGACGIAPVLTVNGEVYPRMTAEKVTEVLSKYE
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA