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The map label for this gene is nuoG [C]

Identifier: 134299511

GI number: 134299511

Start: 1810542

End: 1812521

Strand: Reverse

Name: nuoG [C]

Synonym: Dred_1654

Alternate gene names: 134299511

Gene position: 1812521-1810542 (Counterclockwise)

Preceding gene: 134299512

Following gene: 134299510

Centisome position: 50.23

GC content: 43.03

Gene sequence:

>1980_bases
ATGAGTGGAAAAATTACCATTAATGGTCAAATTATAGATTTTACCGATGAAAAGAATATTCTGGCTGTTGCACGAAAAGT
AGGTATTGATATCCCTACCCTCTGCTATCATCCTGAACTAACCATTGCGGGTGCTTGTCGTTTGTGTGTGGTAGAAATTG
AGAGAATGGGCGTTCAGGCTTCCTGTTCTACCGCTCCCACAGATGGTATGGTGGTTTATACCAATTCAGAAAAAGTTAAC
AGAGTACGCAAAATGGTACTGGAACTCCTTTTGGCAAATCACGACCGTGAGTGTACAACCTGTGACTCCAGCGGGGCTTG
CAAACTTCAAAAGTATGCCAATGACTATGGTATTAAACGTTTGCGCTATCCAAATCGTACAACAATGGCTCCATTGGATA
CTTCAAGCCTGTCTATTGTTCGGGATCCCAACAAGTGTATCCTATGCGGTTTATGTGTACGGGTATGTAAAGAAAAACAA
GGCATTGGTGTATGGGATTTCAAAAACCGTGGTTCTCGTACTGATATTGTTGCCGCTATGGATCAGCCTTTGTCTGAATC
TGCTTGTATTAACTGCGGTCAGTGCATCGCGGTTTGTCCTACAGGAGCCCTTACATCCAACTCCTCTTCTATACAAGAAA
TTTGGGCGGCCATTCGTGATCCTAAAAAGACCGTTGTTTGCCAGATAGCCCCGGCTCCCAGAGCAGCCCTCGGAGAAGAA
TTTGGCCTGGGTTCCGTTGATGTAACTAAAAAAGTCGTAACAGCTCTGCGTAAAATAGGTTTTGACAAAGTCTTCGACAC
AGTATTCACAGCCGATATGACAACCATCGAAGAGTCCAATGAATTTTTAAGCAGGCTTGTAAAGGGAGAGAATCTTCCCC
TCTTTACCTCCTGTTGCCCCGGTTGGGTAAAATATGCGGAGGAATTCCATCCTGAACTGCTTAGCAATTTATCGAGTTGC
CGGTCACCACAACAAATGTTTGGTGCTGTATTAAAGAAAAAGTACGCCAAGGAACTGGGGATTGCCCCACAAGATATGTT
TGTGGTATCGGTGATGCCCTGTACCGCTAAAAAATATGAAGCAAAACGTCCGGAGTTTACCACCGAAGGCGCCTATGATG
TAGACGCAGTATTAACAACTGTTGAAGCTGCCCGGATGATTAAAGAAGCTGGCATTATTTTCAATACACTAGAAGAATCG
GAATTTGACCAACCGATGCAACAAGCTACCGGTTCTGGAGTATTGTTTGGTACCACTGGTGGGGTAATGGAATCTGTCAT
TCGTTACGTTGCCGGGAAACTTCTCAATGCAGAAGGCCGAGTTGACGTAGAATTCACCCGTGGTATGGAAGATACTAAAA
TTGCCAGCATAAATGTAGGTGACAATAAGCTAAATCTGGCTGTGGTAAATGGACTGTCTGCCACAGAAGCTTTAATTCAA
AAGATCCAGTCTGGTGAATTAGATGTTCAGGCAGTAGAAGTTATGGCTTGTCCCGGTGGCTGTGTAGGAGGCGGCGGCCA
GCCCTTCCAAAATGATAACGAACACCGCAAAGCCAGGGCCAGTGAAATTTATGGTATTGATGCAAAACTAGAGCTTCATA
AAGCACAGGATAATGAAGATCTAAATAAAATTTTTGAAAAATATTGGGGTGGTTGCTGCAACCATGATACCCACCATGAT
TTGCACACCCACTATAATCCCAAAAGACGTGTTGCCGGTAATGAAATTGTAATCAAAGATGGTAATGGTCCAGAAATAAC
CGTATGTATTGGCGAAGGTTGCATGAAAAAAGGTTCCATTAGTTTAATAGAAAAGCTAGTTAACTTACCAGTTAAAGTCA
AAGGTGTTTTCTGTCTAGAAAACTGTGGCAACGGTGTATCCGTTAAGGTTAATGATGAAATCCTACACGTCACTCCAGAA
AATGCTTTAGAATCCATTCAAAAAAAGTGCGGTTGTAGTTGTGGTTGCTGCTCTAAATAG

Upstream 100 bases:

>100_bases
AATGTAGATCTCTGCTTGAAGTGCGGTGCTTGTATGGAAAAATGTAAGTTTGGCTCTATAGAGATCAGGTAGCTGGTTAT
CTGAGAAAGGGTGTGACGTA

Downstream 100 bases:

>100_bases
AAATGTTATAAACAGGTGCTTGTTTGCACCTGTTTTTTAATTTAGTGCAAGTAATTCAGATAGTTAATTTGTCGTTTAAA
ATCTTATAAAACTACTTGAC

Product: hydrogenase

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MSGKITINGQIIDFTDEKNILAVARKVGIDIPTLCYHPELTIAGACRLCVVEIERMGVQASCSTAPTDGMVVYTNSEKVN
RVRKMVLELLLANHDRECTTCDSSGACKLQKYANDYGIKRLRYPNRTTMAPLDTSSLSIVRDPNKCILCGLCVRVCKEKQ
GIGVWDFKNRGSRTDIVAAMDQPLSESACINCGQCIAVCPTGALTSNSSSIQEIWAAIRDPKKTVVCQIAPAPRAALGEE
FGLGSVDVTKKVVTALRKIGFDKVFDTVFTADMTTIEESNEFLSRLVKGENLPLFTSCCPGWVKYAEEFHPELLSNLSSC
RSPQQMFGAVLKKKYAKELGIAPQDMFVVSVMPCTAKKYEAKRPEFTTEGAYDVDAVLTTVEAARMIKEAGIIFNTLEES
EFDQPMQQATGSGVLFGTTGGVMESVIRYVAGKLLNAEGRVDVEFTRGMEDTKIASINVGDNKLNLAVVNGLSATEALIQ
KIQSGELDVQAVEVMACPGGCVGGGGQPFQNDNEHRKARASEIYGIDAKLELHKAQDNEDLNKIFEKYWGGCCNHDTHHD
LHTHYNPKRRVAGNEIVIKDGNGPEITVCIGEGCMKKGSISLIEKLVNLPVKVKGVFCLENCGNGVSVKVNDEILHVTPE
NALESIQKKCGCSCGCCSK

Sequences:

>Translated_659_residues
MSGKITINGQIIDFTDEKNILAVARKVGIDIPTLCYHPELTIAGACRLCVVEIERMGVQASCSTAPTDGMVVYTNSEKVN
RVRKMVLELLLANHDRECTTCDSSGACKLQKYANDYGIKRLRYPNRTTMAPLDTSSLSIVRDPNKCILCGLCVRVCKEKQ
GIGVWDFKNRGSRTDIVAAMDQPLSESACINCGQCIAVCPTGALTSNSSSIQEIWAAIRDPKKTVVCQIAPAPRAALGEE
FGLGSVDVTKKVVTALRKIGFDKVFDTVFTADMTTIEESNEFLSRLVKGENLPLFTSCCPGWVKYAEEFHPELLSNLSSC
RSPQQMFGAVLKKKYAKELGIAPQDMFVVSVMPCTAKKYEAKRPEFTTEGAYDVDAVLTTVEAARMIKEAGIIFNTLEES
EFDQPMQQATGSGVLFGTTGGVMESVIRYVAGKLLNAEGRVDVEFTRGMEDTKIASINVGDNKLNLAVVNGLSATEALIQ
KIQSGELDVQAVEVMACPGGCVGGGGQPFQNDNEHRKARASEIYGIDAKLELHKAQDNEDLNKIFEKYWGGCCNHDTHHD
LHTHYNPKRRVAGNEIVIKDGNGPEITVCIGEGCMKKGSISLIEKLVNLPVKVKGVFCLENCGNGVSVKVNDEILHVTPE
NALESIQKKCGCSCGCCSK
>Mature_658_residues
SGKITINGQIIDFTDEKNILAVARKVGIDIPTLCYHPELTIAGACRLCVVEIERMGVQASCSTAPTDGMVVYTNSEKVNR
VRKMVLELLLANHDRECTTCDSSGACKLQKYANDYGIKRLRYPNRTTMAPLDTSSLSIVRDPNKCILCGLCVRVCKEKQG
IGVWDFKNRGSRTDIVAAMDQPLSESACINCGQCIAVCPTGALTSNSSSIQEIWAAIRDPKKTVVCQIAPAPRAALGEEF
GLGSVDVTKKVVTALRKIGFDKVFDTVFTADMTTIEESNEFLSRLVKGENLPLFTSCCPGWVKYAEEFHPELLSNLSSCR
SPQQMFGAVLKKKYAKELGIAPQDMFVVSVMPCTAKKYEAKRPEFTTEGAYDVDAVLTTVEAARMIKEAGIIFNTLEESE
FDQPMQQATGSGVLFGTTGGVMESVIRYVAGKLLNAEGRVDVEFTRGMEDTKIASINVGDNKLNLAVVNGLSATEALIQK
IQSGELDVQAVEVMACPGGCVGGGGQPFQNDNEHRKARASEIYGIDAKLELHKAQDNEDLNKIFEKYWGGCCNHDTHHDL
HTHYNPKRRVAGNEIVIKDGNGPEITVCIGEGCMKKGSISLIEKLVNLPVKVKGVFCLENCGNGVSVKVNDEILHVTPEN
ALESIQKKCGCSCGCCSK

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=397, Percent_Identity=30.4785894206549, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI134284357, Length=367, Percent_Identity=26.158038147139, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI6912524, Length=367, Percent_Identity=26.158038147139, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI84452151, Length=367, Percent_Identity=26.158038147139, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI14165461, Length=404, Percent_Identity=25.990099009901, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI33519475, Length=210, Percent_Identity=32.3809523809524, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI145693161, Length=251, Percent_Identity=27.0916334661355, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71995015, Length=400, Percent_Identity=29, Blast_Score=148, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI32566231, Length=202, Percent_Identity=34.1584158415842, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193209088, Length=197, Percent_Identity=35.0253807106599, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17565758, Length=197, Percent_Identity=35.0253807106599, Blast_Score=113, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324089, Length=385, Percent_Identity=24.1558441558442, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI116007464, Length=410, Percent_Identity=27.8048780487805, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI116007470, Length=410, Percent_Identity=27.8048780487805, Blast_Score=172, Evalue=7e-43,
Organism=Drosophila melanogaster, GI116007466, Length=410, Percent_Identity=27.8048780487805, Blast_Score=172, Evalue=7e-43,
Organism=Drosophila melanogaster, GI116007468, Length=410, Percent_Identity=27.8048780487805, Blast_Score=172, Evalue=8e-43,
Organism=Drosophila melanogaster, GI116007462, Length=287, Percent_Identity=29.2682926829268, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24640559, Length=199, Percent_Identity=33.1658291457286, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24640557, Length=199, Percent_Identity=33.1658291457286, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 71649; Mature: 71518

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKITINGQIIDFTDEKNILAVARKVGIDIPTLCYHPELTIAGACRLCVVEIERMGVQA
CCCEEEECCEEEEECCCCCHHHHHHHHCCCCCCEEECCCEEEHHHHHHHHHHHHHCCCEE
SCSTAPTDGMVVYTNSEKVNRVRKMVLELLLANHDRECTTCDSSGACKLQKYANDYGIKR
ECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHCCEE
LRYPNRTTMAPLDTSSLSIVRDPNKCILCGLCVRVCKEKQGIGVWDFKNRGSRTDIVAAM
EECCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEC
DQPLSESACINCGQCIAVCPTGALTSNSSSIQEIWAAIRDPKKTVVCQIAPAPRAALGEE
CCCCCCHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHCCHH
FGLGSVDVTKKVVTALRKIGFDKVFDTVFTADMTTIEESNEFLSRLVKGENLPLFTSCCP
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHCCC
GWVKYAEEFHPELLSNLSSCRSPQQMFGAVLKKKYAKELGIAPQDMFVVSVMPCTAKKYE
HHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHC
AKRPEFTTEGAYDVDAVLTTVEAARMIKEAGIIFNTLEESEFDQPMQQATGSGVLFGTTG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHHHCCCHHHHCCCCEEEEECCH
GVMESVIRYVAGKLLNAEGRVDVEFTRGMEDTKIASINVGDNKLNLAVVNGLSATEALIQ
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHH
KIQSGELDVQAVEVMACPGGCVGGGGQPFQNDNEHRKARASEIYGIDAKLELHKAQDNED
HHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCEEEEECCCCCHH
LNKIFEKYWGGCCNHDTHHDLHTHYNPKRRVAGNEIVIKDGNGPEITVCIGEGCMKKGSI
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCH
SLIEKLVNLPVKVKGVFCLENCGNGVSVKVNDEILHVTPENALESIQKKCGCSCGCCSK
HHHHHHHCCCEEEEEEEEEECCCCCCEEEECCCEEEECCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SGKITINGQIIDFTDEKNILAVARKVGIDIPTLCYHPELTIAGACRLCVVEIERMGVQA
CCEEEECCEEEEECCCCCHHHHHHHHCCCCCCEEECCCEEEHHHHHHHHHHHHHCCCEE
SCSTAPTDGMVVYTNSEKVNRVRKMVLELLLANHDRECTTCDSSGACKLQKYANDYGIKR
ECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHCCEE
LRYPNRTTMAPLDTSSLSIVRDPNKCILCGLCVRVCKEKQGIGVWDFKNRGSRTDIVAAM
EECCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEC
DQPLSESACINCGQCIAVCPTGALTSNSSSIQEIWAAIRDPKKTVVCQIAPAPRAALGEE
CCCCCCHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHCCHH
FGLGSVDVTKKVVTALRKIGFDKVFDTVFTADMTTIEESNEFLSRLVKGENLPLFTSCCP
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHCCC
GWVKYAEEFHPELLSNLSSCRSPQQMFGAVLKKKYAKELGIAPQDMFVVSVMPCTAKKYE
HHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHC
AKRPEFTTEGAYDVDAVLTTVEAARMIKEAGIIFNTLEESEFDQPMQQATGSGVLFGTTG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHHHCCCHHHHCCCCEEEEECCH
GVMESVIRYVAGKLLNAEGRVDVEFTRGMEDTKIASINVGDNKLNLAVVNGLSATEALIQ
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHH
KIQSGELDVQAVEVMACPGGCVGGGGQPFQNDNEHRKARASEIYGIDAKLELHKAQDNED
HHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCEEEEECCCCCHH
LNKIFEKYWGGCCNHDTHHDLHTHYNPKRRVAGNEIVIKDGNGPEITVCIGEGCMKKGSI
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCH
SLIEKLVNLPVKVKGVFCLENCGNGVSVKVNDEILHVTPENALESIQKKCGCSCGCCSK
HHHHHHHCCCEEEEEEEEEECCCCCCEEEECCCEEEECCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]